Factors associated with anxiety and depression in patients with erectile dysfunction: a cross-sectional study

Xiao, Yang; Xie, Tongjin; Peng, Jingxuan; Long, Jianhong; Yang, Minghui; Zhu, Haiyan; Yang, Jianfu

doi:10.1186/s40359-023-01074-w

Cited by 12 publications

(10 citation statements)

References 45 publications

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“…Accordingly, sexual dysfunctions could lead to anxious status, which can increase the likelihood of future sexual failure, creating a vicious circle. 38 Consequently, it is not surprising that in our analysis men presenting with concomitant ED and uOD, with respect to ED-only patients, more frequently reported anxiety and had higher rates of depressive symptoms and lower scores in all IIEF domains, thus indicating the potential disruption of the overall sexual response cycle. 1 This emerges to be of particular importance in the clinical practice because the combination of embarrassment and mood deflection leaves men even more fragile, with different expectations and probably less prone to follow further physicians' suggestions.…”

Section: Discussionmentioning

confidence: 72%

“…Trovão and Serefoglu 36 showed that OD in depressed men could be a consequence of a disrupted desire and/or arousal phase; once sexual arousal is impeded, orgasm and ejaculation will not be initiated. Accordingly, sexual dysfunctions could lead to anxious status, which can increase the likelihood of future sexual failure, creating a vicious circle 38 . Consequently, it is not surprising that in our analysis men presenting with concomitant ED and uOD, with respect to ED‐only patients, more frequently reported anxiety and had higher rates of depressive symptoms and lower scores in all IIEF domains, thus indicating the potential disruption of the overall sexual response cycle 1 .…”

Section: Discussionmentioning

confidence: 80%

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Unrecognised orgasmic phase disorders in men presenting with new‐onset erectile dysfunction—Findings from a real‐life, cross‐sectional study

et al. 2023

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BackgroundOrgasmic phase disorders in men worsen the burden of erectile dysfunction on sexual satisfaction.ObjectivesTo investigate the prevalence of and predictors of unreported orgasmic phase disorder in a cohort of men looking for their first urological assessment for new‐onset erectile dysfunction in a real‐life setting.Materials and methodsData from 1107 heterosexual, sexually active men consecutively assessed for new‐onset erectile dysfunction were analysed. Throughout a comprehensive medical and sexual history, all patients were asked to self‐report any orgasmic phase disorder and to complete the International Index of Erectile Function and the Beck's Inventory for Depression (depressive symptoms scored as Beck's Inventory for Depression ≥11). Men self‐reporting orgasmic phase disorder during the interview were excluded from further analyses. The median value of the International Index of Erectile Function‐orgasmic function domain was arbitrarily used to categorise men with (International Index of Erectile Function‐orgasmic function ≤5) and without unreported orgasmic phase disorder (International Index of Erectile Function‐orgasmic function >5). Circulating hormones were measured in every patient. Descriptive statistics and logistic regression models were used to test the association between clinical variables and unreported orgasmic phase disorder.ResultsOf 1098 patients with non‐self‐reporting orgasmic phase disorder, 314 (28.6%) had International Index of Erectile Function‐orgasmic function ≤5. Patients with erectile dysfunction + unreported orgasmic phase disorder were older (median [interquartile range]: 58 [44–66] years vs. 51 [40–60] years), had higher body mass index [25.8 (23.7–28.1) kg/m2 vs. 25.2 (23.3–27.4) kg/m2], higher prevalence of type 2 diabetes (36 [11.5%] vs. 45 [5.7%]) and lower International Index of Erectile Function‐erectile function scores (6 [2–10] vs. 18 [11–24]) than men with erectile dysfunction‐only (all p < 0.05). Patients with erectile dysfunction + unreported orgasmic phase disorder depicted higher rates of severe erectile dysfunction (75.5% vs. 25%) and Beck's Inventory for Depression ≥11 (22.6% vs. 17.9%) (all p < 0.05). In the multivariable logistic regression analysis, older age (odds ratio: 1.02) and lower International Index of Erectile Function‐erectile function scores (odds ratio: 0.83) were independently associated with unreported orgasmic phase disorder (all p < 0.05).ConclusionsAlmost one in three men seeking first medical help for erectile dysfunction depicted criteria suggestive of unreported orgasmic phase disorder. Men with unreported orgasmic phase disorder were older and had higher rates of severe erectile dysfunction and concomitant depressive symptoms. These real‐life findings outline the clinical relevance of a comprehensive investigation of concomitant sexual dysfunction in men only complaining of erectile dysfunction to more effectively tailor patient management.

