Factors associated with cardiovascular disease in the Brazilian adult population: National Health Survey, 2019

Gomes, Crizian Saar; Gonçalves, Renata Patrícia Fonseca; Silva, Alanna Gomes da; Sá, Ana Carolina Micheletti Gomide Nogueira de; Alves, Francielle Thalita Almeida; Ribeiro, Antônio Luiz Pinho; Malta, Déborah Carvalho

doi:10.1590/1980-549720210013.supl.2

Cited by 12 publications

(31 citation statements)

References 21 publications

(29 reference statements)

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“…The independent variables included were: sociodemographics [sex, age group ( 34 ), self-declared race/skin color ( 35 ), education ( 36 ), living with a spouse/partner, geographic region ( 37 ), and area of residence ( 37 )]; lifestyle [tobacco use ( 38 ), alcohol abuse ( 39 ), leisure-time physical activity ( 40 ), recommended consumption of fruits and vegetables ( 41 ), ultra-processed food consumption ( 41 ), regular consumption of soft drinks or artificial juices ( 41 ), and nutritional status ( 42 )]. Questions, answer options, operational definitions and, analysis categories are in Supplementary Table S2 .…”

Section: Methodsmentioning

confidence: 99%

Prevalence and factors associated with multimorbidity in adults in Brazil, according to sex: a population-based cross-sectional survey

Pereira

Pedroso

Batista

et al. 2023

Front. Public Health

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IntroductionMultimorbidity, defined as the coexistence of two or more chronic diseases in the same individual, represents a significant health challenge. However, there is limited evidence on its prevalence and associated factors in developing countries, such as Brazil, especially stratified by sex. Thus, this study aims to estimate the prevalence and analyze the factors associated with multimorbidity in Brazilian adults according to sex.MethodsCross-sectional population-based household survey carried out with Brazilian adults aged 18 years or older. The sampling strategy consisted of a three-stage conglomerate plan. The three stages were performed through simple random sampling. Data were collected through individual interviews. Multimorbidity was classified based on a list of 14 self-reported chronic diseases/conditions. Poisson regression analysis was performed to estimate the magnitude of the association between sociodemographic and lifestyle factors with the prevalence of multimorbidity stratified by sex.ResultsA total of 88,531 individuals were included. In absolute terms, the prevalence of multimorbidity was 29.4%. The frequency in men and women was 22.7 and 35.4%, respectively. Overall, multimorbidity was more prevalent among women, the older people, residents of the South and Southeast regions, urban area residents, former smokers, current smokers, physically inactive, overweight, and obese adults. Individuals with complete high school/incomplete higher education had a lower prevalence of multimorbidity than those with higher educational level. The associations between education and multimorbidity differed between sexes. In men, multimorbidity was inversely associated with the strata of complete middle school/incomplete high school and complete high school/incomplete higher education, while in women, the association between these variables was not observed. Physical inactivity was positively associated with a higher prevalence of multimorbidity only in men. An inverse association was verified between the recommended fruit and vegetable consumption and multimorbidity for the total sample and both sexes.ConclusionOne in four adults had multimorbidity. Prevalence increased with increasing age, among women, and was associated with some lifestyles. Multimorbidity was significantly associated with educational level and physical inactivity only in men. The results suggest the need to adopt integrated strategies to reduce the magnitude of multimorbidity, specific by gender, including actions for health promotion, disease prevention, health surveillance and comprehensive health care in Brazil.

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Section: Methodsmentioning

confidence: 99%

Prevalence and factors associated with multimorbidity in adults in Brazil, according to sex: a population-based cross-sectional survey

Pereira

Pedroso

Batista

et al. 2023

Front. Public Health

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“…Education: no education/incomplete middle school, complete middle school/incomplete high school, complete high school/incomplete higher education or complete higher education or more [ 21 ].…”

Section: Methodsmentioning

confidence: 99%

“…Household income (minimum wages): ≤1, 2–3, 4–5 and >5 [ 21 ]. In this study, family income was categorized based on the number of minimum wages, with the lowest socioeconomic level, the lowest concentration of income, represented by stratification 1 (one minimum wage), while the highest socioeconomic level, the highest concentration of income, represented by category 5 (five or more minimum wages).…”

Section: Methodsmentioning

confidence: 99%

Magnitude of risk factors for chronic noncommunicable diseases in adolescents and young adults in Brazil: A population-based study

