Factors Associated with Emergency Department Visits and Consequent Hospitalization and Death in Korea Using a Population-Based National Health Database

Park, Junhee; Yeo, Yohwan; Ji, Yonghoon; Kim, Tae Hyuk; Han, Kyungdo; Chul, Won; Son, Meong Hi; Jeon, Hong Jin; Park, Jaehyun; Shin, Dong Wook

doi:10.3390/healthcare10071324

Cited by 5 publications

(3 citation statements)

References 51 publications

(85 reference statements)

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“…This is expected considering the disease burden caused by smoking, which might result in more ED visits for smokers compared to nonsmokers. Current smoking as well as smoking relapse were found to be significantly associated with ED visits [ 20 - 24 ]. Access to the ED often reflects the first or the only contact of patients with the health care system; thus, the ED visit represents an opportunity to record smoking and nicotine use patterns.…”

Section: Introductionmentioning

confidence: 99%

Tobacco Smoking or Nicotine Phenotype and Severity of Clinical Presentation at the Emergency Department (SMOPHED): Protocol for a Noninterventional Observational Study

Campagna,

Farsalinos,

Costantino

et al. 2024

JMIR Res Protoc

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Background In the last few years, several nicotine products have become available as alternatives to smoking tobacco. While laboratory and limited clinical studies suggest that these devices are less toxic compared to classic tobacco cigarettes, very little is known about their epidemiological impact. Visiting the emergency department (ED) often represents the first or even the only contact of patients with the health care system. Therefore, a study conducted at the ED to assess the impact of these products on health can be reliable and reflect a real-life setting. Objective The aim of this noninterventional observational study (SMOPHED study) is to analyze the association between the severity of clinical presentation observed during ED visits among patients using various nicotine products and the subsequent outcomes, specifically hospitalization and mortality. Methods Outcomes (hospitalization and mortality in the ED) will be examined in relation to various patterns of nicotine products use. We plan to enroll approximately 2000 participants during triage at the ED. These individuals will be characterized based on their patterns of tobacco and nicotine consumption, identified through a specific questionnaire. This categorization will allow for a detailed analysis of how different usage patterns of nicotine products correlate with the clinical diagnosis made during the ED visits and the consequent outcomes. Results Enrollment into the study started in March 2024. We enrolled a total of 901 participants in 1 month (approximately 300 potential participants did not provide the informed consent to participate). The data will be analyzed by a statistician as soon as the database is completed. Full data will be published by December 2024. Conclusions There is substantial debate about the harm reduction potential of alternative nicotine products in terms of their smoking-cessation and risk-reduction potential. This study represents an opportunity to document epidemiological data on the link between the use of different types of nicotine products and disease diagnosis and severity during an ED visit, and thus evaluate the harm reduction potential claims for these products. International Registered Report Identifier (IRRID) PRR1-10.2196/54041

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Section: Introductionmentioning

confidence: 99%

Tobacco Smoking or Nicotine Phenotype and Severity of Clinical Presentation at the Emergency Department (SMOPHED): Protocol for a Noninterventional Observational Study

Campagna,

Farsalinos,

Costantino

et al. 2024

JMIR Res Protoc

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“…The number of emergency department (ED) visits has surged over the past several decades, with approximately 150 million annual visits recorded in the United States, and 10 million visits recorded in Korea [1][2][3]. This increase has given rise to challenges such as overcrowding in EDs and resource shortages [4].…”

Section: Introductionmentioning

confidence: 99%

Development of Prediction Model for Intensive Care Unit Admission Based on Heart Rate Variability: A Case–Control Matched Analysis

Choi,

Lee,

Joo

et al. 2024

Diagnostics

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This study aimed to develop a predictive model for intensive care unit (ICU) admission by using heart rate variability (HRV) data. This retrospective case–control study used two datasets (emergency department [ED] patients admitted to the ICU, and patients in the operating room without ICU admission) from a single academic tertiary hospital. HRV metrics were measured every 5 min using R-peak-to-R-peak (R-R) intervals. We developed a generalized linear mixed model to predict ICU admission and assessed the area under the receiver operating characteristic curve (AUC). Odds ratios (ORs) with 95% confidence intervals (CIs) were calculated from the coefficients. We analyzed 610 (ICU: 122; non-ICU: 488) patients, and the factors influencing the odds of ICU admission included a history of diabetes mellitus (OR [95% CI]: 3.33 [1.71–6.48]); a higher heart rate (OR [95% CI]: 3.40 [2.97–3.90] per 10-unit increase); a higher root mean square of successive R-R interval differences (RMSSD; OR [95% CI]: 1.36 [1.22–1.51] per 10-unit increase); and a lower standard deviation of R-R intervals (SDRR; OR [95% CI], 0.68 [0.60–0.78] per 10-unit increase). The final model achieved an AUC of 0.947 (95% CI: 0.906–0.987). The developed model effectively predicted ICU admission among a mixed population from the ED and operating room.

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“…This is expected considering the disease burden caused by smoking, which might result in more ED visits for smokers compared to non-smokers. Current smoking as well as smoking relapse were found to be signi cantly associated with ED visits [20][21][22][23][24]. Accessing at ED often re ects the rst or the only contact of patients with the healthcare system, thus, the ED visit represents an opportunity to record smoking and nicotine use patterns.…”

Section: Introductionmentioning

confidence: 99%

Relationship between tobacco and nicotine products use and clinical presentation at the Emergency Department: study protocol

Campagna

Farsalinos

Costantino

et al. 2023

Preprint

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Background In the last years several alternative to smoking nicotine products have become available. While laboratory and limited clinical studies suggest that these devices are less toxic compared to classic tobacco cigarettes, very little is still known about their epidemiological impact. Visiting the Emergency Department (ED) often represents the first or the only contact of patients with the healthcare system, so a study conducted at ED to assess the impact of these products on health is reliable and reflects the real life. Methods The study will be an observational study, with no intervention or randomization, to analyse the association between severity of clinical presentation during an ED visit as well as the outcome (hospitalization and death) and different patterns of nicotine products use. Approximately 1500–2000 people will be enrolled and categorized according to different pattern of tobacco and nicotine consumption through a specific questionnaire. Discussion There is a lot of debate about the harm reduction potential of alternative nicotine products in terms of their smoking-cessation and risk reduction potential. This study represents an opportunity to document epidemiological data on the link between different nicotine product use and disease diagnosis and severity during an ED visit, and thus evaluate the harm reduction potential claims for these products.

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Factors Associated with Emergency Department Visits and Consequent Hospitalization and Death in Korea Using a Population-Based National Health Database

Cited by 5 publications

References 51 publications

Tobacco Smoking or Nicotine Phenotype and Severity of Clinical Presentation at the Emergency Department (SMOPHED): Protocol for a Noninterventional Observational Study

Tobacco Smoking or Nicotine Phenotype and Severity of Clinical Presentation at the Emergency Department (SMOPHED): Protocol for a Noninterventional Observational Study

Development of Prediction Model for Intensive Care Unit Admission Based on Heart Rate Variability: A Case–Control Matched Analysis

Relationship between tobacco and nicotine products use and clinical presentation at the Emergency Department: study protocol

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