Factors Associated with Caries Increment: A Longitudinal Study from 18 Months to 5 Years of Age

Meurman, Pia; Pienihäkkinen, Kaisu

doi:10.1159/000320717

Cited by 51 publications

(64 citation statements)

References 32 publications

Supporting

Mentioning

Contrasting

Unclassified

Order By: Relevance

“…Greater daily frequency of consumption of sweetened foods (AUC composite) was associated with greater incidence of early childhood caries (OR = 9.22, p = 0.002). Meurman and Pienihäkkinen [2010] found that the presence of MS, night feeding (yes vs. no), adding sugar to the diet (yes vs. no), and drinking of beverages other than water (yes vs. no) at age 18 months were significantly associated with caries incidence at age 42 months in 545 Finnish children. Laitala et al [2012] conducted survival analyses showing that MS-positive Finnish children (MS detected in their saliva at age 2 years, n = 29) had shorter time to having caries in both their primary and permanent teeth during the 10-year follow-up period compared to MS-negative children (no MS detected in their saliva at age 2 years, n = 119).…”

mentioning

confidence: 97%

Mutans Streptococci and Dental Caries: A New Statistical Modeling Approach

et al. 2018

View full text Add to dashboard Cite

Survival analyses have been used to overcome some of the limitations encountered with other statistical analyses. Although extended Cox hazard modeling with time-dependent variables has been utilized in several medical studies, it has never been utilized in assessing the complex relationship between mutans streptococci (MS) acquisition (time-dependent covariate) and time to having dental caries (outcome). This study involved secondary analyses of data from a prospective study conducted at the University of Alabama at Birmingham. Low socioeconomic status, African-American preschool children from Perry County, AL, USA (n = 95) had dental examinations at age 1 year and annually thereafter until age 6 years by three calibrated dentists. Salivary MS tests were done at ages 1, 1.5, 2, 2.5, 3, and 4 years. The patterns of and relationship between initial MS detection (time-dependent covariate) and dental caries experience occurrence were assessed, using extended Cox hazard modeling. The median time without MS acquisition (50% of the children not having positive MS test) was 2 years. Approximately 79% of the children had positive salivary MS tests by the age of 4 years. The median caries experience survival (50% of the children not having dental caries) was 4 years. During the follow-up period, 65 of the children (68.4%) had their initial primary caries experience. Results of the extended Cox hazard modeling showed a significant overall/global relationship between initial caries experience event at any given time during the follow-up period and having a positive salivary MS test at any time during the follow-up period (hazard ratio = 2.25, 95% CI 1.06-4.75). In conclusion, the extended Cox modeling was used for the first time and its results showed a significant global/overall relationship between MS acquisition and dental caries. Further research using causal mediation analysis with survival data is necessary, where the mediator “presence of MS” is treated as a time-dependent variable.

show abstract

mentioning

confidence: 97%

Mutans Streptococci and Dental Caries: A New Statistical Modeling Approach

et al. 2018

View full text Add to dashboard Cite

show abstract

“…To make informed decisions about prevention and restorative care, patients and their families, clinicians and researchers need to understand children's risk of developing caries and the factors that affect that risk. Because different individuals, teeth, and surfaces may have significantly variable risk of developing caries, it is important for the purpose of both clinical treatment and public health planning to identify those high-and low-risk 'units' -both children and teeth [Crall, 2007;Meurman and Pienihäkkinen, 2010]. Likewise, to judge which children and teeth are most likely to benefit from treatment, it is valuable to understand factors underlying heterogeneity of caries-preventive measures.…”

mentioning

confidence: 99%

Surface-Specific Efficacy of Fluoride Varnish in Caries Prevention in the Primary Dentition: Results of a Community Randomized Clinical Trial