Pedroso,

Pereira,

Cavalcante

et al. 2023

PLoS ONE

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Aim of the study Estimate the magnitude and factors associated with risk factors for chronic noncommunicable diseases in adolescents and young adults in Brazil. Methods Cross-sectional study that analyzed data from the 2019 National Health Survey. The population of interest was adolescents and young adults aged 15 to 24 years. Data were collected through individual interviews during home visits. Dependent variables included major risk factors for chronic noncommunicable diseases. Demographic and socioeconomic characteristics were used as independent variables. Multiple Poisson regression models were used to assess the relationship between independent variables and risk factors. Results A total of 10,460 individuals (5,001 men and 5,459 women) were included. Regardless of sex, the most prevalent risk factors were insufficient fruit and vegetable consumption (92.6%) and leisure-time physical inactivity (43.3%). The prevalence rates of tobacco smokers, alcohol consumption once a month or more, and alcohol abuse were 8.9%, 28.7%, and 18.5%, respectively. Regular consumption of soft drinks and/or artificial juices was described by 17.2%. The prevalence of overweight was 32.5%. Young adults, males, and individuals with lower educational levels, of black race/skin color, with lower household income, and residents of urban areas had a higher prevalence for most risk factors. Differences in the determinants were found for some factors. Inequalities between Brazilian regions were recorded for seven of the nine factors analyzed. The most socioeconomically developed regions had the highest prevalence of most risk factors. The high magnitude of risk factors indicates a potential increase in the burden of chronic noncommunicable diseases in a future scenario for Brazil.

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“…Cardiovascular disease is the leading cause of death in Brazil and worldwide [ 1 , 2 ]. Among cardiovascular disorders, high blood pressure can be highlighted, mainly due to its high prevalence and its role as a risk factor for the development of worsened conditions, such as heart failure and stroke [ 3 ].…”

Section: Introductionmentioning

confidence: 99%

“…The treatment for hypertension includes drug therapy and lifestyle changes [ 2 , 4 ]. Medications employed for the treatment of hypertension play a pivotal role in managing elevated blood pressure.…”

Section: Introductionmentioning

confidence: 99%

Vasodilation and Blood Pressure-Lowering Effect of 3-Demethyl-2-Geranyl-4-Prenylbellidifoline, a Xanthone Obtained from Garcinia achachairu, in Hypertensive Rats

Mariano,

da Silva,

Niero

et al. 2024

Plants

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3-demethyl-2-geranyl-4-prenylbellidifoline (DGP), a natural xanthone isolated from Garcinia achachairu, has previously demonstrated remarkable diuretic and renal protective actions. The present study expands its actions on the cardiovascular system by evaluating its vasorelaxant and blood pressure-lowering effects in spontaneously hypertensive rats (SHRs). Aortic endothelium-intact (E+) preparations of SHRs pre-contracted by phenylephrine and exposed to cumulative concentrations of G. achachairu extract, fractions, and DGP exhibited a significant relaxation compared to vehicle-only exposed rings. The non-selective muscarinic receptor antagonist (atropine), the non-selective inhibitor of nitric oxide synthase (L-NAME), as well as the inhibitor of soluble guanylate cyclase (ODQ) altogether avoided DGP-induced relaxation. Tetraethylammonium (small conductance Ca2+-activated K+ channel blocker), 4-aminopyridine (a voltage-dependent K+ channel blocker), and barium chloride (an influx-rectifying K+ channel blocker) significantly reduced DGP capacity to induce relaxation without the interference of glibenclamide (an ATP-sensitive inward rectifier 6.1 and 6.2 K+ channel blocker). Additionally, administration of DGP, 1 mg/kg i.v., decreased the mean, systolic, and diastolic arterial pressures, and the heart rate of SHRs. The natural xanthone DGP showed promising potential as an endothelium-dependent vasorelaxant, operating through the nitric oxide pathway and potassium channels, ultimately significantly reducing blood pressure in hypertensive rats.

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Factors associated with cardiovascular disease in the Brazilian adult population: National Health Survey, 2019

Cited by 12 publications

References 21 publications

Prevalence and factors associated with multimorbidity in adults in Brazil, according to sex: a population-based cross-sectional survey

Prevalence and factors associated with multimorbidity in adults in Brazil, according to sex: a population-based cross-sectional survey

Magnitude of risk factors for chronic noncommunicable diseases in adolescents and young adults in Brazil: A population-based study

Vasodilation and Blood Pressure-Lowering Effect of 3-Demethyl-2-Geranyl-4-Prenylbellidifoline, a Xanthone Obtained from Garcinia achachairu, in Hypertensive Rats

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