Factors associated with functional impairment in symptomatic knee osteoarthritis

Creamer, Paul; Lethbridge-Çejku, Margaret; Hochberg, Marc C.

doi:10.1093/rheumatology/39.5.490

Cited by 376 publications

(333 citation statements)

References 36 publications

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“…This action minimizes the forces transmitted to the proximal joints in initial contact in gait. Accordingly, this muscle is important in knee stabilization and its weakness can generate abnormal stress mechanisms in the joint, leading to pain, 13 and resulting in postural instability and often falls. 2 In a study by O'Reilly et al 8 the authors also demonstrated inverse correlation of muscle strength of the quadriceps muscle in individuals with knee OA and reports of pain and functional disability.…”

Section: Discussionmentioning

confidence: 99%

“…Another relevant aspect is the association of the presence of pain with the occurrence of stiffness and alterations in functional activities, especially those related to knee flexion. 5,13,17 Leveille et al 17 demonstrated that in elderly individuals with OA the greatest difficulty in the performance of daily functions was related to muscle weakness developed in avoiding the execution of tasks that produced pain, such as climbing stairs or walking for a longer distance. Therefore, pain is an important and common clinical symptom in patients with OA, and can constitute a limiting factor of functional ability.…”

Section: Discussionmentioning

confidence: 99%

“…Since obesity is considered an important cause and exacerbating factor for OA, 12,13 weight and height were measured and the BMI (Kg/m 2 ) of the elderly women was calculated. The classification of the nutritional state was based on the WHO cut-off points for adults and elderly citizens: low weight (BMI<18.5kg/m 2 ), eutrophy (BMI 18.5-24.9kg/m 2 ), excess weight (BMI>25kg/m 2 ) and obesity (BMI>30kg/m 2 ).…”

Section: Instruments and Measurementsmentioning

confidence: 99%

“…The calculation of the average score was followed by that of the overall score, which aggregates a global dimension of OA. 13,14 Higher scores indicate a worse profile of pain, stiffness or functionality.…”

Section: Western Ontario and Mcmaster Universities Osteoarthritis Indmentioning

confidence: 99%

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Desempenho muscular, dor, rigidez e funcionalidade de idosas com osteoartrite de joelho

et al. 2011

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Objective: To determine the correlation between performance of the knee muscles and pain, stiffness, and functionality, through the Western Ontario and McMaster Universities Osteoarthritis Index (WOMAC) Questionnaire applied to an elderly population with osteoarthritis of the knee (OA). Methods: This study uses an observational, cross-sectional approach applied to a convenience sample of 80 elderly individuals (71.2 ± 5.3 years of age) with a clinical diagnosis of OA of the knee. Muscle strength, resistance, and balance of the knee were evaluated using the Biodex System 3 Pro isokinetic dynamometer at angular speeds of 60º/s and 180º/s. The self-reported functionality, presence of pain, and stiffness were evaluated by the WOMAC questionnaire. The correlation between the variables was analyzed by Spearman's coefficient of correlation (α = 0.05). Results: A significant inverse Acta Ortop Bras. 2011;19(4): 193-7All the authors declare that there is no potential conflict of interest referring to this article. correlation was observed between muscle strength and resistance of the quadriceps muscle (Q) and the hamstring muscle (H) at speeds of 60º/s and 180°/s, respectively, as well as in the relation between H/Q muscle balance at 180°/s and all domains of the WOMAC (p<0.05). Conclusions: The reduction in strength, resistance, and presence of imbalance in the knee muscles are inversely correlated with all the domains of the WOMAC in elderly individuals with OA. These results indicate a need for intervention that involves strengthening, resistance, and balance of the knee extensor and flexor muscles, aimed at reducing the impact of OA in relation to pain, stiffness, and functionality in elderly individuals. Level of Evidence: Level I, diagnostic studies -investigating a diagnostic test. ORiginAl ARticle

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Section: Discussionmentioning

confidence: 99%

Section: Discussionmentioning

confidence: 99%

Section: Instruments and Measurementsmentioning

confidence: 99%

Section: Western Ontario and Mcmaster Universities Osteoarthritis Indmentioning

confidence: 99%

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Desempenho muscular, dor, rigidez e funcionalidade de idosas com osteoartrite de joelho

et al. 2011

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“…Results have demonstrated that psychological factors (9 -13), demographic and clinical factors (9,11,14), biomechanical factors (10,15,16), and treatment modalities (10,17) are associated with disability. It is not known, however, whether these factors also predict future disabil-ity.…”

Section: Introductionmentioning

confidence: 99%

Course of functional status and pain in osteoarthritis of the hip or knee: A systematic review of the literature

Dijk

Dekker

Veenhof

et al. 2006

Arthritis & Rheumatism

216

149

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Objective. To systematically review studies describing the course of functioning in patients with osteoarthritis (OA) of the hip or knee and identifying potential prognostic factors. Methods. A systematic search was performed. Studies involving patients with hip or knee OA, >6 months of followup, and outcome measures on functional status or pain were included. Methodologic quality was assessed using a standardized set of 11 criteria; a qualitative data analysis was performed.Results. Approximately 6,500 titles and abstracts were screened and 48 publications were considered for inclusion. Eighteen studies, 4 of which met the high methodologic quality criteria, were included. For hip OA, there was limited evidence that functional status and pain do not change during the first 3 years of followup. After 3 years, however, a worsening of functional status and pain was seen. For knee OA, there was conflicting evidence for the first 3 years and limited evidence for worsening of pain and functional status after 3 years. Furthermore, limited evidence was established for negative associations between future functional status and laxity, proprioceptive inaccuracy, age, body mass index, and knee pain intensity. In contrast, greater muscle strength, better mental health, better self-efficacy, social support, and more aerobic exercise were protective factors in the first 3 years. Conclusion. Pain and functional status in hip or knee OA seem to deteriorate slowly, with limited evidence for worsening after 3 years of followup. In specific subgroups, prognosis in the first 3 years of followup was either worse or better, as both risk factors and protective factors were identified. Prognostic factors included biomechanical factors, psychological factors, clinical factors, and treatment modalities. To strengthen the evidence, further high-quality longitudinal research on hip or knee OA functioning is needed.

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Glucosamine Sulfate Use and Delay of Progression of Knee Osteoarthritis

Pavelka¹,

Gatterová²,

Olejárova³

et al. 2002

Arch Intern Med

608

157

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Factors associated with functional impairment in symptomatic knee osteoarthritis

Abstract: Function in symptomatic knee OA is determined more by pain and obesity than by structural change, at least as seen on plain X-ray. Our study provides further support for interventions targeting anxiety and helplessness in knee OA.

Cited by 376 publications

References 36 publications

Desempenho muscular, dor, rigidez e funcionalidade de idosas com osteoartrite de joelho

Desempenho muscular, dor, rigidez e funcionalidade de idosas com osteoartrite de joelho

Course of functional status and pain in osteoarthritis of the hip or knee: A systematic review of the literature

Glucosamine Sulfate Use and Delay of Progression of Knee Osteoarthritis

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