Factors Associated With Rotavirus Vaccine Coverage

Abstract

BACKGROUND: Rotavirus vaccines (RVVs) were included in the US immunization program in 2006 and are coadministered with the diphtheria-tetanus-acellular pertussis (DTaP) vaccine, yet their coverage lags behind DTaP. We assessed timing, initiation, and completion of the RVV series among children enrolled in active gastroenteritis surveillance at 7 US medical institutions during 2014-2016. METHODS: We compared coverage and timing of each vaccine series and analyzed characteristics associated with RVV initiation and completion. We report odds ratios (ORs) and 95% confidence intervals (CIs) from multivariable logistic regression models. RESULTS: We enrolled 10 603 children. In 2015, $1 dose coverage was 91% for RVV and 97% for DTaP. Seven percent of children received their first DTaP vaccine at age $15 weeks versus 4% for RVV (P # .001). Recent birth years (2013-2016) were associated with higher odds of RVV initiation (OR = 5.72; 95% CI 4.43-7.39), whereas preterm birth (OR = 0.32; 95% CI 0.24-0.41), older age at DTaP initiation

Rotavirus vaccination in the US: a systematic review of vaccination coverage and completion

“…The search of online databases for this review was performed in May 2018. Since then one additional article has been published on this topic by Aliabadi et al 12 Their analysis of RV coverage, timing of initiation, and completion of the vaccine series among children enrolled in seven US medical institutions that serve as active gastroenteritis surveillance sites were consistent with the findings of the studies included in this review in that coverage for RV vaccines was found to be lower than DTaP vaccine and factors that were associated with higher likelihood of RV vaccine completion were recent birth years (2013-2016) and higher maternal education. Preterm birth, African-American race, and public or no insurance were associated with lower odds of RV vaccine completion and regional differences were also observed.…”

“…11 Furthermore, compared to the coverage of other childhood vaccines in the US, such as Diphtheria-Tetanus-acellular Pertussis (DTaP), coverage for RV vaccine lags behind despite having similar dosing schedules. 12 For instance, between 2006 and 2016, annual DTaP vaccine coverage rates among children aged 19-35 months ranged from 93.7% to 96.2%, whereas RV vaccine coverage levels increased but remained lower than DTaP vaccine coverage (43.9% in 2009 to 74.1% in 2016). 7,13,14 The age restrictions and lack of a catchup recommendation contribute to lower RV vaccine coverage compared to DTaP coverage in the US.…”

“…7,13,14 The age restrictions and lack of a catchup recommendation contribute to lower RV vaccine coverage compared to DTaP coverage in the US. 12 To help improve vaccination coverage for RV vaccines, it is important to understand vaccination series completion and compliance rates, for the two currently licensed RV vaccines in the US (RV1 and RV5). To address barriers to higher RV vaccine coverage rates and develop effective interventions to improve suboptimal coverage rates, it is also necessary to review the factors that influence coverage, completion, and compliance rates.…”

<p>Rotavirus Vaccine Coverage and Associated Factors Among a Rural Population: Findings from a Primary Health-Care Project in Two Northwest Ethiopia Districts</p>

“…6,16,17 Factors influencing immunization status of children vary among different sociodemographic, political, ethnic and cultural groups. Few previous studies revealed that maternal age above 25 years, higher maternal education, frequent number of primary care visits and high continuity of care [18][19][20] were associated with higher odds of rotavirus vaccine completion. Likewise, children of mothers with adequate knowledge of rotavirus had increased completion of rotavirus vaccine series.…”

Geospatial Variation in Rotavirus Vaccination in Infants, United States, 2010–2017

“…Because 99.8% of our cohort did not have a copayment, we do not believe there was financial disincentive, but other financial obstacles could exist. Previous studies suggest rotavirus vaccination is lower among persons with public or no insurance ( 9 ). Therefore, vaccination rates might be <68% in geographic regions with a high number of uninsured or underinsured children.…”