Factors associated with mortality in children under five years old hospitalized for Severe Acute Malnutrition in Limpopo province, South Africa, 2014-2018: A cross-sectional analytic study

Abstract

Background In South Africa, 30.9% of children under five years with Severe Acute Malnutrition (SAM) died in 2018. We aimed to identify factors associated with mortality among children under five years hospitalized with SAM in Limpopo province, South Africa. Methods We conducted a cross-sectional study including children under five years admitted with SAM from 2014 to 2018 in public hospitals of Limpopo province. We extracted socio-demographic and clinical data from hospital records. We used logistic regression to identify factors associated with mortality. Findings We included 956 children, 50.2% (480/956) male and 49.8% (476/956) female. The median age was 13 months (inter quartile range: 9-19 months). The overall SAM mortality over the study period was 25.9% (248/956). The most common complications were diarrhea, 63.8% (610/956), and lower respiratory tract infections (LRTIs), 42.4% (405/956). Factors associated with mortality included herbal medication use (adjusted Odds Ratio (aOR):

Status and utilization of child health and nutritional services among low-income urban households in Bangladesh

“…The analysis also indicated the causes of malnutrition among different under-five age groups: aged 0-23 months who were not breastfed within 1 h of birth; did not continue breastfeeding up to 6 months; and who were not fed an acceptable diet during 6-23 months of age. These findings are comparable to the other studies that investigated the malnourishment in under-five children in urban households (Ahsan et al 2017;Billah et al 2017;Gavhi et al 2020;Nalwanga et al 2020). Concerning nutritional services use, the number of children [aged 6-23 months] consumed Micro-Nutrient Powder and the children [aged 0-59 months] screened for nutrition status at facility and community levels were lower (0.02 to 0.05) in our both study areas, and the rates were lowest in Kashimpur.…”

Persistent Malnutrition and Associated Factors among Children under Five Years Attending Primary Health Care Facilities in Limpopo Province, South Africa

“…This was a cross-sectional study conducted in the Waterberg primary healthcare (PHC) facilities from July 2019 to December 2019. We used PHC facilities based on the evidence of malnutrition still observed among children under age five attending outpatient departments in facilities, as well as hospital admission and deaths resulting from severe acute malnutrition in Limpopo Province [ 23 , 25 ].…”

“…During 2017/2018, approximately 11,000 children under five years were treated for severe acute malnutrition, which was an underlying cause of mortality in 30.9% of these children [ 24 ]. Research is limited on malnutrition among children under age five in the health facilities in Limpopo Province [ 25 ], compared to several community-based studies [ 26 , 27 ] and national studies, which included the province [ 28 , 29 ]. In view of this, the aim of the study was to determine the prevalence of malnutrition in the form of stunting, underweight and thinness and associated factors among children aged under five years in the healthcare facilities of Waterberg district, Limpopo Province of South Africa.…”

Cardiac Derived CD51-Positive Mesenchymal Stem Cells Enhance the Cardiac Repair Through SCF-Mediated Angiogenesis in Mice With Myocardial Infarction

“…Although the molecular mechanism for the function of MSCs in facilitating engraftment and accelerating heart functional recovery is still unclear, the therapeutic efficacy of MSCs has increasingly been attributed in clinical trials ( Wang et al, 2012 ; Wollert et al, 2017 ). Importantly, the characteristics of MSCs are significantly different depending on their origin and therapeutic capability for cardiac vascular disease ( Gomes et al, 2013 ; Karantalis et al, 2015 ; Gavhi et al, 2020 ). However, numerous studies indicate that the success of the field will likely require our understanding of developmental biology and the role of the different types of MSCs, in order to refine their manufacturing and maximize their capacity to promote repair ( Amable et al, 2014 ; Heldman et al, 2014 ; Hare et al, 2017 ).…”