Factors associated with quality of dreams during general anesthesia: a prospective observational study

Yoshida, Akari; Fujii, Keisuke; Yoshikawa, Takanori; Kawamata, Tomoyuki

doi:10.1007/s00540-021-02942-8

Cited by 7 publications

(5 citation statements)

References 16 publications

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“…14,16 Propofol induced dreaming was reported to be related to anesthetics, depth of anesthesia, age, gender, preoperative psychological state and other factors. [6][7][8][9][10] However, the baseline information of our study was comparable among the groups. Matus et al 8 found that the Bispectral Index value of dreamers at 2 min after endoscopy initiation was lower than that of non-dreamers.…”

Section: Discussionmentioning

confidence: 76%

Influences of Propofol, Ciprofol and Remimazolam on Dreaming During Anesthesia for Gastrointestinal Endoscopy: A Randomized Double-Blind Parallel-Design Trial

Zhou,

Fu,

Liu

et al. 2024

DDDT

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To compare the influences of propofol, ciprofol and remimazolam on dreaming during painless gastrointestinal endoscopy. Methods: This study was a single-center, prospective, parallel-design, double-blind, randomized clinical trial. Between May 2023 and October 2023, patients undergoing elective painless gastrointestinal endoscopy were recruited and randomly allocated into one of the three groups. Demographic data, intraoperative information, incidence of dreaming, insufficient anesthesia and intraoperative awareness, type of dream, patient satisfaction score, adverse events, and improvement of sleep quality were collected. Results: The difference in incidence of dreaming among the three groups was not significant (33.33% vs 48.33% vs 41.67%, p=0.061). The number of patients with intraoperative hypotension in the propofol group was larger than that of the remimazolam group (32 vs 12, p=0.001). However, the cases of intraoperative hypotension between propofol group and ciprofol group or ciprofol group and remimazolam group were comparable (32 vs 22, p=0.122; 22 vs 12, p=0.064). The percentage of insufficient anesthesia between propofol group and remimazolam group was significant (13.33% vs 1.67%, p=0.001), while no statistical difference was detected between propofol group and remimazolam group or ciprofol group and remimazolam group (13.33% vs 5.00%, p=0.025; 5.00% vs 1.67%, p=0.150). The ability of propofol to improve sleep quality at 1st post-examination day was significantly better than that of remimazolam (86.21% vs 72.88%, p=0.015), while it was not significant between propofol group and ciprofol group or ciprofol group and remimazolam group (86.21% vs 80.36%, p=0.236; 72.88% vs. 72.88%, p=0.181). Incidence of intraoperative awareness, intraoperative hypoxia, type of dream, satisfaction score, adverse events during recovery, and sleep improvement on the 7th postexamination day was not significant among the groups. Conclusion: Anesthesia with propofol, ciprofol and remimazolam, respectively, for gastrointestinal endoscopy did not induce statistical difference in the incidence of dreaming, despite that all of them are more likely to induce pleasant dreams.

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Section: Discussionmentioning

confidence: 76%

Influences of Propofol, Ciprofol and Remimazolam on Dreaming During Anesthesia for Gastrointestinal Endoscopy: A Randomized Double-Blind Parallel-Design Trial

Zhou,

Fu,

Liu

et al. 2024

DDDT

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“…Studies have demonstrated that the main factors in uencing dreams during anesthesia include the kind and dosage of anesthetics, depth of anesthesia, sex, and preoperative psychological pretreatment [2,3,[15][16][17][18] . Furthermore, Yoshida et al [19] found that a less than 11 depression score of the HADS was highly correlated with positive dreams.…”

Section: Discussionmentioning

confidence: 99%

Dreaming during gastrointestinal endoscopy under propofol, ciprofol or remimazolam anesthesia: study protocol for a randomized, controlled, single-center trial