Divaris¹,

Preisser²,

Slade

2012

Caries Res

View full text Add to dashboard Cite

Objectives: Fluoride varnish (FV) is efficacious in caries prevention although its effects among different tooth surfaces are poorly understood. This study sought to determine the extent to which caries-preventive effects of a community intervention that included FV application among preschool-aged children varied according to primary tooth anatomy and baseline tooth pathology. Methods: Secondary analysis was undertaken of data from a community-randomized controlled trial among 543 3- to 5-year-old Aboriginal children in 30 Northern Territory Australian communities. Children in intervention communities received community health promotion and FV application once every 6 months. Net caries (d₃mfs) risk and 95% confidence limits (CL) were estimated for the control and intervention arms, and stratified according to tooth anatomy/location and baseline pathology (sound, enamel opacity, hypoplastic defect or precavitated carious lesion). The intervention’s efficacy was quantified using generalized estimating equation modeling accounting for study design and clustering. The assumption of efficacy homogeneity was tested using a Wald χ² test with a p < 0.2 criterion and post hoc pairwise comparisons. Results: The intervention resulted in a 25% reduction (relative risk, RR = 0.75; 95% CL = 0.71, 0.80) in the 2-year surface-level caries risk. There was substantial heterogeneity in FV efficacy by baseline surface pathology: RRs were 0.73 for sound, 0.77 for opaque, 0.90 for precavitated, and 0.92 for hypoplastic surfaces. Among sound surfaces, maxillary anterior facials received significantly more benefit (RR = 0.62) compared to pits and fissures (RR = 0.78). Conclusion: The intervention had greatest efficacy on surfaces that were sound at baseline. Among those sound surfaces, maxillary anterior facials received most caries-preventive benefit.

show abstract

“…Studies have showed that the occurrence of the dental caries disease in patients with special needs (SNP) assumes significance [5], and that its prevalence can vary from 26.3% to 96.4% [6,7], according to the area and population studied, where this variability in the prevalence of the disease can happen due to the studies methodological variation. Beyond that, the high prevalence can be associated to specific factors as the socio-economic condition, limitation caused by the disability, difficulty of the caretakers in the performance and maintenance of the oral hygiene, frequent and regular consume of food high in sucrose, and use of continuous medication [8,9]. Individuals with neuropsychomotor disorders use medications as anticonvulsants and antispasmodics, antipsychotics, antidepressants and antiepileptics, during long periods [10].…”

Section: Introductionmentioning

confidence: 99%

Experience of Dental Caries and Use of Continuous Medication in Children with Neuropsychomotor Disorders

Hartwig¹,

Ferreira²,

Costa³

et al. 2016

Pesqui. bras. odontopediatria clín. integr.

View full text Add to dashboard Cite

Objective: To identify the relation between the use of continuous medication by children with neuropsychomotor disorders and the development of the dental caries disease. Material and Methods: The data were obtained from medical and dental records of children, who were assisted in an extension project of the Dentistry School of the Federal University of Pelotas. Socio-economic variables, the disability diagnosis, the type and frequency of the continuous medication, and the dental caries experience registered in the dental record were collected. The data were evaluated by double typing, analyzed by descriptive statistics, and the associations were tested by the Quisquared, Fisher exact, Mann-Whitney, and Kruskal-Wallis tests. The Stata Statistical Software, version 12.0, was utilized considering the level of significance of 5%. Results: 119 records were evaluated, and the results were distributed by age bracket due to the high age range. Undoubtedly, the cerebral palsy was the most prevalent (33.9%). From the total of the children, 68.8% were using continuous medication, and the majority (56%) uses medication there are more than 24 months. The anticonvulsants were the most used medications (33.8%), and 96.5% of the children used medication during the nocturnal period. Half of the utilized medications presented sucrose in its composition. Conclusion: A statistically significant association between the use of continuous medication, containing sucrose, and the dental caries experience were not observed, what suggests that other risk factors contribute to the disease installation.

show abstract

Factors Associated with Caries Increment: A Longitudinal Study from 18 Months to 5 Years of Age

Cited by 51 publications

References 32 publications

Mutans Streptococci and Dental Caries: A New Statistical Modeling Approach

Mutans Streptococci and Dental Caries: A New Statistical Modeling Approach

Surface-Specific Efficacy of Fluoride Varnish in Caries Prevention in the Primary Dentition: Results of a Community Randomized Clinical Trial

Experience of Dental Caries and Use of Continuous Medication in Children with Neuropsychomotor Disorders

Contact Info

Product

Resources

About