Factors associated with the presence of postoperative headache in elective surgery patients: a prospective single center cohort study

Matsota, Paraskevi; Christodoulopoulou, Theodora; Batistaki, Chrysanthi; Arvaniti, Chrysa; Voumvourakis, Konstantinos; Kostopanagiotou, Georgia

doi:10.1007/s00540-016-2285-z

Cited by 14 publications

(28 citation statements)

References 25 publications

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“…Postoperative headache (POH) is a common complication after surgical procedures, associated with increased morbidity, prolonged hospital stay, reduced quality of life, and additional economic burden (4)(5)(6)(7)(8)(9)(10). The incidence of POH reported in the literature varies substantially after different types of surgery (4,6,9,(11)(12)(13)(14)(15)(16)(17). Currently, some studies have been carried out to identify possible predictors for the occurrence of POH in patients undergoing craniotomy, general, spinal, orthopedic, gynecologic, and ear-nose-throat procedures (6,13,16,(18)(19)(20)(21).…”

Section: Introductionmentioning

confidence: 99%

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Predictors and nomogram models for postoperative headache in patients undergoing heart valve surgery

Wang¹,

Huang²,

Wang³

et al. 2021

J Thorac Dis

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Background: Headache is a frequent complication after cardiac surgery. However, studies on the risk factors of postoperative headache (POH) are rare. The purpose of this study was to identify independent risk factors for POH in patients undergoing heart valve surgery (HVS) and to develop and validate risk prediction models. Methods: Consecutive patients undergoing open HVS from 2016 to 2019 were enrolled in this study. Patients were randomly assigned to training and validation sets at a 2:1 ratio. Univariate and multivariate analysis were applied to identify independent predictors for POH in the training set. A nomogram predicting POH was developed based on these factors, and was validated in the independent validation set. Results: POH developed in 1,061 of the 3,853 patients (27.5%). The overall mortality was 2.9%, and it was significantly higher in patients with POH (4.3% versus 2.4%, P<0.001). In the training set, six independent predictors were identified by multivariate analysis, including female, smoking history, hypertension, headache history, left ventricular ejection fraction, and cardiopulmonary bypass time. The model demonstrated good discrimination in both the training (c-index: 0.811) and validation sets (c-index: 0.814), and calibration was assessed by visual inspection. A second nomogram was also constructed including only preoperative predictors, with good discrimination (c-index: 0.792) and calibration. The decision and clinical impact curves of the models showed good clinical utility. Conclusions: We developed and validated two risk prediction models for POH in patients undergoing HVS. The models may have clinical utility in individualized risk assessment and preventive interventions.

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Section: Introductionmentioning

confidence: 99%

“…Several related risk factors have been reported, such as age, female gender, previous history of headache, and anaesthetic drugs (13,18,22). However, there are only few reports available about the development of POH after cardiac surgery, and basically it's just used as a secondary outcome (23).…”

Section: Introductionmentioning

confidence: 99%

Predictors and nomogram models for postoperative headache in patients undergoing heart valve surgery

Wang¹,

Huang²,

Wang³

et al. 2021

J Thorac Dis

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“…Migraine was individually associated with postsurgical 30-day readmission for both of these types of pain. It is well known that patients with migraine are vulnerable in the perioperative phase with the headache occurring within hours and up to five days after surgery (21–23). Our data confirm these findings and add the information that both headache and abdominal pain after surgery are a mechanism of readmission to the hospital.…”

Section: Discussionmentioning

confidence: 99%

The association between migraine and hospital readmission due to pain after surgery: A hospital registry study