Zhou,

Xia,

Deng

et al. 2023

Preprint

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Background Dreaming sometimes occurs during sedation. It has been reported that factors such as different anesthetics, depth of anesthesia, age, sex, and preoperative psychological state may affect dreams. Ciprofol and remimazolam are novel choices for painless endoscopy. Herein, we aimed to investigate dreaming during gastrointestinal endoscopy under propofol, ciprofol and remimazolam anesthesia respectively. Methods This is a prospective, randomized, controlled, single-center clinical trial.Three hundred and sixty subjects undergoing elective painless gastroscopy, colonoscopy or gastroenteroscopy will be enrolled. Eligible subjects will undergo propofol-, ciprofol- or remimazolam-induced anesthesia to finish the examination. Interviews about the modified Brice questionnaire will be conducted in the recovery room. Incidence of dreaming is set as the primary outcome. Secondary outcomes include type of dreams, improvement of sleep quality, evaluation of patients, incidence of insufficient anesthesia and intraoperative awareness. Safety outcomes are the incidences of hypotension and hypoxia during examination and adverse events during recovery. Discussion This study may observe different incidences of dreaming and diverse types of dreams, which might lead to different evaluationsto the anesthesia procedure. Based on the coming results, anesthesiologists can make a better medication plan for patients who are going to undergo painless diagnosis and treatment. Trial registration This trial was registered at the Chinese Clinical Trial Registry on May 18, 2023 (registration number ChiCTR2300071565).

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“…Studies have demonstrated that the main factors influencing dreams during anesthesia include the kind and dosage of anesthetics, depth of anesthesia, sex, and preoperative psychological pretreatment [4,5,[20][21][22][23]. Furthermore, Yoshida et al [24] found that a less than 11 depression score of the HADS was highly correlated with positive dreams.…”

Section: Discussionmentioning

confidence: 99%

Dreaming during gastrointestinal endoscopy under propofol, ciprofol, or remimazolam anesthesia: study protocol for a parallel-design double-blind, single-center trial

Xia,

Zhou,

Deng

et al. 2024

Trials

View full text Add to dashboard Cite

Background Dreaming sometimes occurs during sedation. It has been reported that factors such as different anesthetics, depth of anesthesia, age, sex, and preoperative psychological state may affect dreams. Ciprofol and remimazolam are novel choices for painless endoscopy. Herein, we aimed to investigate dreaming during gastrointestinal endoscopy under propofol, ciprofol, and remimazolam anesthesia respectively. Methods This is a prospective, parallel-design double-blind, single-center clinical trial. Three hundred and sixty subjects undergoing elective painless gastroscopy, colonoscopy, or gastroenteroscopy will be enrolled. Eligible subjects will undergo propofol-, ciprofol-, or remimazolam-induced anesthesia to finish the examination. Interviews about the modified Brice questionnaire will be conducted in the recovery room. Incidence of dreaming is set as the primary outcome. Secondary outcomes include type of dreams, improvement of sleep quality, evaluation of patients, incidence of insufficient anesthesia, and intraoperative awareness. Safety outcomes are the incidences of hypotension and hypoxia during examination and adverse events during recovery. Discussion This study may observe different incidences of dreaming and diverse types of dreams, which might lead to different evaluations to the anesthesia procedure. Based on the coming results, anesthesiologists can make a better medication plan for patients who are going to undergo painless diagnosis and treatment. Trial registration This trial was registered at the Chinese Clinical Trial Registry on May 18, 2023 (registration number ChiCTR2300071565).

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Factors associated with quality of dreams during general anesthesia: a prospective observational study

Cited by 7 publications

References 16 publications

Influences of Propofol, Ciprofol and Remimazolam on Dreaming During Anesthesia for Gastrointestinal Endoscopy: A Randomized Double-Blind Parallel-Design Trial

Influences of Propofol, Ciprofol and Remimazolam on Dreaming During Anesthesia for Gastrointestinal Endoscopy: A Randomized Double-Blind Parallel-Design Trial

Dreaming during gastrointestinal endoscopy under propofol, ciprofol or remimazolam anesthesia: study protocol for a randomized, controlled, single-center trial

Dreaming during gastrointestinal endoscopy under propofol, ciprofol, or remimazolam anesthesia: study protocol for a parallel-design double-blind, single-center trial

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