Factors affecting therapeutic compliance: A review from the patient&amp;rsquo;s perspective

Jin, Jing; Sklar, Grant E.; Oh, Vernon M S; Li, Shu Chuen

doi:10.2147/tcrm.s1458

Cited by 842 publications

(304 citation statements)

References 149 publications

(270 reference statements)

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“…The possible reason might be that older people have more concern about their health than younger patients. 20 The mean duration of hypertension was 5.68±4.37 years. A significantly strong negative correlation (r=-0.133, p=0.012) was found between total treatment compliance score and duration of hypertension ( Figure 2).…”

Section: Resultsmentioning

confidence: 98%

Compliance to antihypertensive medication: a cross-sectional study in Aligarh

Khwaja

Ansari

Mehnaz

2017

Int J Community Med Public Health

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Background: Hypertension is a global public health issue. Hypertensive heart disease is one of the top ten leading causes of death in the world. It was responsible for an estimated 1.1 million deaths worldwide in 2012. To prevent some of the complications of hypertension regular intake of the prescribed treatment in the form of medicines (pills) is essential. Poor compliance to anti-hypertensive therapy is usually associated with bad outcome of the disease and wastage of limited health care resources. With these viewpoints the study aimed to assess the level of compliance of hypertensive patients to their anti-hypertensive medications and to determine the socio-demographic correlates of compliance. Methods: This was community based cross sectional study conducted in urban and rural areas in Aligarh. A total of 350 hypertensive patients were selected using simple random sampling. A pretested semi-structured questionnaire was used. Compliance was measured by Morisky 8-item Medication Adherence scale. Analysis was done using proportions and Chi-square test. Results: The overall compliance of study population was 23.7%. It was found to be significantly associated with gender, education, social class and associated co morbidities. Education, higher social class and duration of hypertension were found to be the main facilitators to adherence. The barriers to adherence were cost of drug and more number of pills per day. Conclusions: Patient education, family counselling and social support networks should be strengthened in health promotion programs in order to enhance compliance of hypertensive patients with the therapeutic regimen and to improve their quality of life.

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Section: Resultsmentioning

confidence: 98%

Compliance to antihypertensive medication: a cross-sectional study in Aligarh

Khwaja

Ansari

Mehnaz

2017

Int J Community Med Public Health

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“…Though non-adherence to antihypertensive treatment is a significant problem in CHD management few studies on medication adherence have been conducted in developing countries [61]. Moreover, the majority of these studies were conducted in hospital and clinical settings.…”

Section: Discussionmentioning

confidence: 99%

A Systematic Review of Factors Influencing Medication Adherence to Hypertension Treatment in Developing Countries

Dhar¹,

Dantas²,

Ali³

2017

OJEpi

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Background: Coronary heart disease (CHD), a complication of hypertension, is one of the most important and common causes of morbidity, hospitalisation, and mortality among hypertensive population. In recent decades, increased urbanisation and changes to lifestyle, diet and physical activity in developing countries have led to a major increase in the population incidence of chronic diseases including CHD. Poor medication adherence is one of the leading causes of failure to achieve hypertension control. The objective of this systematic review is to describe the prevalence of non-adherence to antihypertensive medications among hypertensive population in developing countries and identify factors associated with it. Methods: A literature search was conducted using the following scholarly electronic databases: Proquest, PubMed, JSTOR and Science Direct. The online search engine, Google Scholar was also used to search for and identify relevant papers. Peer-reviewed fulltext articles published in English on hypertensive adults in developing countries that measured adherence to antihypertensive medications and their associations with different factors were eligible for inclusion. The review followed the PRISMA reporting and analytical guidelines for systematic reviews. Results: In all, 42 studies conducted across 19 developing countries were selected for the review. The mean prevalence of medication non-adherence (MNA) among the select hypertensive population was 47.34%. Very few studies were conducted in community settings and except for one, no study examined gender differences in MNA factors. The analysis revealed a range of factors that can influence MNA including low household income and socioeconomic status; knowledge and beliefs of hypertension and its management; avoiding side effects of medications; cost of medication; use of herbal preparations; absence of symptoms; irregular follow-up; and dissatisfaction with the treatment and health services provided. There was a general lack of consideration of role of health system in health care delivery, self-efficacy, cultural barriers, per- There was also a lack of gender-specific research which is necessary at community settings given the social and economic vulnerabilities faced by women in developing countries that may affect adherence to antihypertensive medications. Conclusions: Future research in developing countries should consider individual risk perceptions, cultural barriers, gender and the role of local health system in health care delivery when assessing MNA among hypertensive population at community settings.

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“…The association of sex with adherence has in fact been found to be ambivalent in different studies with some associating it to better adherence, others such as the present one relating it to lower adherence and still no significant association in many of the studies 29 .…”

Section: Fig1: Level Of Adherence Among Study Participants (N=155)mentioning

confidence: 53%

“…According to the review made by Lin et al (2008), sex may not be a god predictor of adherence. Nevertheless, among studies that related sex to adherence is one reported locally from northwestern Ethiopia which reported significant association of the male sex with adherence to antihypertensive medication 15 .…”

Section: Fig1: Level Of Adherence Among Study Participants (N=155)mentioning

confidence: 99%

Untitled

2016

IJPSR

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Studies reported from Ethiopia depict poor health outcomes and management of diabetes cases and low patients" adherence to recommended regimens including medications. Among factors determining adherence to medications that are amenable to interventions are patient perceptions to their recommended medications. This study thus aimed to assess adherence to antidiabetic medications and determinant factors including medication related beliefs among type 2 diabetic patients attending their treatment in primary healthcare centers of Addis Ababa, Ethiopia using standardized measures. Methodology: A facility-based cross-sectional study design was followed to assess study participants recruited from among type 2 diabetic patients attending their treatment in three health centers in Kirkos Sub City, Addis Ababa from April to June, 2013. For the assessment interviewer administered structured questionnaires based on standardized measures such as the 8-item Morisk"s Medication Adherence Scale (MMAS) and the specific Belief about Medications Questionnaire (BMQ) were used. Result: A total of 155 study participants, all of whom were on oral hypoglycemic agents were involved in the study among whom 53.5% were male and 49.1% had maximum educational status of just being able to read and write. The findings into the medication adherence of the study participants indicated a mean MMAS score of 4.9±2.3 indicative of low adherence. The linear multiple regression model showed the male sex and concern about medications to have negative associations on patients" medication adherence. This might indicate the need for healthcare providers to assess medication-related beliefs and address safety concerns that patients may have.

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Factors affecting therapeutic compliance: A review from the patient’s perspective

Cited by 842 publications

References 149 publications

Compliance to antihypertensive medication: a cross-sectional study in Aligarh

Compliance to antihypertensive medication: a cross-sectional study in Aligarh

A Systematic Review of Factors Influencing Medication Adherence to Hypertension Treatment in Developing Countries

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