Factors associated with anxiety disorder comorbidity

Davies, Molly R.; Glen, Kiran; Mundy, Jessica; Kuile, Abigail ter; Adey, Brett N.; Armour, Chérie; Assary, Elham; Coleman, Jonathan R. I.; Goldsmith, Kimberley; Hirsch, Colette R.; Hotopf, Matthew; Hübel, Christopher; Jones, Ian; Kalsi, Gursharan; Krebs, Georgina; McIntosh, Andrew M.; Morneau‐Vaillancourt, Geneviève; Peel, Alicia J.; Purves, Kirstin; Lee, Sang Hyuck; Skelton, Megan; Smith, Daniel J.; Veale, David; Walters, James; Young, Katherine S.; Zvrskovec, Johan; Breen, Gerome; Eley, Thalia C.

doi:10.1016/j.jad.2022.11.051

Cited by 7 publications

(4 citation statements)

References 54 publications

(76 reference statements)

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“…Third, although our total sample included 14 994 patients, we were restricted by sample size to investigating associations between relatively prevalent conditions. As such, we cannot comment on granular relationships between specific diagnoses including distinctions between depression or anxiety disorders, among depression or anxiety phenotypes, or among patients who may have more than one anxiety disorder (Davies et al, 2023; Klein Hofmeijer-Sevink et al, 2012). Fourth, our analyses focused on differences between depression and anxiety and did not include a control group.…”

Section: Discussionmentioning

confidence: 99%

Phenotypic distinctions in depression and anxiety: a comparative analysis of comorbid and isolated cases

et al. 2023

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Background Anxiety and depression are frequently comorbid yet phenotypically distinct. This study identifies differences in the clinically observable phenome across a wide variety of physical and mental disorders comparing patients with diagnoses of depression without anxiety, anxiety without depression, or both depression and anxiety. Methods Using electronic health records for 14 994 participants with depression and/or anxiety in the Mayo Clinic Biobank, a phenotype-based phenome-wide association study (Phe2WAS) was performed to test for differences between these groups across a broad range of clinical diagnoses observed in the electronic health record. Additional analyses were performed to determine the temporal sequencing of diagnoses. Results Compared to patients diagnosed only with anxiety, those diagnosed only with depression were more likely to have diagnoses of obesity (OR 1.75; p = 1 × 10−27), sleep apnea (OR 1.71; p = 1 × 10−22), and type II diabetes (OR 1.74; p = 9 × 10−18). Compared to those diagnosed only with depression, those diagnosed only with anxiety were more likely to have diagnoses of palpitations (OR 1.91; p = 2 × 10−25), benign skin neoplasms (OR 1.61; p = 2 × 10−17), and cardiac dysrhythmias (OR 1.45; p = 2 × 10−12). Patients with comorbid depression and anxiety were more likely to have diagnoses of other mental health disorders, substance use disorders, sleep problems, and gastroesophageal reflux relative to isolated depression. Conclusions While depression and anxiety are closely related, this study suggests that phenotypic distinctions exist between depression and anxiety. Improving phenotypic characterization within the broad categories of depression and anxiety could improve the clinical assessment of depression and anxiety.

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Section: Discussionmentioning

confidence: 99%

Phenotypic distinctions in depression and anxiety: a comparative analysis of comorbid and isolated cases

et al. 2023

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“…Anxiety is usually conceptualized as an adverse emotional state to result in distress, anger, muscular tension, and hypertension ( Farber, 1948 ; Davies et al, 2023 ). Nevertheless, moderate anxiety can induce physiological responses in the body and brain, amplifying vigilance and ameliorating performance and reaction time in competitive arenas or sporting contexts ( Belon, 2019 ).…”

Section: Introductionmentioning

confidence: 99%

A study on the impact of systematic desensitization training on competitive anxiety among Latin dance athletes

Chen,

Zhou,

Gong

et al. 2024

Front. Psychol.

