Factors associated with positive thrombus findings at ultrasonography in COVID-19 ward patients who underwent imaging for suspected deep vein thrombosis under prophylactic anticoagulation

Özhan, Abdulkerim; Baştopçu, Murat

doi:10.1016/j.jvsv.2022.02.012

Cited by 3 publications

(3 citation statements)

References 26 publications

(26 reference statements)

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“…In addition, recent research performed on hospitalized COVID-19 patients reported that an uptrend of D-dimer, rather than a baseline measurement, is more valuable in predicting VTE and mortality [11][12][13]15]. Of note, a recent study by Özhan and Baştopçu [16] concluded that D-dimer on admission predicts the risk of VTE in hospitalized COVID-19 patients at a higher than usual cut-off value.…”

Section: Discussionmentioning

confidence: 99%

Association Of D-Dimer/Fibrinogen Ratio With Pulmonary Embolism In COVID-19 Patients

Topcu¹,

Yiğit²,

Altunyurt³

et al. 2022

Turk J Vasc Surg

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Aim: This study aimed to investigate whether the D-dimer / fibrinogen ratio (DDFR) measured on admission could be used as a diagnostic marker of pulmonary embolism (PE) in coronavirus disease 2019 (COVID-19) patients. Material and Methods: This single-center, retrospective, case-control study was conducted with 204 COVID-19 patients (131 males, 73 females; mean age: 62±15.4 years; range, 28 to 97 years) between October 18, 2020, and December 18, 2020. Patients were followed during the hospital stay and for 30 days after discharge. The primary outcome was the occurrence of radiologically confirmed PE. The DDFR was calculated using the following formula: DDFR=D-dimer (ng/mL) / fibrinogen (mg/dL). Results: Six (2.9%) patients experienced PE during the follow-up. D-dimer had 63.6% sensitivity and 76.2% specificity on admission to predict thromboembolism at a cut-off of 1,375 ng/mL (area under the curve (AUC)=0.687, 95% confidence interval (CI): 0.530-0.845, p<0.05). The DDFR had 75% sensitivity and 90.5% specificity on admission to predict thromboembolism at a cut-off of 5.41 (AUC =0.846, 95% CI: 0.728-0.965, p<0.05). Conclusion: A measurement of DDFR on admission does not provide incremental value over D-dimer to recognize patients who are at risk of developing PE during and early after hospitalization for COVID-19.

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Section: Discussionmentioning

confidence: 99%

Association Of D-Dimer/Fibrinogen Ratio With Pulmonary Embolism In COVID-19 Patients

Topcu¹,

Yiğit²,

Altunyurt³

et al. 2022

Turk J Vasc Surg

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“…I read with interest the article by Özhan et al entitled “Factors associated with positive thrombus findings at ultrasonography in COVID-19 ward patients who underwent imaging for suspected deep vein thrombosis under prophylactic anticoagulation”. 1 …”

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confidence: 99%

A critical issue in COVID-19 patients: Deep venous thrombosis

Ketencі

2023

Journal of Vascular Surgery: Venous and Lymphatic Disorders

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“…Our study aimed to identify which COVID-19 patients with a preliminary diagnosis of DVT should be prioritized for a timely venous duplex ultrasonography (US). 2 As Dr Ketenci mentioned, patients with persistent symptoms and suspicion of DVT underwent repeat duplex US according to the current guidelines. 3 However, we do not have data on how many of the patients requiring repeat US had positive findings and whose DVT was evident on repeat US.…”

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confidence: 99%