Factors affecting visual outcomes after treatment of infectious endophthalmitis in northeastern Thailand

Yospaiboon, Yosanan; Intarapanich, Anocha; Laovirojjanakul, Wipada; Ratanapakorn, Tanapat; Sinawat, Suthasinee; Sanguansak, Thuss; Bhoomibunchoo, Chavakij

doi:10.2147/opth.s160758

Cited by 13 publications

(16 citation statements)

References 23 publications

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“…The results obtained for pathogenic bacteria were consistent with the findings of most reports [2,14,18,19]. We obtained anterior aqueous humor and or vitreous fluid for bacterial culture from 316 patients, and the culture-positive rate was 44.62%.…”

Section: Discussionsupporting

confidence: 90%

Clinical analysis and predictive factors associated with improved visual acuity of infectious endophthalmitis

et al. 2020

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Background: To describe the clinical characteristics and analyze the predictive factors associated with improved visual acuity of 359 patients with infectious endophthalmitis. Methods: This study retrospectively analyzed 359 eyes of 359 patients with infectious endophthalmitis from January 2014 to December 2018. The findings summarized some epidemiological characteristics of these patients, including age, sex, occupation, patient visit time, etiology, causative organisms, therapy, and best-corrected visual acuity. Multivariate logistic regression was performed to predict the relative factors of improved visual acuity (VA). Results: Overall, 283 (78.83%) patients were male. The mean age was 48.0 ± 18.27 years. Ocular trauma, especially open globe injuries (246, 68.5%) was the most common etiology of infectious endophthalmitis in this study. The etiologies of infectious endophthalmitis were open globe injuries (68.5%), intraocular surgery (22.6%), and corneal ulcer-associated (6.7%) and endogenous causes (2.2%). In the etiology classification and visual acuity improvement group, had statistically significant differences in factors such as age, sex, patient visit time, pre-therapy visual acuity, etc. The average Logarithm of the Minimum Angle of Resolution (logMAR) best-corrected visual acuity on pretherapy was 2.28 ± 0.60, and it had significantly improved to 1.67 ± 0.83 post-therapy (P < 0.05). Logistic regression analysis showed that visit time > 7 day (P = 0.034, OR = 0.522, 95% CI: 0.286-0.953), pre-therapy VA ≦logMAR 2.3 (P = 0.032, OR = 1.809, 95% CI: 1.052-3.110), post-surgical (vs. posttraumatic; P = 0.023, OR = 2.100, 95% CI: 1.109-3.974), and corneal ulcer-associated etiologies (vs. posttraumatic; P = 0.005, OR = 0.202, 95%CI: 0.066-0.621) were significantly associated with improved visual acuity after adjusting for possible confounding factors. Conclusions: Among the patients with infectious endophthalmitis, middle-aged male, especially farmers and workers, accounted for a large proportion. Open globe injuries were the main cause and the gram-positive bacteria were the major causative organisms. The final visual outcomes seemed to vary according to the type of endophthalmitis, but early treatment and good initial visual acuity were important factors for visual acuity improvement.

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Section: Discussionsupporting

confidence: 90%

Clinical analysis and predictive factors associated with improved visual acuity of infectious endophthalmitis

et al. 2020

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“…In our study 67.5% had total cataract which matches with other studies which had 74% total cataract. 9,10 In our study, BCVA of 6/18-6/6 was seen in 56% cases after surgical treatment, 6/36-6/24 in 24% cases and 8% cases had BCVA equal to or less than 6/60. Some studies achieved visual acuity of >6/18 after surgery, and suggested that the initial visual acuity and patient age were predictors.…”

Section: Discussionsupporting

confidence: 47%

Evaluation of the factors affecting visual prognosis in patients with traumatic cataract

Dhanya¹,

Abraham²,

Nair³

2020

Int J Res Med Sci

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Background: Ocular trauma is a major cause of visual impairment throughout the world, although little is known about the factors that affect the visual outcome in traumatic cataract in developing countries. The objective of the study was to find out the associated ocular injuries and the factors affecting final visual outcome of patients with traumatic cataract.Methods: This prospective-hospital based study was conducted on 50 patients of traumatic cataract in the department of ophthalmology government medical college, Ernakulam, from January 2009 to December 2011. Patients were managed with lens extraction and intraocular lens implantation. Regular follow up of patients was done and best corrected visual acuity (BCVA) and post-operative complications were assessed at the end of six months.Results: Our study showed that majority (64%) of patients were in the age group of <40 years with male preponderance. visual outcome was significantly better in younger age group (<20 years) than the older group (>20 years) (p=0.03). There was no significant difference in final visual outcome of traumatic cataracts caused by penetrating or blunt trauma (p=0.73). Corneal tear was most common associated ocular damage followed by uveitis, lens matter in anterior chamber.Conclusions: Age of the patient affects final visual outcome after surgical treatment of traumatic cataract but type of trauma (blunt/penetrating) had no significant effect on final visual outcome. Corneal tear was most common associated ocular damage.

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“…Usually, EKPE patients are adults [8, 12, 23, 24]. Although the median age in our study was 51.3 years, the youngest patient in our case series was only 3 years old.…”

Section: Discussionmentioning

confidence: 61%

Endogenous Endophthalmitis Caused by <b><i>Klebsiella pneumoniae</i></b>: A Ten-Year Retrospective Study in Western China

et al. 2020

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The aim of this study was to analyse the clinical features, microbiology results, management and outcomes of patients with endogenous endophthalmitis caused by Klebsiella pneumoniae in western China. Methods: A retrospective review of medical records of 10 eyes in 10 subjects diagnosed with endogenous K. pneumoniae endophthalmitis from January 2008 to December 2018 was undertaken. Results: The top 3 predisposing medical conditions included diabetes mellitus (50%), malignancy (20%) and cardiac stent implantation (10%). Extraocular infective foci were mainly found in the liver (40%), lungs (20%) and kidneys (10%). The positive culture rate was 85.71% (6/7) in vitreous samples, 83.33% (5/6) in blood samples and 100% (4/4) in body fluid samples. Only 20% of the patients, who had good initial visual acuity (VA) better than hand movement (HM), achieved a final VA better than 1.0 (log MAR). The mortality rate was 10%. Conclusions: Though the prognosis of endogenous K. pneumoniae endophthalmitis is often poor, patients with an initial VA better than HM may have a good prognosis under comprehensive treatments, including vitrectomy, systemic sensitive antibiotic injection and drainage of the primary infection loci.

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Factors affecting visual outcomes after treatment of infectious endophthalmitis in northeastern Thailand

Cited by 13 publications

References 23 publications

Clinical analysis and predictive factors associated with improved visual acuity of infectious endophthalmitis

Clinical analysis and predictive factors associated with improved visual acuity of infectious endophthalmitis

Evaluation of the factors affecting visual prognosis in patients with traumatic cataract

Endogenous Endophthalmitis Caused by <b><i>Klebsiella pneumoniae</i></b>: A Ten-Year Retrospective Study in Western China

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