Factors Associated with In-hospital Mortality in Severe Burn Patients in Songklanagarind Hospital: A Retrospective Study

Mongkornwong, Atthawit; Sangthong, Rassamee; Tunthanathip, Thara; Sangkhathat, Surasak

doi:10.31584/jhsmr.2020775

Cited by 4 publications

(6 citation statements)

References 18 publications

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“…In addition to the importance of injury prevention and safety programs in mitigating burden, the role of medical services should also be considered. The total body surface area of burns greater than 55 of total bady surface area, with blood creatinine levels greater than 1.2 milligrams per deciliter, and facial burns were factors linked to higher mortality in a prior study 10 . If these factors could be avoided, the outcome might be improved 10 .…”

Section: Introductionmentioning

confidence: 82%

“…The total body surface area of burns greater than 55 of total bady surface area, with blood creatinine levels greater than 1.2 milligrams per deciliter, and facial burns were factors linked to higher mortality in a prior study 10 . If these factors could be avoided, the outcome might be improved 10 . The severity spectrum of such injuries may necessitate complex treatment by burn surgeons and intensive care services, which are not consistently accessible in all regions of the world.…”

Section: Introductionmentioning

confidence: 82%

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Epidemiology of Burn Injury in the Southern Border Provinces of Thailand

Suwansa-Ard

2023

J Health Sci Med Res

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Objective: This study aimed to investigate burns, from any situation, and the treatment in the Burn Center of Yala Hospital. Material and Methods: This research was a retrospective study in the Burn Center of Yala Hospital; from April 1, 2019 to May 31, 2021. Results: Enrollment consisted of 161 burn patients (male 65.8%, female 34.2%). Most burns in children were scalds (67.3%); whereas, in adults and the elderly they were flame burns (51.0% in adults and 66.7% in the elderly) (p-value<0.001), which were usually <20% of total body surface area (p-value<0.001). Most burns were superficial second degree burns. Patients in all age groups required surgical intervention (p-value=0.003). The median length of hospital stay was approximately seven days (IQR4-17); however, the elderly required intensive care more often than other age groups (p-value=0.003). All enrolled cases survived. Conclusion: The most common cause of burns in adults and the elderly was burning from flames, while burns from scalds occurred most in children. Burns in the elderly were more severe, and required admission to the intensive care unit more than any other age group.

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Section: Introductionmentioning

confidence: 82%

Section: Introductionmentioning

confidence: 82%

Epidemiology of Burn Injury in the Southern Border Provinces of Thailand

Suwansa-Ard

2023

J Health Sci Med Res

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“…Therefore, selecting GBM patients by predicted favorable prognosis has been proposed for the likelihood of TMZ cost-effectiveness in real-world situations. 24 Nomogram is one of the clinical prediction tools (CPT) that have been used for various diseases such as cancer, 25 trauma, 26,27 or degenerative disease. 28 Therefore, we proposed a web-based nomogram for prognostication that will be applied for selecting patients with a favorable prognosis when low-or middle-income settings need to allocate resources.…”

Section: Discussionmentioning

confidence: 99%

Prognostic Impact of the Combination of MGMT Methylation and TERT Promoter Mutation in Glioblastoma

Tunthanathip

Sangkhathat

Tanvejsilp

et al. 2021

JNRP

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Background The concept of combinational analysis between the methylation of O6-methylguanine-DNA methyltransferase (MGMT) and telomerase reverse transcriptase promoter (pTERT) mutation in glioblastoma (GBM) has been reported. The main study objective was to determine the prognosis of patients with GBM based on MGMT/pTERT classification, while the secondary objective was to estimate the temozolomide effect on the survival time of GBM with MGMT/pTERT classification. Methods A total of 50 GBM specimens were collected after tumor resection and were selected for investigating MGMT methylation and pTERT mutation. Clinical imaging and pathological characteristics were retrospectively analyzed. Patients with MGMT/pTERT classification were analyzed using survival analysis to develop the nomogram for forecasting and individual prognosis. Results All patients underwent resection (total resection: 28%, partial resection: 64%, biopsy: 8%). Thirty-two percent of all cases received adjuvant temozolomide with radiotherapy. Sixty-four percent of the case was found methylated MGMT, and 56% of the present cohort found pTERT mutation. Following combinational analysis of biomarkers, results showed that the GBMs with methylated MGMT and wild-type pTERT had a superior prognosis compared with other subtypes. Using Cox regression analysis with multivariable analysis, the extent of resection, postoperative chemoradiotherapy, MGMT/pTERT classification were associated with a favorable prognosis. Hence, a web-based nomogram was developed for deploying individual prognostication. Conclusions The interaction of MGMT methylation and pTERT mutation was confirmed for predicting prognosis. The results from the present study could help physicians create treatment strategies for GBM patients in real-world situations.

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“…Los factores de riesgo más frecuentes para el desarrollo de estas infecciones son: la edad, (niños <4 años y adultos > 60 años), el tamaño de SCTQ >20 a 30%, la lesión por inhalación (3)(4)(8)(9)(10), la internación prolongada y los múltiples procedimientos invasivos (6)(7)(8)(9)(10).…”

Section: Introductionunclassified

Prevenciòn de infecciones asociadas a cuidados de la salud en pacientes quemados

Biglia,

Clara,

Colque

et al. 2024

ASEI

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Las infecciones asociadas a cuidados de la salud(IACS) son una de las complicaciones más importantes que presentan los pacientes gran quemados. Aumentan su morbimortalidad, la duración de su estadía, el consumo de antimicrobianos, y los costos hospitalarios. Las tasas reportadas de IACS son muy variables entre los distintos países y centros de atención. El ánimo de ésta publicación es brindar el material necesario y actualizado de las medidas de control de infecciones que se deben implementar en la atención de los quemados ya que no es fácil disponer de información sobre este tema. En la presente revisión se analizaron estudios de distintas poblaciones, adultos y niños, con diferentes tipos quemaduras y diversos lugares de atención..Se utilizò como material de referencia las recomendaciones vigentes de la Sociedad Internacional de injurias por Quemaduras-ISBI- y se adicionaron publicaciones y experiencias de grupos de trabajo local e internacional referentes en el tema. Se describen cinco tipos de medidas de control y prevención de IACS:.Medidas generales, Medidas de higiene ambiental,Prevención de la infección de los lechos de las quemaduras,Profilaxis antibiótica y medidas de prevención de neumonía , infecciones asociadas a catèteres vasculares y vesicales en quemados. Conclusión: es esencial implementar un enfoque proactivo y multidisciplinario del control de infecciones en la atención de estos pacientes, generando recomendaciones adaptadas a la realidad de cada centro de salud, destinadas a disminuir las transmisiòn cruzada de microorganismos, utilizar los antimicrobianos tòpicos y sistémicos en forma adecuada, disminuir la multirresistencia, reducir las IACS y su mortalidad.

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Factors Associated with In-hospital Mortality in Severe Burn Patients in Songklanagarind Hospital: A Retrospective Study

Cited by 4 publications

References 18 publications

Epidemiology of Burn Injury in the Southern Border Provinces of Thailand

Epidemiology of Burn Injury in the Southern Border Provinces of Thailand

Prognostic Impact of the Combination of MGMT Methylation and TERT Promoter Mutation in Glioblastoma

Prevenciòn de infecciones asociadas a cuidados de la salud en pacientes quemados

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