Factors Associated with Fecal Incontinence in Women of Childbearing Age with Crohnʼs Disease

Brochard, Charlène; Siproudhis, L.; Lévèque, Jean; Grouin, Amélie; Mallet, Anne-Laure; Bretagne, Jean–François; Ropert, Alain; Bouguen, Guillaume

doi:10.1097/mib.0000000000001056

Cited by 12 publications

(20 citation statements)

References 21 publications

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“…Faecal incontinence, usually defined as the uncontrolled loss or liquid of solid stool, is one of the concerns reported by IBD‐patients . Its prevalence amongst the IBD‐population, which has only been investigated in five studies to date, is estimated between 20% and 38% in tertiary centers and even up to 74% in a community‐based population . The latter has only been reported once, precluding reliable data on community‐based prevalence numbers of faecal incontinence and its association with quality of life.…”

Section: Introductionmentioning

confidence: 99%

Impacts of perianal disease and faecal incontinence on quality of life and employment in 1092 patients with inflammatory bowel disease

Vollebregt

Bodegraven

Kwaadsteniet³

et al. 2018

Aliment Pharmacol Ther

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SummaryBackgroundPatient reported outcomes regarding perianal disease and faecal incontinence in the community‐based inflammatory bowel disease population are poorly described.AimsTo determine the impacts of perianal disease and faecal incontinence on quality of life and employment in inflammatory bowel disease patients.MethodsFor this cross‐sectional study, a comprehensive survey was sent out to members of the Dutch National Crohn's and Colitis patient organisation. Validated questionnaires regarding faecal incontinence and active perianal disease were used to estimate its prevalence's. The effect on the quality of life (36‐Item Short Form Survey) and on employment status (multivariate binary regression analysis) was assessed in this inflammatory bowel disease population.ResultsA total number of 1092 returned questionnaires (58% responders) were used for analysis; 750 respondents (69%) were female; mean age was 47 years (IQR 35‐59). In 621 patients (57%) Crohn's disease, in 422 (39%) ulcerative colitis and in 49 (4%) patients unclassifiable inflammatory bowel disease was self‐reported. The 114 patients (10%) with a stoma were excluded for continence related analyses. Faecal incontinence was reported in 555 patients (57%), was comparable between the different inflammatory bowel disease diagnoses and affected all 36‐Item Short Form Survey subscales adversely (incontinence vs continence: Physical functioning 75 vs 84, P < 0.0001; Limitations due to physical health 49 vs 63, P < 0.0001; Limitations due to emotional problems 49 vs 64, P < 0.0001; Energy/fatigue 47 vs 53, P < 0.0001; Emotional well‐being 71 vs 74, P = 0.005; Social functioning 63 vs 73, P < 0.0001; Pain 66 vs 75, P < 0.0001; General health 41 vs 48, P < 0.0001). Active perianal disease was reported in 39% Crohn's disease, 16% ulcerative colitis (84% fissures) and 20% unclassifiable inflammatory bowel disease patients. Faecal incontinence was more common in patients with perianal disease (67% vs 53%, P = 0.003). When correcting for age, disease duration, inflammatory bowel disease‐related surgery and faecal incontinence, active perianal disease was independently affecting employment (OR 0.67; 95% CI 0.50–0.91; P = 0.01).ConclusionsFaecal incontinence and perianal disease are quality of life determining factors. Faecal incontinence needs more attention among clinicians, and development of new (drug) therapies needs to be focussed on perianal disease.

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Section: Introductionmentioning

confidence: 99%

Impacts of perianal disease and faecal incontinence on quality of life and employment in 1092 patients with inflammatory bowel disease

Vollebregt

Bodegraven

Kwaadsteniet³

et al. 2018

Aliment Pharmacol Ther

View full text Add to dashboard Cite

show abstract

“…Some focused only on female participants to determine the role of childbirth in IBDrelated FI 18,19 . Some reported both patients with UC and CD whilst others included either CD or UC patients alone.…”

Section: Resultsmentioning

confidence: 99%

“…Others found that this difference was nonsignificant 21 . Patients with a longer disease duration were at greater risk of FI 18 . This relationship was non-significant in another study 20 .…”

Section: Duration and Type Of Ibdmentioning

confidence: 95%

“…Active disease was significantly associated with the presence 2,16,18,21 and the severity of FI 16 . However, when using the inflammatory biomarker C-reactive protein (CRP), the relationship between disease activity and FI was not significant 16 .…”

Section: Disease Activitymentioning

confidence: 99%

“…There were mixed findings on age and FI. Some studies found that older patients reported more FI 18,22 , or more frequently 2 . However, this was not found in other studies.…”

Section: Agementioning

confidence: 99%

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