Factors associated with loss to follow-up in Tuberculosis treatment in the Huambo Province, Angola

Santos, Emilia Marcelina dos; Felgueiras, Óscar; Oliveira, Olena; Duarte, Raquel

doi:10.1016/j.pulmoe.2019.03.003

Cited by 6 publications

(8 citation statements)

References 3 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…It was observed that male patients were more regular in attending treatment follow-up appointments compared to the female patients. Gender differences in attending followup appointments have been reported for other disease conditions as well [42,43]. However, studies conducted in the United Kingdom and Canada have reported that female patients were more likely to attend treatment follow-up visits compared to their male counterparts [14,44].…”

Section: Discussionmentioning

confidence: 98%

“…Age was found to be significantly associated with regularity in treatment follow-up visits. Previously, mixed results have been reported in literature for the association between age and regular attendance at follow-up appointments [14,[42][43][44][45]. Increased disease severity or the presence of other co-morbidities among old age patients may encourage elderly patients to regularly attend treatment follow-up appointments.…”

Section: Discussionmentioning

confidence: 99%

See 1 more Smart Citation

Association between attendance at outpatient follow-up appointments and blood pressure control among patients with hypertension

Mahmood

Jalal

Hadi

et al. 2020

BMC Cardiovasc Disord

View full text Add to dashboard Cite

Objective The aim of this study was to assess the impact of regularity in treatment follow-up appointments on treatment outcomes among hypertensive patients attending different healthcare settings in Islamabad, Pakistan. Additionally, factors associated with regularity in treatment follow-up were also identified. Methods A cross-sectional study was undertaken in selected primary, secondary and tertiary healthcare settings between September, 2017 and December, 2018 in Islamabad, Pakistan. A structured data collection form was used to gather sociodemographic and clinical data of recruited patients. Binary logistic regression analyses were undertaken to determine association between regularity in treatment follow-up appointments and blood pressure control and to determine covariates significantly associated with regularity in treatment follow-up appointments. Results A total of 662 patients with hypertension participated in the study. More than half 346 (52%) of the patients were females. The mean age of participants was 54 ± 12 years. Only 274 (41%) patients regularly attended treatment follow-up appointments. Regression analysis found that regular treatment follow-up was an independent predictor of controlled blood pressure (OR 1.561 [95% CI 1.102–2.211; P = 0.024]). Gender (OR 1.720 [95% CI 1.259–2.350; P = 0.001]), age (OR 1.462 [CI 95%:1.059–2.020; P = 0.021]), higher education (OR 1.7 [95% CI 1.041–2.778; P = 0.034]), entitlement to free medical care (OR 3.166 [95% CI 2.284–4.388; P = 0.0001]), treatment duration (OR 1.788 [95% CI 1.288–2.483; P = 0.001]), number of medications (OR 1.585 [95% CI 1.259–1.996; P = 0.0001]), presence of co-morbidity (OR 3.214 [95% CI 2.248–4.593; P = 0.0001]) and medication adherence (OR 6.231 [95% CI 4.264–9.106; P = 0.0001]) were significantly associated with regularity in treatment follow-up appointments. Conclusion Attendance at follow-up visits was alarmingly low among patients with hypertension in Pakistan which may explain poor treatment outcomes in patients. Evidence-based targeted interventions should be developed and implemented, considering local needs, to improve attendance at treatment follow-up appointments.

show abstract

Section: Discussionmentioning

confidence: 98%

Section: Discussionmentioning

confidence: 99%

Association between attendance at outpatient follow-up appointments and blood pressure control among patients with hypertension

Mahmood

Jalal

Hadi

et al. 2020

BMC Cardiovasc Disord

View full text Add to dashboard Cite

show abstract

“…Lack of family support to TB patients was associated with over a two-fold increase in the risk of LTFU compared with those who had family support during treatment. Different studies have emphasized the importance of family support and also psychological support from healthcare workers to reduce or prevent LTFU from TB care and treatment [ 28 , 40 , 41 ]. In countries like Ethiopia , where the age-dependency ratio is high [ 42 ], supports including finance from active family members is essential for successful treatment completion.…”

Section: Discussionmentioning

confidence: 99%

Predictors of loss to follow-up among adult tuberculosis patients in Southern Ethiopia: a retrospective follow-up study

