Factors associated with atrial fibrillation in patients with mitral stenosis: A cardiac catheterization study

Moreyra, Abel E.; Wilson, Alan C.; Deac, Radu; Suciu, Ciprian; Kostis, John B.; Ortan, Florin; Kovacs, Tiberiu; Mahalingham, Banu

doi:10.1016/s0002-8703(98)70354-0

Cited by 26 publications

(20 citation statements)

References 16 publications

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“…Stenosis severity and haemodynamic consequences are major determinants of AF in MS,2 but age is also important. Rates of persistent AF are <20% in series in which mean age is <35 years while they range between 30% and 60% when >45 (table 1, figure 1).…”

Section: Pathophysiology Of Af In Msmentioning

confidence: 99%

Management of atrial fibrillation in patients with rheumatic mitral stenosis

Iung

Leenhardt

Extramiana

2018

Heart

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Atrial fibrillation (AF) is frequent in patients with rheumatic mitral stenosis (MS). Pressure overload leads to marked structural and electrical remodelling of left atrium. The frequency of persistent AF increases with age and paroxysmal, asymptomatic, AF seems even more frequent. The occurrence of AF worsens the haemodynamic tolerance of MS and markedly increases the risk of thromboembolic events. AF has a negative impact on the natural history of MS and on its outcome after commissurotomy. The respective indications of rhythm and rate control should be adapted to patient characteristics, particularly the consequences of MS, and take into account the high risk of recurrence of AF. Oral anticoagulant therapy is mandatory when AF complicates MS, regardless of its severity and CHA2DS2-VASc score. Non-vitamin K antagonists oral anticoagulants are not recommended in moderate-to-severe MS due to the lack of data. Percutaneous mitral commissurotomy does not appear to prevent the occurrence of AF in MS but should be considered as the first-line therapy when AF is associated with severe symptomatic MS, followed by the discussion of cardioversion or ablation. AF ablation should be considered in patients with mitral disease requiring intervention, but the ideal timing and techniques are difficult to determine due to the lack of appropriate specific randomised trials in patients with MS.

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Section: Pathophysiology Of Af In Msmentioning

confidence: 99%

Management of atrial fibrillation in patients with rheumatic mitral stenosis

Iung

Leenhardt

Extramiana

2018

Heart

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“…Patients with MS commonly develop AF caused by LAE in response to valve obstruction as well as inflammatory and fibrotic changes caused by the rheumatic process. 14 In our study, 23 patients (57.5%) achieved good outcome (defined as an mRS score ≤ 2) at 3 months. Mortality at 3 months was 7.5%.…”

Section: Discussionmentioning

confidence: 51%

Predictors of Ischemic Stroke in Rheumatic Heart Disease

Gupta

Bhatia

Sharma

et al. 2015

Journal of Stroke and Cerebrovascular Diseases

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“…Severe mitral stenosis leads to pulmonary hypertension, right ventricular failure and atrial remodeling. This situation is more evident in cases where mitral valve area was <1 cm 2 and pulmonary vascular resistance was > 5 wood unit 12,13,14 . In Framingham study, it has been reported that, the incidence of atrial fibrillation in right ventricular dilatation increased two-fold 15 .…”

Section: Discussionmentioning

confidence: 97%

Mitral stenozda sol atrial volüm indexi ve Sağ ventrikül dilatasyonunun atrial fibrilasyon için prediktif değeri

Yıldız¹,

Karakurt²,

Amikoğlu³

2014

Cukurova Medical Journal

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Purpose:To examine the predictive value of left atrial volume index (LAVI) and right ventricular dilatation in mitral stenosis (MS) for atrial fibrillation (AF) and to determine the cut-off value. Materials and Methods: 14 men, 92 women, a total of 106 cases between the ages of 23-86 (mean: 50.7 ± 12.7) with mitral stenosis were included in the study. All echocardiographic assessments were performed according to the criteria of American Society of Echocardiography (ASE). Patients were divided into two groups as AF and normal sinus rhythm (NSR). 39 patients with AF were classified as AF group and 67 patients with normal sinus rhythm were classified as NSR group. The demographic, clinical, echocardiographic characteristics of these two groups were compared. For the statistical analysis of datas, Kolmogorov-Smirnov, T-test, Mann-Whitney-U test and ROC analysis were used. Results: In mitral valve stenosis, left atrial volume index and right ventricular diastolic diameter increase. LAVI cut-off value for atrial fibrillation is 40,74 ml/m 2 , the sensitivity and specificity of it was found to be as 80% and 80.6%, respectively (PPV = 69.0%, NPV = 88.5%). Cut-off value of right ventricular diastolic diameter (RVDD) for atrial fibrillation is 36.7 mm, the sensitivity and specificity of it was found to be as 62.9% and 59.7%, respectively (PPV = 46.0%, NPV = 75.5%).

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Factors associated with atrial fibrillation in patients with mitral stenosis: A cardiac catheterization study

Cited by 26 publications

References 16 publications

Management of atrial fibrillation in patients with rheumatic mitral stenosis

Management of atrial fibrillation in patients with rheumatic mitral stenosis

Predictors of Ischemic Stroke in Rheumatic Heart Disease

Mitral stenozda sol atrial volüm indexi ve Sağ ventrikül dilatasyonunun atrial fibrilasyon için prediktif değeri

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