Factors associated with diphtheria vaccination completion among children under five years old in Peru 2010–2019: A cross-sectional population-based study

Gonzales, Antony; Choque, Deysi; Marcos-Carbajal, Pool; Salvatierra, Guillermo

doi:10.1016/j.heliyon.2022.e11370

Cited by 2 publications

(3 citation statements)

References 37 publications

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“…In the future, this vaccine administration interval can be used as a data entry for the characteristics of research subjects which also influences anti-pertussis antibody titer levels. [15][16][17][18][19][20] Another limitation of this study is that the measurement of anti-pertussis antibody levels was only carried out once with a cross-sectional design so that anti-pertussis antibody levels could not be seen clearly. The level of anti-pertussis antibodies after basic DPT vaccination is unknown so no preliminary data on the subject's anti-pertussis antibody levels was obtained as an indication of whether or not antipertussis antibodies were formed after vaccination.…”

Section: Discussionmentioning

confidence: 99%

Differences in Mean Anti-Pertussis Antibody Levels in Children with Acellular Pertussis Immunization and Whole Pertussis Without Booster

Rezki,

Rinang Mariko,

Rizanda Machmud

et al. 2024

Bioscmed

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Background: The incidence of pertussis is increasing every year, especially in developing countries. Low immunization coverage and decreased immunity are some of the factors causing the re-increase in pertussis cases. The protection provided by the pertussis vaccine whole and acellular pertussis given as a baby will decrease with age. This study aims to determine the difference in mean levels of anti-pertussis antibodies in children who received acellular pertussis and whole pertussis immunization without a booster. Methods: A cross-sectional study was carried out at the pediatric polyclinic of Dr. M. Djamil General Hospital Padang from December 2022 to December 2023. Research subjects were children aged 5-9 years with a history of whole pertussis immunization (DPwT) 3 times or acellular pertussis immunization (DPaT) 3 times. The research subjects were examined for anti-pertussis antibody titers using the ELISA technique. Results: Thirty-four children with a history of DPwT immunization 3 times and 34 children with a history of DPwT immunization 3 times were research subjects, with mean age 6.94±1.49 in the DPwT group and 6.88 ±1.61 in the DPaT group. The mean anti-pertussis antibody level in the DPwT group (9.54 IU/mL) was higher than the DPaT group (6.96 IU/mL) but was not statistically significant (p>0.05). The average antibody results showed that the antibody levels in both groups were below the antibody titer threshold that provides protection against pertussis. The results of the analysis showed that there was a significant difference in the incidence of AEFI between the DPwT and DPaT immunization groups (p<0.05). Conclusion: There was no difference in anti-pertussis antibody levels in children who received DPwT and DPaT immunization 3 times. Pertussis immunization is a required booster so that antibody levels are sufficient to provide protection against pertussis.

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Section: Discussionmentioning

confidence: 99%

Differences in Mean Anti-Pertussis Antibody Levels in Children with Acellular Pertussis Immunization and Whole Pertussis Without Booster

Rezki,

Rinang Mariko,

Rizanda Machmud

et al. 2024

Bioscmed

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“…So far, research related to diphtheria has focused more on analyzing the impact of diphtheria vaccine administration. Related to research on the factors involved, previous studies have stated that the risk factors that influence the occurrence of diphtheria cases are demographics [10,14], the administration of vaccines [1,14,15], and familial wealth [14]. For this reason, this research will forecast the number of diphtheria cases by involving the variables of various vaccines that have been obtained, the number of cases in the previous period, and population density.…”

Section: Related Workmentioning

confidence: 99%

“…There is still very little research that predicts the number of diphtheria cases involving population density variables and the number of cases in the previous period. So far, research related to diphtheria has focused more on analyzing the impact of vaccines on public health [4,8], distinguished by age group [5,15,16], population [14], demographics [10], area characteristics [17], changes in social behavior [18], and the size of the given country's income [19].…”

Section: Related Workmentioning

confidence: 99%

Forecasting the Case Number of Infectious Diseases Using Type-2 Fuzzy Logic for a Diphtheria Case Study

Anggraeni,

Firdausiah,

Perdana

2023

Itise 2023

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Factors associated with diphtheria vaccination completion among children under five years old in Peru 2010–2019: A cross-sectional population-based study

Cited by 2 publications

References 37 publications

Differences in Mean Anti-Pertussis Antibody Levels in Children with Acellular Pertussis Immunization and Whole Pertussis Without Booster

Differences in Mean Anti-Pertussis Antibody Levels in Children with Acellular Pertussis Immunization and Whole Pertussis Without Booster

Forecasting the Case Number of Infectious Diseases Using Type-2 Fuzzy Logic for a Diphtheria Case Study

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