Factors associated with perceived loss of libido in people who inject opioids: Results from a community-based survey in France

Madrid, Laélia Briand; Morel, Stéphane; Ndiaye, Khadim; Mezaache, Salim; Castro, Daniela Rojas; Mora, Marion; Olivet, Fabrice; Laporte, Virginie; Protopopescu, Camélia; Carrieri, Patrizia; Roux, Perrine

doi:10.1016/j.drugalcdep.2018.05.030

Cited by 11 publications

(2 citation statements)

References 43 publications

(68 reference statements)

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“…Interestingly, men who reported recent sexual activity showed lower risk drug use practices than their counterparts who did not report being sexually active. This may be because higher frequency of opioid use is associated with reduced libido, and can induce impotence among men [42]. It may therefore be that men engaging in regular sexual activity are those using less opioids, and are therefore able to exercise greater care with each instance of injection.…”

Section: Discussionmentioning

confidence: 99%

Understanding hepatitis B, hepatitis C and HIV among people who inject drugs in South Africa: findings from a three-city cross-sectional survey

Scheibe¹,

Young²,

Moses³

et al. 2019

Harm Reduct J

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Background People who inject drugs (PWID) are at high risk for hepatitis C (HCV), hepatitis B (HBV) and HIV without accessible harm reduction programmes. Coverage of needle and syringe and opioid substitution therapy (OST) services in South Africa is below global recommendations and no hepatitis services exist for PWID. We assessed HCV, HBV and HIV prevalence and risk factors among PWID accessing harm reduction services in Cape Town, Durban and Pretoria to inform policy and programming. Methods We conducted a cross-sectional survey among PWID in these cities between August 2016 and October 2017. Participants were opportunistically sampled while accessing services. Study team members administered a questionnaire that assessed sociodemographic characteristics, drug use and sexual risk practices. We tested for HCV (antibody, viral load and genotype), HBV surface antigen (HBsAg) and HIV. Bivariate and multivariate analyses assessed associations with HCV serostatus. Results Nine hundred and forty-three PWID were included in the per protocol analysis. The majority (87%, 819/943) were male, the overall median age was 29 and most lived on the street (66%, 626/943). At last injection, 77% (722/943) reported using a new needle and syringe and 17% (163/943) shared equipment. HIV prevalence was 21% (196/926), HBsAg positivity 5% (47/936), HCV seroprevalence 55% (513/937), HCV viraemic prevalence (proportion tested with detectable HCV) 43% (404/937) and HCV viraemic rate (proportion HCV antibody positive with detectable HCV) 79% (404/513). HCV genotype 1a (73%, 270/368) was the most prevalent. In multivariate analysis, HCV infection was positively associated with residing in Pretoria (adjusted odds ratio (aOR) 1.27, 95% CI 1.21–1.34), living on the street (aOR 1.90, 95% CI 1.38–2.60), frequent injecting (aOR 1.58, 95% CI 1.15–2.16) and HIV infection (aOR 1.69, 95% CI 1.15–2.47), and negatively associated with black race (aOR 0.52, 95% CI 0.36–0.74) and sexual activity in the previous month (aOR 0.61, 95% CI 0.42–0.88). Conclusions HCV and HIV are major health threats affecting PWID in these cities. Access to OST and needle and syringe services needs to be increased and integrated with HCV services. Social and structural factors affecting PWID who live on the street need to be addressed.

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Section: Discussionmentioning

confidence: 99%

Understanding hepatitis B, hepatitis C and HIV among people who inject drugs in South Africa: findings from a three-city cross-sectional survey

Scheibe¹,

Young²,

Moses³

et al. 2019

Harm Reduct J

View full text Add to dashboard Cite

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“…In contrast with stimulants, opioids tend to dampen interest and desire for sex 49 and their influence on STI risk seems indirect, as a consequence of addiction. The physically painful withdrawal symptoms that accompany OUD can motivate high-risk sexual behaviors, such as trading sex for money or drugs, with greater dependence driving more frequent sexual transactions as well as drug use 50 .…”

Section: Direct and Indirect Influences Of Substance Use On Sexual Be...mentioning

confidence: 99%

Collateral Damage: A Narrative Review on Epidemics of Substance Use Disorders and Their Relationships to Sexually Transmitted Infections in the United States

et al. 2020

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Sexual Function and Alcohol and Other Drug Use

Hallinan

2020

Textbook of Addiction Treatment

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Factors associated with perceived loss of libido in people who inject opioids: Results from a community-based survey in France

Abstract: Our findings showed that full-opioid agonists could have a negative impact on libido when injected regularly. Libido can improve quality of life and should be routinely discussed through counseling in prevention services with people who inject drugs.

Cited by 11 publications

References 43 publications

Understanding hepatitis B, hepatitis C and HIV among people who inject drugs in South Africa: findings from a three-city cross-sectional survey

Understanding hepatitis B, hepatitis C and HIV among people who inject drugs in South Africa: findings from a three-city cross-sectional survey

Collateral Damage: A Narrative Review on Epidemics of Substance Use Disorders and Their Relationships to Sexually Transmitted Infections in the United States

Sexual Function and Alcohol and Other Drug Use

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