Factors associated with multidrug-resistant bacteria in secondary peritonitis: impact on antibiotic therapy

Séguin, Philippe; Laviolle, Bruno; Chanavaz, Charles; Donnio, Pierre Yves; Gautier-Lerestif, Anne-Lise; Campion, Jean‐Pierre; Mallédant, Yannick

doi:10.1111/j.1469-0691.2006.01507.x

Cited by 73 publications

(52 citation statements)

References 23 publications

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“…Both the long-term exposure to low doses and the failure to finish a prescription encourage more resistant bacterial strains to thrive (Homer et al, 2000). The universal problem of pathogen resistances to antibiotics is compounded by the emergence of opportunistic infections both fungal and bacterial infections (Seguin et al, 2006). The infectious diseases such as fungal dermatitis have become more frequent due to immuno compromised and immuno-suppressed conditions arising from HIV conditions.…”

Section: Results and Discussion Results For The Various Tests Of Thementioning

confidence: 99%

Antifungal and Antibacterial Activity of Crude Stem Bark Extracts of Bersama abysinicca Verdc. and Faurea saligna Harr.

Amuka¹,

Machocho²,

Okemo³

et al. 2015

Research J. of Medicinal Plant

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The two plant species were obtained from Mau Forest Complex in the Rift Valley, Kenya. Various parts of the two plants: Bersama abysinicca Verdc. Family, Melathiaceae and Faurea saligna Harr. Family, Proctaceae have been used in vogue by the Ogiek communities, who inhabit the area as their indigenous home, as source of traditional medicines for several ailments of human and livestock. Bersama abysinicca bark has been used in the management of blackwater east coast fever and rift valley fever in cattle. This study carried antimicrobial screening to uncover new antimicrobial agents from higher plants thus exposing their potentials. It is also aimed at demystifying the secrecy in which traditional African medicine has been shrouded for centuries. In the past, there has been no scientific verification to validate the efficacy of the traditional phytomedicine in the Ogiek community. Three methods were used to obtain various plant extracts. The first method was by obtaining crude plant extracts using methanol as a solvent. The second method was used by obtaining crude plant extracts through sequential extraction with ethyl acetate and petroleum ether as the third. Results showed that different plant species exhibited various bioactivities either on fungi, bacteria or on both categories of pathogens. The plant species extracts exhibited bactericidal and antifungal activities. Further researches should be carried out into the possibilities of formulation and commercialization of the plants as phytomedicine.

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Section: Results and Discussion Results For The Various Tests Of Thementioning

confidence: 99%

Antifungal and Antibacterial Activity of Crude Stem Bark Extracts of Bersama abysinicca Verdc. and Faurea saligna Harr.

Amuka¹,

Machocho²,

Okemo³

et al. 2015

Research J. of Medicinal Plant

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“…L'écologie microbienne est modifi ée dans les PPO, avec une fréquence accrue d'isolement d'espèces bactériennes de nature nosocomiale comme Pseudomonas aeruginosa, Enterobacter spp., Serratia spp., Citrobacter spp., Morganella spp., entérocoques multirésistants ou Candida spp. [26,[27][28][29][35][36][37] (tableau IV). Ces souches ont généralement une sensibilité réduite aux antibiotiques habituels à l'exception des carbapénèmes et du céfépime [28,29,37,38].…”

Section: Principes Généraux De L'antibiothérapie Des Ppounclassified

“…[26,[27][28][29][35][36][37] (tableau IV). Ces souches ont généralement une sensibilité réduite aux antibiotiques habituels à l'exception des carbapénèmes et du céfépime [28,29,37,38]. Il est à noter la présence possible de Staphylococcus aureus résistants à la méticilline et une réduction importante de sensibilité des souches d'Enterococcus faecium vis-à-vis des pénicillines avec une sensibilité à l'amoxicilline dans seulement 40 % des cas [28,29,38].…”

Section: Principes Généraux De L'antibiothérapie Des Ppounclassified

Infections intraabdominales postopératoires

Montravers

Mascitti

Balcan

2013

Références en Réanimation. Collection De La SRLF

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“…from cases of post-operative peritonitis [13], possibly due to prior antimicrobial use. Recovery of P. aeruginosa or Proteus spp.…”

Section: A N U S C R I P Tmentioning

confidence: 99%

Empirical first-line treatment with tigecycline for febrile episodes following abdominal surgery in cancer patients

Secondo¹,

Vassallo²,

Solari³

et al. 2010

International Journal of Antimicrobial Agents

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Cancer patients with complicated infections following abdominal surgery represent one of the worst clinical scenarios that is useful for testing the efficacy of empirical antimicrobial therapy. No study so far has evaluated the performance of tigecycline (TIG) when administered as empirical first-line treatment in a homogeneous population of surgical cancer patients with a febrile episode. An observational review of the data records of 24 sequential patients receiving TIG for a febrile episode following a major abdominal procedure in a single cancer institute was performed. Large bowel surgery represented 68% of all procedures, followed by gastric surgery (16%) and urinary-gynaecologic-biliary surgery (16%). Complications following surgery were observed in 68% of febrile episodes, with peritonitis and sepsis accounting for 59% and 24% of complications, respectively.Eight patients needed repeat surgery for source control. The mean duration of TIG treatment was 8 days. Causative pathogens were detected in 16 episodes (64%), and a total of 44 microorganisms were recovered (29% Escherichia coli, 9% Enterococcus faecalis and 9% coagulase-negative staphylococci). TIG was effective in 12 episodes (48%). The success rate was 67% when infectious episodes sustained by intrinsically resistant bacteria and fungi were excluded. Treatment failure was associated with the presence of complications and with microbiologically documented infection. TIG may be useful as a first-line treatment option in cancer patients requiring antibiotic treatment following surgery when complications are not present or suspected on clinical grounds and when local microbial epidemiology shows a low incidence of primary resistant bacteria.

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Factors associated with multidrug-resistant bacteria in secondary peritonitis: impact on antibiotic therapy

Cited by 73 publications

References 23 publications

Antifungal and Antibacterial Activity of Crude Stem Bark Extracts of Bersama abysinicca Verdc. and Faurea saligna Harr.

Antifungal and Antibacterial Activity of Crude Stem Bark Extracts of Bersama abysinicca Verdc. and Faurea saligna Harr.

Infections intraabdominales postopératoires

Empirical first-line treatment with tigecycline for febrile episodes following abdominal surgery in cancer patients

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