Factors Associated with Intraocular Pressure before and during 9 Years of Treatment in the Collaborative Initial Glaucoma Treatment Study

Musch, David C.; Gillespie, Brenda W.; Niziol, Leslie M.; Cashwell, L. Frank; Lichter, Paul R.

doi:10.1016/j.ophtha.2007.08.010

Cited by 63 publications

(48 citation statements)

References 25 publications

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“…On the other hand, Law et al [6] report that a younger age is a risk factor for surgical failure of repeat trabeculectomy with MMC because older patients may have fewer activated fibroblasts and inflammatory cells than younger patients. Younger age was also found to be associated with higher IOP during 9 years of follow up in the Collaborative Initial Glaucoma Treatment Study [12]. In our study, however, age was not a significant risk factor in univariate analysis.…”

Section: Discussioncontrasting

confidence: 56%

Prognostic factors in trabeculectomy with mitomycin C having history of previous glaucoma surgery

et al. 2013

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Section: Discussioncontrasting

confidence: 56%

Prognostic factors in trabeculectomy with mitomycin C having history of previous glaucoma surgery

et al. 2013

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“…A new disposable probe was used for each patient. The measurement of the IOP with the GAT was performed by the following protocol [10,11]: a drop of 0.25% fluorescein with 0.5% proparacaine was administered topically in each eye, and the average of 2 sequential measurements were recorded; if the 2 measurements differed by >2 mm Hg, a 3rd measurement was made, and the median of the 3 measurements was recorded. Three consecutive measurements were made by the NCT, and the average was recorded.…”

Section: Methodsmentioning

confidence: 99%

Comparability of Icare Pro Rebound Tonometer with Goldmann Applanation and Noncontact Tonometer in a Wide Range of Intraocular Pressure and Central Corneal Thickness

et al. 2015

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Purpose: To evaluate the agreement between the reading values of the Goldmann applanation tonometer (GAT), Icare Pro rebound tonometer (IRT) and noncontact tonometer (NCT) in glaucoma patients. Methods: This cross-sectional study comprised 292 eyes of 292 patients selected from a glaucoma outpatient clinic. The intraocular pressure (IOP) was measured sequentially, at a 10-min interval each, in the following order: NCT, IRT and GAT. The central corneal thickness (CCT) was measured using Pentacam HR before the IOP measurements. Results: The mean IOPs measured by the GAT, NCT and IRT were 20.17 ± 6.73 mm Hg (range: 4-48), 19.77 ± 6.88 mm Hg (range: 3-46) and 19.30 ± 5.15 mm Hg (range: 7.30-44.5), respectively. The correlation coefficients of the GAT and IRT, NCT and IRT, and GAT and NCT measurements were r² = 0.673, r² = 0.663 and r² = 0.938 (all p < 0.001), respectively. The IRT tends to overestimate in the low GAT-measured IOPs, whereas it underestimates in high GAT-measured IOPs. The measurements of all 3 devices were also correlated with the CCT at a statistically significant level (GAT: r² = 0.063, NCT: r² = 0.063, IRT: r² = 0.058). Conclusion: The agreement between the IRT and GAT measurements is higher in the IOP range of 9-22 mm Hg, whereas significant discrepancies occur as the IOP deviates from normal values. The variability of the IRT and GAT measurements over a wide range of CCT is minimal.

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“…The fact, however, that glaucoma treatment is considered palliative rather than curative as well as the general absence of symptoms in glaucoma patients increases their risk of non-compliance. Analysis of the Collaborative Initial Glaucoma Treatment Study identified an important role of compliance for IOP control during treatment [5]. In the light of these findings, high rates of non-compliance with glaucoma treatment in different populations constitute a significant public health concern.…”

Section: Introductionmentioning

confidence: 99%

Compliance and knowledge about glaucoma in patients at tertiary glaucoma units

et al. 2011

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To document the rate of self-reported compliance and glaucoma-related knowledge in Swiss patients and to identify risk factors for their poor compliance. This was an observational study, including a total of 200 consecutive patients already under glaucoma medication in two Swiss tertiary glaucoma clinics (Geneva and Bern). Personal characteristics, presence of systemic disease, compliance with glaucoma medication, attitude to the ophthalmologist, and glaucoma-related attitudes were ascertained by means of a predetermined questionnaire with 40 questions. Patients were subsequently assessed for the ability to correctly instil placebo eye drops. Non-compliance with glaucoma medication was defined as omitting more than two doses a week as reported by the patient. Logistic regression was used to evaluate how patient characteristics and knowledge about the disease were related to compliance. Overall, 81% (n = 162) of patients reported to be compliant. Forgetfulness was the most frequently cited reason for non-compliance with dosing regimen (63%). Although 90.5% (n = 181) of patients believed glaucoma medication to be efficient, only 28% (n = 56) could correctly define glaucoma. Factors positively associated with compliance were 'knowledge of glaucoma' [adjusted odds ratio (OR) 4.77 (95% CI 1.36-16.70)] and 'getting help for administration of drops' ]. These findings indicate that despite the comparatively high compliance rate among glaucoma patients, knowledge of glaucoma remains poor in long-term glaucoma sufferers. Improving knowledge about the disease is important since it is positively associated with compliance in our study.

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Factors Associated with Intraocular Pressure before and during 9 Years of Treatment in the Collaborative Initial Glaucoma Treatment Study

Cited by 63 publications

References 25 publications

Prognostic factors in trabeculectomy with mitomycin C having history of previous glaucoma surgery

Prognostic factors in trabeculectomy with mitomycin C having history of previous glaucoma surgery

Comparability of Icare Pro Rebound Tonometer with Goldmann Applanation and Noncontact Tonometer in a Wide Range of Intraocular Pressure and Central Corneal Thickness

Compliance and knowledge about glaucoma in patients at tertiary glaucoma units

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