Factors Associated With the Outcomes of Older Patients Operated Due to Hip Fractures

CORRÊA, FERNANDO GONZALEZ; SERIKAWA, LUAN TOSHIO; Nicolau, Roberto Bezerra; Ferres, Luis Felipe Brandt; Filho, João Carlos Pedro; Reis, Fernando Baldy dos; Cocco, Luiz Fernando

doi:10.1590/1413-785220233102e259371

Cited by 3 publications

(2 citation statements)

References 20 publications

(41 reference statements)

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“…[4] Correa et al reported that longer length of stay (LOS) is associated with higher mortality, readmission, and increased medical costs in HF patients. [5] The prolonged LOS places a significant burden on clinical care and undermines the equitable distribution of medical resources. [6] Therefore, more attention should be paid to identifying LOS-related factors to strengthen HF management, promote patient recovery, and reduce LOS.…”

Section: Introductionmentioning

confidence: 99%

Relationship between admission blood urea nitrogen levels and postoperative length of stay in patients with hip fracture: A retrospective study

Fan,

Bei,

Wang

2024

Medicine

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To investigate the relationship between admission blood urea nitrogen (BUN) levels and postoperative length of stay (LOS) in hip fracture (HF) patients. This retrospective study retrieved related data from the MIMIC-IV database, of which the laboratory variables were taken preoperatively. The patients were divided into 4 groups according to the BUN quartile levels. After exploring the nonlinear relationship between BUN and LOS by generalized additive model, their connection was further analyzed using the generalized linear models, quantile regression models, and interaction analysis. Receiver operating characteristic curve analysis and decision curve analysis were performed to evaluate its value in predicting first intensive care unit admission and in-hospital mortality. Totally 1274 patients with HF were enrolled in the study. There was a nonlinear relationship between BUN and LOS (P < .05). Besides, BUN was an independent predictor for LOS after adjusting different covariates in 3 models (P < .05). Age served as a significant interactor in this relationship (P < .05). Moreover, receiver operating characteristic curve and decision curve analysis revealed the predictive value of BUN for intensive care unit admission and in-hospital mortality in HF. Admission BUN level as a cost-effective and easy-to-collect biomarker is significantly related to LOS in patients with HF. It helps clinicians to identify potential high-risk populations and take effective preventions before surgery to reduce postoperative LOS.

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Section: Introductionmentioning

confidence: 99%

Relationship between admission blood urea nitrogen levels and postoperative length of stay in patients with hip fracture: A retrospective study

Fan,

Bei,

Wang

2024

Medicine

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“…Although the presence of T2DM is associated with an increased risk of death after hip fracture 15 , little has been published quantifying the risk of mortality after fracture surgery by combining elderly with T2DM as two risk factors. This study aims to investigate the clinical characteristics and 1-year all-cause mortality in elderly hip fracture patients with T2DM.…”

Section: Introductionmentioning

confidence: 99%

Clinical characteristics and 1-year all-cause mortality in elderly hip fracture patients with type 2 diabetes mellitus: a propensity score matching study

Zhao

et al. 2023

Preprint

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Aim Diabetes can seriously affect the prognosis of elderly patients with hip fractures. The aim of this study was to investigate the clinical characteristics and 1-year all-cause mortality in elderly hip fracture patients with type 2 diabetes mellitus (T2DM). Methods This retrospective study involved patients aged ≥ 65 years old after hip fracture surgery from 2017 to 2019. Patients were divided into T2DM group and non-T2DM group based on whether T2DM was diagnosed at admission. Propensity score matching (PSM) was performed in a ratio of 1:1 in the two groups for further comparison. Clinical outcomes included the laboratory results, imaging results, perioperative complications and 1-year all-cause mortality. Results In this study, a total of 1296 elderly hip fracture patients were collected, including 331 cases in T2DM group and 965 cases in non-T2DM group. After PSM, a total of 312 pairs of cases were obtained, and all baseline data were comparable (P > 0.05). The levels of total cholesterol, triglycerides, low-density lipoprotein cholesterol, Brain natriuretic peptide and C-reactive protein in T2DM group were higher than those in non-T2DM group, and the levels of high-density lipoprotein cholesterol was lower in T2DM group (P < 0.05). The level of left atrial diameter, left ventricular end-diastolic diameter, ventricular septal thickness and carotid medial thickness were higher in the T2DM group (P < 0.05). The incidence of perioperative anemia (56.1% vs 47.1%), hypoproteinemia (53.8% vs 45.8%), electrolyte disturbances (43.6% vs 30.4%), perioperative heart failure (41.3% vs 27.9%), perioperative arrhythmias (30.1% vs 17.6%), and lung infections (21.8% vs 12.2%) was statistically significant in T2DM group (P < 0.05). During the 1-year follow-up period, patients with T2DM were 2 times more likely to die than those without T2DM (HR = 2.104, 95% CI 1.437, 3.080). Conclusion Elderly patients with T2DM are more likely to have multiple comorbidities, they are more likely to have dyslipidemia and cardiac structural changes, the incidence of perioperative complications after hip fracture is high. T2DM is an independent risk factor for 1-year mortality in elderly patients with hip fractures, which increases the risk of death twofold. To improve the postoperative outcomes of patients with T2DM who have undergone hip fracture surgery, effective treatment models such as multidisciplinary collaboration and individualized management should be established.

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Complicações do tratamento cirúrgico de fraturas proximais de fêmur em idosos e seus fatores de risco

Salgueiro,

Fernandes,

Santiago

et al. 2024

Cuad. Ed. Desar.

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A fratura proximal de fêmur é aquela que acomete cabeça, colo ou região trocantérica do fêmur. É a fratura mais comum de membros inferiores e acomete principalmente pacientes idosos, na maioria dos casos, em situações de queda da própria altura. Essa enfermidade, nesse grupo populacional, está associada a diversas complicações e seus fatores de risco devem ser bem estabelecidos para uma prevenção e manejo adequados.

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Factors Associated With the Outcomes of Older Patients Operated Due to Hip Fractures

Cited by 3 publications

References 20 publications

Relationship between admission blood urea nitrogen levels and postoperative length of stay in patients with hip fracture: A retrospective study

Relationship between admission blood urea nitrogen levels and postoperative length of stay in patients with hip fracture: A retrospective study

Clinical characteristics and 1-year all-cause mortality in elderly hip fracture patients with type 2 diabetes mellitus: a propensity score matching study

Complicações do tratamento cirúrgico de fraturas proximais de fêmur em idosos e seus fatores de risco

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