Factors associated with adherence to Antiretroviral Therapy (ART) among adult people living with HIV and attending their clinical care, Eastern Ethiopia

Abstract

BackgroundTo attain a successful treatment outcome, Antiretroviral Therapy (ART) treatment for people living with HIV requires more than 95 % adherence level. The adherence level varies depending on different population contexts. Thus, the objective of this study was to investigate ART adherence level among HIV positive patients attending their clinical care in public health facilities in Harar and Dire Dawa, Eastern Ethiopia.MethodsWe conducted a cross-sectional study among 626 ART attendees. Data were collected using a structured questionnaire with a face-to-face interview. ART adherence was considered when taking all antiretroviral treatment in a correctly prescribed doses at a right time (no dose missed or delayed for greater than or equal to 90 min) in the week prior to the study. Multivariable logistic analysis was applied to examine the association between the dependent and independent variables. Statistical significance was set at p-value <0.05.ResultsThe level of ART adherence was 85 %. Adherence was more likely among patients of 35–44 years (AOR = 2.39; 95 % CI = 1.15–5.01), had monthly income of 501.00–999.00 Ethiopian Birr (ETB) (AOR = 6.73; 95 % CI = 2.71–16.75), no history of opportunistic infection (AOR = 2.81; 95 % CI = 1.47–5.36), and had good family support (AOR = 2.61; 95 % CI = 1.45–4.72). However, those who did not disclose their sero-status (AOR = 0.45; 95 % CI = 0.21–0.97) and did experience depression (AOR = 0.36; 95 % CI = 0.21–0.61) were less likely adherent than their counter parts.ConclusionsThe level of ART adherence was sub-optimal. Concerted and collaborative efforts through effective and efficient interventions are needed in view of the identified factors in order to improve the adherence level.

Correlates of ART Adherence among Pregnant and Breastfeeding Mothers Initiated on Life Long ART for People Living with HIV/AIDS (LLAPLA) in One Public Health Unit in the Hhohho Region

“…In order to achieve this, health workers should be equipped on how to be good listeners, and communicate nicely with ART patients when providing counselling and care to pregnant mothers living with HIV. Similar findings have been observed in other studies [20,21]. In this study having a problem of forgetfulness negatively correlated to adherence and similar findings were observed in other studies [24,25].…”

“…Having a monthly income of 501.00-999.00 Ethiopian Birr (ETB) significantly (AOR=6.73; 95% CI=2.71-16.75) associated to adherence [20]. Differences in the findings could be due to differences in the population of the study, that is, this study focused only on mothers attending ANC and post natal services.…”

Spectrum of Opportunistic Disease and Associated Factors Among Patients Attending ART Clinic, Nekemte Specialized Hospital, Western Ethiopia

“…In current suggestion, at least 95% of ART adherence level is needed to overwhelm viral replication, show clinical improvement and better CD4 count (25). Despite, the level of adherence is in agreement with recommended level; the result of current level of adherence was comparably higher than the documented nding of study conducted in Eastern Ethiopia (85%) (20) and…”

“…Various literatures suggested that, history of opportunistic infections, Hgb levels, WHO clinical staging, CD4 counts, taking past OI prophylaxis, ART drug adherence, monthly income and occupation were identi ed as predictors of developing OIs among HIV infected patients (14)(15)(16)19,20). However, methodological difference and variation of duration of HART were observed across these studies.…”

Erratum to: Factors associated with adherence to Antiretroviral Therapy (ART) among adult people living with HIV and attending their clinical care, Eastern Ethiopia

“…It has come to the publisher’s attention that in the original article [ 1 ], Table 3 was incorrectly formatted. The correct formatting of the table has been updated in the original article, and published in this Erratum for quick reference, see Table 1 .…”