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Section: Discussionmentioning

confidence: 72%

Section: Discussionmentioning

confidence: 80%

Unrecognised orgasmic phase disorders in men presenting with new‐onset erectile dysfunction—Findings from a real‐life, cross‐sectional study

et al. 2023

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“… 46 However, reverse causality could also exist; that is, ED can cause mental health symptoms and vice versa. 47 In a systematic review, Liu et al estimated that men with depression had a 2.92-times higher probability of experiencing ED (odds ratio, 2.92; 95% CI, 2.37-3.60). 48 In Chinese men aged 22 to 50 years, Zhang et al found a higher proportion of ED in those with depressive and anxious symptoms ( P = .002).…”

Section: Discussionmentioning

confidence: 99%

Irritable bowel syndrome and erectile dysfunction in medical students at a Peruvian university: an analytical cross-sectional analysis

Valladares-Garrido,

Zapata-Castro,

Quiroga-Castañeda

et al. 2024

Sexual Medicine

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Background There is inconclusive evidence regarding the role of irritable bowel syndrome (IBS) in the development of erectile dysfunction (ED), especially among medical students due to high academic stress. Aim To determine the association between IBS and ED in medical students from a Peruvian university in 2022. Methods An analytical cross-sectional study was conducted with secondary data analysis on 133 medical students from a university in northern Peru during the 2021-II academic semester. The dependent variable was ED as measured with the 5-item International Index of Erectile Function, and the exposure variable was IBS as assessed with the Rome IV–Bristol questionnaire. Outcomes The results were the prevalence rates of IBS and ED and the association of these variables. Results Of the 133 medical students surveyed, the median age was 22 years (IQR, 19-24). The median score on the 5-item International Index of Erectile Function was 21 (IQR, 10-24). The prevalence of ED was 38.4% (95% CI, 30.05%-47.17%). Among the medical students 3% and 9% displayed moderate and severe ED, respectively, and 24.8%, 13.5%, and 24.1% showed moderate depressive, anxious, and severe symptoms. An overall 10.5% had IBS. Medical students with IBS had a 108% higher prevalence of ED than those without the syndrome (prevalence ratio, 2.08; 95% CI, 1.06-4.06). Other confounding variables were not significantly associated (P > .05). Clinical Implications The results underline the importance of comprehensive sexual and mental health assessment, with an emphasis on the relationship between IBS and ED in medical students. Strengths and Limitations Strengths include the use of validated and reliable instruments and rigorous biostatistical methods, and this is the first Peruvian investigation to explain the association between IBS and ED in medical students. Limitations include the cross-sectional design and nonprobability sampling, and there may be bias in applying the instruments. Conclusion This study reveals a significant association between IBS and a higher prevalence of ED in these students.

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“…In addition, sexual dysfunction itself can affect mental health [112]. and administer individualized treatment in a timely manner [113].…”

Section: Psychiatric Disordersmentioning

confidence: 99%

What Affects Male Sexual Activity: A Comprehensive Review

Peng,

Xiang,

Yang

et al. 2023

Health

Self Cite

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The fundamental importance of sex lies in the need for reproduction and species continuity. For humans, sexual expression is an important source of physical pleasure and emotional intimacy. Healthy sexual expression is closely related to well-being, health and overall quality of life in both men and women. Sexual activity is also considered an important determinant of quality of life. At present, questions about sex are still largely ignored in routine consultations in almost all medical specialties. The factors affecting sexual activity are complex and can be divided into the influence of bio-psycho-sociological factors. Biological influences include anthropometric parameters, sexual function, lifestyle, neuroendocrine system, and diseases; psychological influences include psychological status, mental illness, and sexual attitudes; sociological influences include factors such as marriage, occupation, and economic status. With the epidemic and outbreak of Coronavirus disease 2019 (COVID-19), people's way of life and work has changed, which also has a great impact on sexual activities. This article will provide a systematic review of factors related to male sexual activity.

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Factors associated with anxiety and depression in patients with erectile dysfunction: a cross-sectional study

Cited by 12 publications

References 45 publications

Unrecognised orgasmic phase disorders in men presenting with new‐onset erectile dysfunction—Findings from a real‐life, cross‐sectional study

Unrecognised orgasmic phase disorders in men presenting with new‐onset erectile dysfunction—Findings from a real‐life, cross‐sectional study

Irritable bowel syndrome and erectile dysfunction in medical students at a Peruvian university: an analytical cross-sectional analysis

What Affects Male Sexual Activity: A Comprehensive Review

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