Factors Affecting The Development of Adverse Drug Reactions of Beta Blockers

Mugosa, Snezana; Todorović, Zoran; Sahman-Zaimovic, Majda; Radosavljevic, Ivan; Bukumirić, Zoran; Djordjević, Nataša

doi:10.1016/j.clinthera.2015.05.115

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2016

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“…Th ey mainly include the combination of clinical, biological and genetic infl uences which are expressed on platelet function (Table 1) [9][10][11].…”

Section: Introductionmentioning

confidence: 99%

Clopidogrel-statin interaction: A missing links

Todorović

Ðukanović²,

Obradović³

et al. 2016

Hosp Pharm Int Multi J

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SUMMARYIntroduction: The use of clopidogrel is associated with a large variability in the response to this drug, wherein the results of the numerous studies indicate that even one out of three patients can be placed in the category of non responder. Corresponding section headings: Among the many causes of modifi ed pharmacodynamic eff ects of clopidogrel, special attention is addressed to the possible clopidogrel-statin interaction. Numerous studies have focused on this problem, but it still seems to be missing the right answer. Conclusion: This paper reviews some of the most important facts regarding concomitant use of clopidogrel and statins, and specifi c issues to be addressed for safe treatment of patients.

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“…Th ey mainly include the combination of clinical, biological and genetic infl uences which are expressed on platelet function (Table 1) [9][10][11].…”

Section: Introductionmentioning

confidence: 99%