Factors associated with dermatoporosis in a sample of geriatric patients in Mexico

Abstract

Introducción: La dermatoporosis es un síndrome crónico de fragilidad cutánea, caracterizado por atrofia, púrpura y pseudocicatrices en piel. Objetivo: Determinar los factores asociados a dermatoporosis en una muestra de sujetos ≥ 60 años. Métodos: Estudio observacional, transversal, descriptivo y analítico de sujetos ≥ 60 años a quienes se realizó historia clínica, exploración física y aplicación de un autocuestionario diagnóstico de dermatoporosis. Para determinar los factores asociados se realizó análisis de regresión logística multivariado. Resultados: En 315 sujetos, la prevalencia de dermatoporosis fue de 29 %; 70 % fue del sexo femenino. Los factores asociados fueron edad > 75 años (p = 0.001), exposición solar prolongada (p = 0.002), ingesta de anticoagulantes/antiplaquetarios (p = 0.004), esteroides orales (p = 0.03) y enfermedad renal crónica (p = 0.03); así como, edad materna > 40 años en el último parto (p = 0.02), lactancia > 7 meses por embarazo y lactancia acumulada > 18 meses (p = 0.01). Se relacionaron con su ausencia, edad < 20 años en el primer embarazo y menopausia después de los 45 años. La correlación entre la autovaloración y el diagnóstico clínico fue muy alta (0.95, p < 0.001). Conclusiones: Los factores de riesgo asociados a dermatoporosis fueron similares a los previamente reportados.

Prevalence and comorbidities of dermatoporosis: A French prospective observational study in general medicine consultation

“…We found a significant association between DP and the male gender, with a proportion of men more than twice that of women (sex ratio M/F: 2.5). As in other studies, [3][4][5][6][7][8] we confirm that age is a factor associated with DP. We found that occupational sun exposure was significantly associated with DP.…”

“…This condition appears to be more linked to prolonged sun exposure. 4,8 A combined effect was observed between the presence of CRF and the use of antiplatelet agents, suggesting the hypothesis that the frail elderly population with comorbidities and polymedication constitutes a 'prototype' of subjects at risk of DP.…”

“…2 Other factors also seem to be involved: genetic predisposition, prolonged sun exposure, use of corticosteroids.The few published epidemiological studies report a prevalence ranging from 4% to 37.5% in patients aged 50 years and over. [3][4][5][6][7][8] These epidemiological data are heterogeneous (i.e. recruitment age, hospitalized or ambulatory patients).No clinical study has evaluated the prevalence of DP and the comorbidities often cited in adults aged 60 years and over in general practice consultations.…”

“…The few published epidemiological studies report a prevalence ranging from 4% to 37.5% in patients aged 50 years and over. [3][4][5][6][7][8] These epidemiological data are heterogeneous (i.e. recruitment age, hospitalized or ambulatory patients).…”

“…Limitations of the study include focusing on upper limbs which are the most frequent site of DP stage 1 (92%-100%) [3][4][5][6][7][8] and the predominantly rural sample. Our study provides new insights into the prevalence, complications, and risk factors of DP in elderly.…”