Factors associated with acute medication overuse in chronic migraine patients

Zukerman-Guendler, Vera

doi:10.1590/s0004-282x2008000400040

Cited by 1 publication

(2 citation statements)

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“…A similar study focusing on psychiatric comorbidities revealed that lifetime anxiety and mood disorders were more prevalent in MOH patients compared to the control group [18]. Furthermore, this study also examined personality disorders and a family history of substance use, which were found to increase the risk of MOH development [18,19]. Another study investigating the progression of migraines to MOHs reported a higher prevalence of anxiety, depression, mood disorders, and psychoactive substance use among individuals with an MOH [20,21].…”

Section: Discussionmentioning

confidence: 78%

“…However, no significant correlations were found for a history of allergies, anxiety, depression, bruxism, or fibromyalgia. A similar study focusing on psychiatric comorbidities revealed that lifetime anxiety and mood disorders were more prevalent in MOH patients compared to the control group [18]. Furthermore, this study also examined personality disorders and a family history of substance use, which were found to increase the risk of MOH development [18,19].…”

Section: Discussionmentioning

confidence: 84%

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Complicated Form of Medication Overuse Headache Is Severe Version of Chronic Migraine

Göçmez Yılmaz,

Ghouri,

Özdemir

et al. 2024

JCM

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Background: MOH (medication overuse headache) is regarded as a complication of chronic migraines (CMs), with a general acknowledgment of reciprocal triggering between these two conditions. The present study aims to investigate the clinical parameters of relevance for the development of MOH among patients with CM, as well as for the subtype classification of MOHs. Method: We compared two groups of CM patients, with and without MOH, separated based on their demographic data and migraine characteristics. A subgroup of MOH accompanied by psychiatric co-morbidities (depression, anxiety, sleep disorder) was delineated, and the clinical features of relevance for the progression of MOH into the complicated state were evaluated. Results: The study revealed a higher prevalence of a family history of migraine in both the MOH and potentially complicated MOH subgroups (p < 0.001, p = 0.036), along with a higher prevalence of bilateral pain localization (p = 0.033, 0.021). Symptoms commonly associated with migraines, such as nausea, vomiting, photophobia, phonophobia, and osmophobia, were more common in both the MOH and potentially complicated MOH subgroups (p < 0.05). Furthermore, a positive correlation was found for the frequency (p < 0.001) and severity (p = 0.010) of migraine attacks and the duration of headaches (p = 0.007), atopy (p = 0.017), sleep disturbances (p = 0.011), and emotional stress (p = 0.022) in the MOH group. Conclusion: We found a positive correlation between the prevalence of MOH among patients with CM and a family history of migraines, higher frequency and intensity of headaches, bilateral manifestation, sleep disturbances, and emotional stress. Moreover, symptoms accompanying migraines were found to be more prevalent in individuals with MOH and potentially complicated MOH.

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