Factors Associated With Nonsurvival in Foals Diagnosed With Perinatal Asphyxia Syndrome

Gold, Jenifer R.; Chaffin, Keith; Burgess, Brandy A.; Morley, Paul S.

doi:10.1016/j.jevs.2015.12.004

Cited by 6 publications

(9 citation statements)

References 16 publications

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“…Overall, survival was 77.6% for calves diagnosed with NE in this study. This is similar to a recent foal retrospective that reported 79.8% survival but higher than another that reported a 45.6% survival . The only risk factors associated with calf nonsurvival in this study were birth to a primiparous dam or being a twin; however, this is difficult to interpret given the low number of nonsurvivors.…”

Section: Discussionsupporting

confidence: 83%

“…The only risk factors associated with calf nonsurvival in this study were birth to a primiparous dam or being a twin; however, this is difficult to interpret given the low number of nonsurvivors. Factors related to foal nonsurvival in foals with NE include seizures, FTPI, prematurity, and placental abnormality . While FTPI was detected in calves in the current study, no prematurity, seizures, or placental abnormalities were noted in the medical records.…”

Section: Discussioncontrasting

confidence: 55%

“…This is similar to a recent foal retrospective that reported 79.8% survival 6 but higher than another that reported a 45.6% survival. 43 The only risk factors associated with calf nonsurvival in this study were birth to a primiparous dam or being a twin; however, this is difficult to interpret given the low number of nonsurvivors. Factors related to foal nonsurvival in foals with NE include seizures, FTPI, prematurity, and placental abnormality.…”

Section: Discussionmentioning

confidence: 77%

“…Given that the clinical signs associated with NE likely represent more than one underlying etiology in foals and infants, it might be that the calves in this study represent a certain subset of NE akin to the milder syndromes seen in foals. Another contributing factor could be that the median age of presentation for foals diagnosed with NE was 14 hours of age whereas 94.5% of the calves in this study were born in the hospital, allowing for earlier recognition of clinical signs.…”

Section: Discussionmentioning

confidence: 98%

“…Histopathologic evidence of hypoxic‐ischemic cerebral injury has not been demonstrated in a calf diagnosed with NE antemortem and may be absent on post‐mortem examination of foals diagnosed antemortem with NE . In an experimental model, in utero perinatal hypoxia in late gestation bovine fetuses resulted in stillbirth and abnormal mentation in the calves that survived.…”

Section: Discussionmentioning

confidence: 98%

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Neonatal Encephalopathy in Calves Presented to a University Hospital

Bianco

Moore

Taylor

2017

Veterinary Internal Medicne

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BackgroundWhile studies have examined bovine dystocia in relation to calf survival, little has been published regarding perinatal morbidity and treatment of newborn calves beyond failure of transfer of passive immunity (FTPI). Neonatal encephalopathy (NE) is a clinical syndrome commonly diagnosed in infants and foals but is poorly described in calves.Hypothesis/ObjectivesTo identify risk factors for development of NE in calves and factors predictive of survival.AnimalsNeonatal calves presented to a University hospital over a 10‐year period.MethodsRetrospective cohort study (2005–2015). Medical records of all neonatal calves presented to the hospital were examined, and cases of NE were identified. Data pertaining to demographics, dam parity, labor, treatment, and outcome were collected and analyzed with univariate and multivariate statistics.ResultsOf 200 calves in the final analysis, 58 (29%; 95% CI: 22.8–35.8%) were classified as NE and 142 calves as non‐NE. In univariate analysis, factors significantly associated with diagnosis of NE included male sex, presence of dystocia, abnormal position in the birth canal, and prolonged labor. In the multivariate model, only orientation of the calf in the birth canal remained significant (OR 2.14; 95% CI: 1.02–4.49; P = 0.044). Overall survival of calves with NE was good (45/58; 77.6%; 95% CI: 64.7–87.5); dam parity and being a twin was significantly associated with nonsurvival.ConclusionsCalves born after dystocia, especially if malpresented, should be closely monitored for nursing behavior within the first 24 hours of life. Prognosis for survival is good, but supportive care might be required for several days.

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Section: Discussionsupporting

confidence: 83%

Section: Discussioncontrasting

confidence: 55%

Section: Discussionmentioning

confidence: 77%

Section: Discussionmentioning

confidence: 98%

Section: Discussionmentioning

confidence: 98%

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