Watumo¹,

Mengesha

Gobena

et al. 2022

BMC Public Health

View full text Add to dashboard Cite

Background Loss to follow-up (LTFU) from tuberculosis (TB) treatment and care is a major public health problem as patients can be infectious and also may develop a multi-drug resistant TB (MDR-TB). The study aimed to assess whether LTFU differs by the distance TB patients travelled to receive care from the nearest health facility. Methods A total of 402 patient cards of TB patients who received care were reviewed from March 1–30, 2020. The Kaplan-Meir curve with the Log-rank test was used to compare differences in LTFU by the distance travelled to reach to the nearest health facility for TB care. The Cox proportional hazard regression model was used to identify predictors. All statistical tests are declared significant at a p-value< 0.05. Results A total of 37 patients were LTFU with the incidence rate of 11.26 per 1000 person-months of observations (PMOs) (95% CI: 8.15–15.53). The incidence rate ratio was 12.19 (95% CI: 5.01–35.73) among the groups compared (those who travelled 10 km or more versus those who travelled less than 10 km). Age ≥ 45 years (aHR = 7.71, 95% CI: 1.72, 34.50), educational status (primary schooling, aHR = 3.54, 95% CI: 1.49, 8.40; secondary schooling, aHR = 2.75, 95% CI: 1.08, 7.03), lack of family support (aHR = 2.80, 95% CI: 1.27, 6.19), nutritional support (aHR = 3.40, 95% CI:1.68, 6.89), ≥ 10 km distance to travel to a health facility (aHR = 6.06, 95% CI: 2.33, 15.81) had significantly predicted LTFU from TB treatment and care. Conclusions LTFU from adult TB care and treatment was 12 times higher among those who travelled ≥10 km to reach a health facility compared to those who travelled less. To retain adult TB patients in care and ensure appropriate treatment, health professionals and other stakeholders should give due attention to the factors that drive LTFU. We suggest identifying concerns of older patients at admission and those who travel long distance and establish social support platforms that could help people to complete TB treatment.

show abstract

“…Previous studies have identi ed several reasons and risk factors for treatment default among TB patients, including smoking, alcohol use, comorbidities (HIV and diabetes mellitus), accessibility to a healthcare centre, socioeconomic factors (age, sex, education level, and income), and poor family support (20)(21)(22). Treatment default is also common among those who previously defaulted on TB treatment and among relapse cases; defaulting is the most common during the intensive phase of treatment (23).…”

Section: Determinants Of Treatment Defaultsmentioning

confidence: 99%

Characteristics and Determinants of Treatment Default Among Smokers With Tuberculosis in an Industrial State of Malaysia: A Registry-based Study of the Years 2013-2017

Sharani

Ismail

Yasin

et al. 2021

Preprint

View full text Add to dashboard Cite

Background: The increased risk of treatment default among smokers raises concern over the secondary spread within the community. This study aimed to determine the prevalence and factors associated with treatment default among TB patients who smoke.Methods: A retrospective cohort of all registered TB patients who smoke in the state of Selangor between 2013 and 2017 via the Malaysian National MyTB database was included for analysis. TB patients who smoke were considered those with an active smoking status during the notification, while treatment default was defined as a TB patient who had interrupted treatment for 2 months or longer. There were 4 main variable domains included for analysis: sociodemographic profiles, disease profiles, treatment profiles, and comorbidities. Logistic regression analysis was used to identify determinants of treatment default among TB patients who smoke.Results: A total of 27.6% (N=6278) of the TB patients registered in Selangor were active smokers, and 15.1% (N=813) of the TB patients who smoke experienced defaulted TB treatment. The determinants of treatment default among TB patients who smoke were patients staying in an urban area (AOR 1.47; 95% CI 1.11,1.96), median income level less than RM2160 (AOR 2.0; 95% CI 1.34,2.99), no formal education (AOR 2.12; 95% CI 1.31,3.44), previously treated cases (AOR 2.78; 95% CI 1.99,3.88), active TB case detection methods (AOR 2.05; 95% CI 1.21,3.47), treatment duration of less than 6 months (AOR 7.56; 95% CI 5.74,9.92), and patients not on DOTS during the continuation phase (AOR 27.96; 95% CI 21.1,37.1). All the significant factors gave rise to the final model of determinants, with a predictability of 92.9% (95% CI 92.0,93.7).Conclusions: Our findings highlighted the high prevalence of treatment default among TB patients who smoke compared to the general TB population. Early risk detection that examines the two main domains of risk factors (socioeconomic factors and treatment profiles) should be provided for those who smoke in the TB population. Interventions should aim to reduce the prevalence of smoking among TB patients, together with close supervision during DOTS.

show abstract

Factors associated with loss to follow-up in Tuberculosis treatment in the Huambo Province, Angola

Cited by 6 publications

References 3 publications

Association between attendance at outpatient follow-up appointments and blood pressure control among patients with hypertension

Association between attendance at outpatient follow-up appointments and blood pressure control among patients with hypertension

Predictors of loss to follow-up among adult tuberculosis patients in Southern Ethiopia: a retrospective follow-up study

Characteristics and Determinants of Treatment Default Among Smokers With Tuberculosis in an Industrial State of Malaysia: A Registry-based Study of the Years 2013-2017

Contact Info

Product

Resources

About