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ObjectiveIn the domain of competitive events, Latin dance athletes have always suffered competitive anxiety, which is a prevalent and prevailing psychological facet, in pre-, intra-, and post-competitive engagements. Usually, the implementation of systematic desensitization training is an efficacious approach to reduce competitive anxiety levels in routine sports to fortify psychological resilience of athletes (like swimming, volleyball, and basketball). This study focuses on the effect of systematic desensitization training on competition anxiety in the training of Latin dancers to establish good mental ability and promote the competitive ability of athletes.MethodologyThe “Sports Competition Anxiety Test Questionnaire” was used to evaluate and classify the competitive anxiety levels of 150 Latin dance athletes. Then, the top 48 participants were selected (24 in the intervention cohort and 24 in the non-intervention cohort) as the study participants after stratifying anxiety score levels from the highest to the lowest. The intervention group was treated with an 8-week psychological intervention by employing systematic desensitization training techniques (encompassing imagery desensitization and in vivo desensitization). The anxiety levels of the subjects were quantified by employing the “Sport Competition Trait Anxiety Inventory” (CCTAI-C) and the “Competitive State Anxiety Inventory” (CSAI-2) to scrutinize the efficacy of systematic desensitization training in regulating competitive anxiety levels among Latin dance athletes.ResultsAfter applying systematic desensitization training, the intervention group displayed a notable reduction in sport cognitive trait anxiety. Specifically, there was a decrease of 29.37% in social evaluation anxiety, 20.31% in competition preparation anxiety, 16.98% in performance anxiety, 25.16% in failure anxiety, 34.47% in opponent’s ability anxiety, and 25.16% in injury anxiety. Moreover, for competitive state anxiety, cognitive state anxiety and somatic state anxiety decreased by 39.19 and 21.43%. The state self-confidence increased by 14.42%.ConclusionThe result indicated that systematic desensitization training not only mitigates anxiety but also positively intervenes in sports-related anxiety. Moreover, systematic desensitization training can significantly diminish competitive anxiety among Latin dance athletes to bolster confidence during competitions. Integrating desensitization training into the regular regimen of Latin dance practice has the potential to fortify dancers’ psychological resilience against anxiety.

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“…The fear and anxiety associated with the potential infection can have detrimental effects, leading to psychological disorders and stress. In the short term, fear and stress trigger the hypothalamus in the brain, resulting in the release of cortisol hormone from the adrenal cortex and activation of sympathetic nerves throughout the body, which are beneficial for coping with stressful factors (Lakhan et al, 2020;Mahfud & Gumantan, 2020;Davies et al, 2023). However, if prolonged fear, stress, and the associated physiological response, including elevated cortisol levels and sympathetic activation persist, they can have deleterious effects, compromising the immune system's functioning and reducing the body's ability to combat diseases, including COVID-19 (Asadi et al, 2021).…”

Section: Introductionmentioning

confidence: 99%

Comparing the Effectiveness of Guided Imagery and Lazarus Multimodal Therapy on COVID-19 Anxiety and Life Expectancy in People Recovered From COVID-19

Farzin,

Amiri Majd,

Ghamari

2024

PCP

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Given the well-established and irreversible psychological consequences associated with the COVID-19 disease, it becomes imperative to develop interventions tailored to address these effects and comprehensively evaluate their efficacy in promoting the mental well-being of individuals who have successfully recuperated from COVID-19. The current investigation primarily ascertained and juxtaposed the efficacy of guided imagery and Lazarus multimodal therapy in alleviating COVID-19-induced anxiety and enhancing life expectancy among post-COVID-19 patients Methods: The present study employed a semi-experimental design, encompassing the objectives, application, and research methodology. Specifically, a pre-test-post-test design with a control group was utilized, incorporating a three-month follow-up period. The statistical population comprised individuals who had recovered from COVID-19 and were residing in Tehran City, Iran, in 2021. Participants were selected from various government hospitals in Tehran who received treatment for COVID-19. A total of 45 participants were randomly assigned into three groups: the guided imagery group (15 participants), the Lazarus multimodal therapy group (15 participants), and the control group (15 participants), using the lottery method. The experimental groups underwent 10 sessions of 90 minutes each, wherein guided imagery and Lazarus multimodal therapy interventions were respectively administered. The control group did not receive any form of training or intervention. The research instruments employed in this study were the COVID-19 Anxiety Questionnaire (CDAS, 2020) developed by Alipour, Gadami, Alipour, and Abdulzadeh, and Miller's Life Expectancy Questionnaire (MLEQ, 1998). Data were analyzed using covariance analysis in SPSS software, version 26. Inferential analysis was performed with alpha 0.05 Results:The findings of the study revealed that both guided imagery and Lazarus multimodal therapy demonstrated effectiveness in mitigating COVID-19 anxiety (F=11.16, P=0.000) and enhancing life expectancy (F=5.49, P=0.008) among individuals who had recovered from COVID-19 (P<0.05). Furthermore, no significant difference was observed between the effects of these interventions on the aforementioned variables. Conclusion:Based on the research findings, the educational packages developed in this study hold the potential for utilization in reducing COVID-19 anxiety and enhancing life expectancy among individuals amidst the ongoing pandemic outbreak. These packages offer valuable resources for addressing and managing anxiety related to COVID-19, thereby contributing to improved psychological well-being and overall life expectancy during this challenging period.

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Factors associated with anxiety disorder comorbidity

Cited by 7 publications

References 54 publications

Phenotypic distinctions in depression and anxiety: a comparative analysis of comorbid and isolated cases

Phenotypic distinctions in depression and anxiety: a comparative analysis of comorbid and isolated cases

A study on the impact of systematic desensitization training on competitive anxiety among Latin dance athletes

Comparing the Effectiveness of Guided Imagery and Lazarus Multimodal Therapy on COVID-19 Anxiety and Life Expectancy in People Recovered From COVID-19

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