Factors Associated With Hypertrophy of the Lingual Tonsils in Adults With Sleep-Disordered Breathing&lt;alt-title&gt;Factors Associated With Lingual Tonsil Hypertrophy&lt;/alt-title&gt;

Sung, Myung Whun; Lee, Woo Hyun; Wee, Jee Hye; Lee, Chul Hee; Kim, Eun‐Hee; Kim, Jeong Whun

doi:10.1001/jamaoto.2013.3263

Cited by 42 publications

(59 citation statements)

References 21 publications

Supporting

Mentioning

Contrasting

Unclassified

Order By: Relevance

“…The factors reducing the cross-sectional area lead to the development of OSA. The above is confirmed by the reports on apnoea in patients with neoplastic tumours of the upper airways [11], hypertrophied tonsils [29], and macroglossia [8,20]. The size of the upper airways cross-sectional area is also related to the craniofacial structure, which was demonstrated in earlier reports concerning narrowed cross-sections of the pharynx in patients with extreme micrognathia [27].…”

Section: Discussionsupporting

confidence: 69%

Craniofacial structure in patients with obstructive sleep apnoea

2016

View full text Add to dashboard Cite

show abstract

Section: Discussionsupporting

confidence: 69%

Craniofacial structure in patients with obstructive sleep apnoea

2016

View full text Add to dashboard Cite

show abstract

“…The lingual tonsil is an immunological organ composed of LT included in Waldeyer's ring . The use of TORS allows LTH resection with good postoperative results .…”

Section: Discussionmentioning

confidence: 99%

“…Lingual tonsil hypertrophy (LTH) is a clinical condition often observed in clinical practice during the inspection of the tongue base region . This lymphatic hypertrophy (LH) is implicated in a variety of airway pathologies, ranging from sleep‐related breathing disorders, lingual tonsillitis, and difficult intubation procedures . Additionally, it is frequently a cause of foreign body sensation in the throat and of pharyngodynia in cases of it inflammation …”

Section: Introductionmentioning

confidence: 99%

“…The etiology regarding the growth of this lymphatic tissue (LT) has not been clearly proved . The few studies about this topic showed that previous adenotonsillectomy, laryngopharyngeal reflux (LPR), and a high body mass index could be correlated to LTH, even if defined data regarding this aspect are not available …”

Section: Introductionmentioning

confidence: 99%

“…Robotic surgery allows blunt dissection of the excessive LT from the muscular plane of the BOT to achieve a complete resection of LT . However, the lingual tonsil LT does not present a capsule dividing it from the underlying tissues, as the palatine tonsils do; therefore, lymphatic cell aggregates may remain after the procedure, especially in the lateral region of the BOT …”

Section: Introductionmentioning

confidence: 99%

See 2 more Smart Citations

Lingual tonsil lymphatic tissue regrowth in patients undergoing transoral robotic surgery

Iannella

Magliulo²,

Montevecchi

et al. 2018

The Laryngoscope

View full text Add to dashboard Cite

Objectives/Hypothesis: To evaluate a possible regrowth of lingual tonsil lymphatic tissue in patients submitted to lingual tonsil resection with transoral robotic surgery (TORS).Study Design: Retrospective Study. Methods: Medical records of patients surgically treated by means of TORS to remove excessive lymphatic tissue of the lingual tonsil were retrospectively reviewed. Postoperative endoscopic data after long-term follow-up were analyzed to investigate possible lymphatic tissue regrowth. Preoperative and postoperative lingual tonsil lymphatic tissue were classified according to the standardized Friedman's grading scale ranging from 0 to 4.Results: Sixty-eight patients (41 male and 27 female; mean age = 51.3 years) were considered suitable for the study analysis. Clinical regrowth was observed in six (8.8%) patients: four (5.9%) and two (2.9%) patients with grade 2 and 3 lymphatic hypertrophy, respectively. No correlation between the grade of regrowth, the time interval from surgery, and the volume of lymphatic tissue removed was found.Conclusions: The lymphatic tissue regrowth after TORS resection appears to be very low.

show abstract

Obesity and Laryngopharyngeal Reflux as Risk Factors of Lingual Tonsil Hypertrophy in Patients With Sleep-Disordered Breathing: Validity of the Statistical Approach

Kawada

2014

JAMA Otolaryngol Head Neck Surg

View full text Add to dashboard Cite

To the Editor I read with interest the study by Sung et al 1 for97 patients with sleep-disordered breathing. They concluded that laryngopharyngeal reflux and body mass index were independent risk factors of lingual tonsil hypertrophy (LTH). I present some statistical concerns about their study. First, they described that multiple stepwise regression analyses were performed for the risk assessment. But they presented significant and insignificant factors simultaneously in their Table 3. I suppose that they used forced entry method instead of stepwise selection method.Second, nonnormal distribution of independent variables in multiple regression analysis is recommended to be converted to normal distribution to keep the residuals being normally distributed. Because the apnea-hypopnea index (AHI) presents nonnormal distribution in general, their conclusion that there is no association between respiratory parameters and LTH should be handled with caution. Please consider the transformation of the AHI as an independent variable of multiple regression analysis.Third, the adjusted R 2 value (the coefficient of determination) was 0.161. This means that under one-sixth of the total variance of LTH could be explained by their statistical model. Fourth, 97 patients were included in the multiple regression analysis, and this model requires at least 10 individuals per independent variable to show appropriate estimates.2 Sung et al selected 9 independent variables for their analysis, and more patients are required for keeping statistical validity (power) in their analysis. The authors quoted a reference describing the significant positive association between LTH and obesity, 3 but the target subjects were children. There was a decreasing tendency of LTH by aging in adults by multiple regression analysis. 1 Further study is needed with special reference to generation. The authors also quoted a reference describing the LTH by laryngopharyngeal reflux and/or obstructive sleep apnea-hypopnea syndrome, 4 but Friedman et al 4 mentioned that laryngopharyngeal reflux was not significantly associated with LTH by multiple regression analysis. This discrepancy should be verified by the follow-up study, which would give information on the causality of the association.

show abstract

Factors Associated With Hypertrophy of the Lingual Tonsils in Adults With Sleep-Disordered Breathing<alt-title>Factors Associated With Lingual Tonsil Hypertrophy</alt-title>

Abstract: Reflux finding score and body mass index were significantly associated with LTH in adults with sleep-disordered breathing, whereas the respiratory parameters were not associated with LTH.

Cited by 42 publications

References 21 publications

Craniofacial structure in patients with obstructive sleep apnoea

Craniofacial structure in patients with obstructive sleep apnoea

Lingual tonsil lymphatic tissue regrowth in patients undergoing transoral robotic surgery

Obesity and Laryngopharyngeal Reflux as Risk Factors of Lingual Tonsil Hypertrophy in Patients With Sleep-Disordered Breathing: Validity of the Statistical Approach

Contact Info

Product

Resources

About