Factors determining acceptance of illness in patients with arterial hypertension and comorbidities

Bijak, Magdalena; Olszanecka, Agnieszka; Palczynska, E.; Czarnecka, Danuta; Rajzer, Marek; Stolarz‐Skrzypek, Katarzyna

doi:10.33963/kp.15860

Cited by 4 publications

(3 citation statements)

References 18 publications

(22 reference statements)

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“…The frequency of adverse drug-induced symptoms in our participants, i.e., 54% in the case of the female patients and 41% for the male patients, was related with the age of the study population, the average being 62.84 years, as well as the presence of various comorbidities such as CAD, HF, AF, hypercholesterolemia, diabetes, respiratory disorders, and diseases of the digestive system, i.e., factors which promote polypharmacy and, as a result, increase a patient's risk of any drug-related events [10].…”

Section: Discussionmentioning

confidence: 99%

The occurrence of drug-induced side effects in women and men with arterial hypertension and comorbidities

et al. 2022

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Background:Women have been underrepresented in large clinical trials in hypertension, and the incidence of adverse drug reactions by sex has been not sufficiently described. Aims:The aim of the study was to determine the prevalence of adverse drug reactions in women and men with arterial hypertension and comorbidities and to assess the specific predisposing factors for adverse drug reactions by sex. Methods:The study population comprised consecutive hospitalized patients diagnosed with arterial hypertension and patients treated in an outpatient clinic, whose recruitment started in January 2019 aiming to reach 1000 participants. A structured questionnaire was used to gather the patients' demographic and clinical data and current or past cases of adverse drug reactions. Results:The study included 560 women and 440 men, with mean (standard deviation) age of 62.84 (14.96) years. Women were older than men, had a longer hypertension history, and suffered less frequently from other cardiovascular diseases. Women reported more frequently adverse drug reactions. The risk of drug-induced side effects in women increased with age (P = 0.03) and with coexistence of any respiratory disease (P = 0.04). In the case of male sex, the risk of adverse drug reactions increased with the occurrence of hypercholesterolemia (P = 0.03), and coexistence of any analyzed metabolic diseases (P = 0.04).Conclusions: Adverse drug reactions were reported more frequently by women. Older age and the presence of any respiratory disease increased the risk of adverse drug reactions in women, while in men, the risk was increased mainly by the presence of hypercholesterolemia or other metabolic diseases.

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Section: Discussionmentioning

confidence: 99%

The occurrence of drug-induced side effects in women and men with arterial hypertension and comorbidities

et al. 2022

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“…On the other hand, 10.1% of 786 selected patients at a reference center for the treatment of arterial hypertension met the MDIS criteria, which is a similar level to that observed in our population of patients with chronic hypertension [10].In our study population, MDIS occurred more frequently in women, and this observation was consistent with earlier observations both among the general population and among patients with administered drugs, as well as in a selected population of patients with arterialhypertension [9-10] [12-13]A longer known duration of arterial hypertension was associated with a more frequent occurrence of MDIS, which is a new observation not documented in the available literature. This dependence may be due to the more advanced age of patients reporting any drug-induced side effects in our population, as well as originate from a reduced acceptance of arterial hypertension in patients with longer disease duration[14]. The comorbidities that increase the risk of MDIS among our patients include diseases of the respiratory and digestive systems, rheumatoid and endocrine diseases.…”

mentioning

confidence: 95%

“…A higher number of comorbidities increases the risk of reduced acceptance of the underlying disease, i.e. arterial hypertension[14], which may translate into more meticulous patient reporting of ADRs, and as a consequence lead to a situation where the definition of MDIS is met more frequently.…”

mentioning

confidence: 99%

Multiple drug intolerance in patients with arterial hypertension: prevalence and determining factors

Polaczyk¹,

Olszanecka²,

Wojciechowska³

et al. 2023

Polish Archives of Internal Medicine

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Drug-related adverse reactions are an important cause of drug discontinuation among patients. MDIS (Multiple Drug Intolerance Syndrome), i.e., intolerance to 3 or more drug classes, is an even more serious clinical problem. We explored the prevalence of this clinical entity in hypertensive patients and analyzed which groups of patients are particularly prone to MDIS.At every doctor's visit attention should also be paid to the patient's medical history, including to cases of adverse drug reactions.

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Levels of adherence to treatment, illness perception and acceptance of illness in patients with coronary artery disease - descriptive and correlational study

Dugunchi,

Mudgal,

Marznaki

et al. 2024

BMC Cardiovasc Disord

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Background Understanding the disease and its acceptance significantly influence adherence to prescribed medications, a critical aspect in managing coronary artery disease (CAD). This study is designed to explore the multifaceted factors influencing medication adherence specifically in CAD patients. Of particular interest is investigating the interconnectedness between medication adherence, the perception of illness, and the level of acceptance of the illness itself among these individuals. Methods This cross-sectional study involved 280 confirmed CAD patients who were selected through a convenience sampling method adhering to predefined inclusion criteria. The study was conducted between March and September 2023. Three primary parameters—medication adherence, illness perception, and acceptance of illness—were evaluated using standardized tools: The Morisky Medication Adherence Scale-8, Illness Perception Questionnaire-Brief, and Acceptance of Illness Scale. Statistical analyses using SPSS (version 25) were used to analyze the data. Results Patients had moderate illness perception (51.82 ± 7.58) and low acceptance to illness (16.98 ± 4.75), and 61.8 of them adhered to their medication regimen. A positive relationship between acceptance of illness and medication adherence (r = 0.435, p-value < 0.01) was found. Level of education, type of drug and marital status had significantly impact on medication adherence, and gender, level of education, intention to stop drug and marital status were associated with acceptance of illness (p < 0.05). Conclusion These results underscore the pivotal role of medication adherence in CAD management. Future interventions should target improving illness perception and acceptance of illness among CAD patients to enhance their overall adherence to prescribed medications and ultimately improve disease management.

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Factors determining acceptance of illness in patients with arterial hypertension and comorbidities

Cited by 4 publications

References 18 publications

The occurrence of drug-induced side effects in women and men with arterial hypertension and comorbidities

The occurrence of drug-induced side effects in women and men with arterial hypertension and comorbidities

Multiple drug intolerance in patients with arterial hypertension: prevalence and determining factors

Levels of adherence to treatment, illness perception and acceptance of illness in patients with coronary artery disease - descriptive and correlational study

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