et al. 2018

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Background Migraine has been identified as a risk factor of 30-day hospital readmission after surgery. We aimed to further characterize this association examining pain as a potentially migraine-associated, preventable reason for readmission. Hypothesis Compared to patients with no migraine, surgical patients with migraine are at increased risk of 30-day hospital readmission with an admitting diagnosis specifying pain. Methods This hospital registry study examined 150,710 patients aged 18 years and above, who underwent surgery with general anesthesia and mechanical ventilation between 2007 and 2015 at a tertiary care center and two affiliated community hospitals in Massachusetts, USA. Results Migraine was associated with an increased risk of 30-day pain-related readmission after surgery (adjusted odds ratio 1.42 [95% confidence interval 1.15-1.75]). The association was stronger for migraine with aura (compared to migraine without aura: Adjusted odds ratio 1.69 [95% confidence interval 1.06-2.70]; compared to no migraine: Adjusted odds ratio 2.20 [95% confidence interval 1.44-3.37]). The predicted adjusted risk of pain-related 30-day readmissions was 9.1 [95% confidence interval 5.3-13.0] in 1000 surgical patients with migraine with aura and 5.4 [95% confidence interval 4.2-6.6] in 1000 patients with migraine without aura, compared to 4.2 [95% confidence interval 3.8-4.5] in 1000 patients with no migraine. Furthermore, migraine was associated with an increased risk of postsurgical 30-day readmission due to a priori defined migraine-related pain (headache or abdominal pain) (adjusted odds ratio 1.55 [95% confidence interval 1.20-2.00]). Conclusion Patients with migraine undergoing surgery are at increased risk of 30-day hospital readmission due to pain.

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“…There were 10 studies investigating the effect of caffeine peri-operatively and the development of post-operative headache [24][25][26][27][28][29][30][31][32][33] . Seven investigated caffeine withdrawal [24][25][26][27][28][29][30][31][32][33] and three studies administered oral caffeine to prevent post-operative headache [31][32][33] . Of the seven prospective studies investigating the effect of caffeine withdrawal, ve studies found caffeine withdrawal increased the incidence of post-operative headache [24][25][26][27][28][29][30][31][32][33] .…”

Section: Caffeine Use In the Peri-operative Periodmentioning

confidence: 99%

“…Seven investigated caffeine withdrawal [24][25][26][27][28][29][30][31][32][33] and three studies administered oral caffeine to prevent post-operative headache [31][32][33] . Of the seven prospective studies investigating the effect of caffeine withdrawal, ve studies found caffeine withdrawal increased the incidence of post-operative headache [24][25][26][27][28][29][30][31][32][33] . Three studies investigated the administration of caffeine to relieve post-operative headache [31][32][33] .…”

Section: Caffeine Use In the Peri-operative Periodmentioning

confidence: 99%

Use of Therapeutic Caffeine in Acute Care Post-operative and Critical Care Settings: a Scoping Review

Bright¹,

Raman

Laupland

2020

Preprint

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BackgroundCaffeine is the most utilised psychoactive drug worldwide. However, caffeine withdrawal and the therapeutic use of caffeine in intensive care and in the peri-operative period have not been well summarised. Our objective was to conduct a scoping review of caffeine withdrawal and use in the intensive care unit (ICU) and post-operative patients. MethodsPubMed, Embase, CINAHL Complete, Scopus and Web of Science were systematically searched for studies investigating the effects of caffeine withdrawal or administration in ICU patients and in the peri-operative period. Areas of recent systematic review such as pain or post-dural puncture headache were not included in this review. Studies were limited to adults. ResultsOf 2268 articles screened, 26 were included and grouped into two themes of caffeine use in in the peri-operative period and in the ICU. Caffeine withdrawal in the post-operative period increases the incidence of headache, which can be effectively treated prophylactically with peri-operative caffeine. There were no studies investigating caffeine withdrawal or effect on sleep wake cycles, daytime somnolence, or delirium in the intensive care setting. Administration of caffeine results in faster emergence from sedation and anaesthesia, particularly in individuals who are at high risk of post-extubation complications. There has only been one study investigating caffeine administration to facilitate post-anaesthetic emergence in ICU. Caffeine administration appears to be safe in moderate doses in the peri-operative period and in the intensive care setting. ConclusionsAlthough caffeine is widely used, there is a paucity of studies investigating withdrawal or therapeutic effects in patients admitted to ICU and further novel studies are a priority.

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Factors associated with the presence of postoperative headache in elective surgery patients: a prospective single center cohort study

Cited by 14 publications

References 25 publications

Predictors and nomogram models for postoperative headache in patients undergoing heart valve surgery

Predictors and nomogram models for postoperative headache in patients undergoing heart valve surgery

The association between migraine and hospital readmission due to pain after surgery: A hospital registry study

Use of Therapeutic Caffeine in Acute Care Post-operative and Critical Care Settings: a Scoping Review

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