Factors associated with poor sleep quality in patients with multiple sclerosis differ by disease duration

Vitková, Marianna; Gdovinová, Zuzana; Rosenberger, Jaroslav; Szilasiová, Jarmila; Nagyová, Iveta; Mikula, Pavol; Krokavcova, Martina; Groothoff, Johan W.; Dijk, Jitse P. van

doi:10.1016/j.dhjo.2014.05.004

Cited by 49 publications

(42 citation statements)

References 31 publications

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“…Concerning the factors associated with poor sleep quality in men, the strongest association was observed with pain. Pain is a common symptom in MS and is reported by more than half of patients with MS (Vitková et al., ; Foley, Vesterinen, & Laird, ; Fernández‐Muñoz, Morón‐Verdasco, & Cigarán‐Méndez, ). Our observation that pain may worsen sleep more in men than in women with MS seems to be inconsistent with previous research in the general population or with other chronic diseases (Silveyra et al., ; Van Onselen, Aouizerat, & Dunn, ).…”

Section: Discussionmentioning

confidence: 99%

“…The prevalence of sleep problems in the MS population ranges from 47 to 62%, with a higher prevalence in women (Vitková et al., ; Lobentanz, Asenbaum, & Vass, ). Boe Lunde et al., ( found that women also had much poorer sleep quality in a sample of 90 patients with MS (Boe Lunde, Aae, & Indrevag, ).…”

Section: Introductionmentioning

confidence: 99%

“…The prevalence of sleep problems in the MS population ranges from 47 to 62%, with a higher prevalence in women (Vitková et al, 2014;Lobentanz, Asenbaum, & Vass, 2004). Boe Lunde et al,…”

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confidence: 99%

“…Factors associated with poor sleep quality in MS patients are very similar to those reported in the general population. A higher level of depression and/or anxiety, increased fatigue, and more severe pain or bladder dysfunction have all been reported as important contributors of poor sleep (Vitková et al, 2014;Merlino et al, 2009;Boe Lunde et al, 2012). Studies in the general population (Mallampalli & Carter, 2002) or in patients with other chronic disorders (Woosley, Lichtstein, & Taylor, 2012) explained the role of gender in sleep quality mostly by different prevalence rates of factors contributing to poor sleep in women and men.…”

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confidence: 99%

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Poor sleep quality in patients with multiple sclerosis: gender differences

et al. 2016

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Objectives: Most of the psychological and physical factors associated with poor sleep quality in patients with multiple sclerosis (MS) have a different prevalence in women and men but whether Author ManuscriptThis article is protected by copyright. All rights reserved or not these factors contribute differently to sleep quality in women and men with MS is not clear. The aim of this study was to identify possible gender differences in factors related to poor sleep quality in MS patients. Material and Methods:We collected data from 153 patients with MS. Patients filled out the Pittsburgh Sleep Quality Index (PSQI), the Hospital Anxiety and Depression Scale, and one item of the Short Form-36 regarding pain. Results:The best model of predictors of poor sleep quality consisting of gender, depression, anxiety, pain and the interaction between gender and pain showed that the only variable interacting with gender, which was significantly associated with poor sleep quality was pain (OR for interaction of pain with male gender was 15.4, 95% CI: 2.4; 39.5). Separate models for men and women consisting of pain, depression, anxiety, after adjustment for age, disease duration and disability showed that pain was the only variable associated with poor sleep quality in men (OR= 12.7, 95%CI: 1.9; 29.6), whereas depression (OR= 4.1, 95%CI: 1.3; 13.2) and anxiety (OR= 6.8, 95%CI: 2.4; 19.1) were in women. Conclusions:Factors contributing to poor sleep quality in MS patients differ by gender.Depression and anxiety are associated with poor sleep quality in women; whereas pain is in men.This highlights the need to apply gender specific approaches to the treatment of sleep disorders.

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Section: Discussionmentioning

confidence: 99%

Section: Introductionmentioning

confidence: 99%

“…The prevalence of sleep problems in the MS population ranges from 47 to 62%, with a higher prevalence in women (Vitková et al, 2014;Lobentanz, Asenbaum, & Vass, 2004). Boe Lunde et al,…”

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confidence: 99%

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confidence: 99%

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Poor sleep quality in patients with multiple sclerosis: gender differences

et al. 2016

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“…There is not sufficient data to support such a hypothesis that having a lesion close to the ventricle versus elsewhere in the brain might be more associated with unfavorable effects (10). Patients with MS have many clinical presentations such as osteoporosis, sleep disorders and many other complications (11,12). Recent publications confirm that the incidence and prevalence of MS in Isfahan province of Iran has been increasing rapidly, especially in females (13).…”

Section: Introductionmentioning

confidence: 98%

Demographic Analysis of Patients With Multiple Sclerosis; Individual Variability Related to the Time Interval

Tolou-Ghamari

2015

Arch Neurosci

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Background: According to the published articles, there is an increase in the prevalence of MS all over the world. Regarding demographic characteristics for unknown reasons, females are more affected than males. Objectives: The aim of this study was demographic analysis and model of changes in patients for three years in a local teaching hospital in Isfahan/Iran. Results: Of the total population studied, 75% were female. 32% and 33% of patients related to the age groups of 20 -30 and 30 -40 years, respectively. However the number of patients related to time interval I3 were 472, but there was an increase in the number of patients studied from I1 to I2 (394 vs. 634). Approximately 13% of total population had MS attack more than 4 to 19 times. Conclusions:In agreement with previous reports, due to unknown reasons, the number of patients in general and the number of females in particular were increased annually. Within this population due to inter-and intra-individual variability, pharmacokinetic studies seem to be valuable.

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