Factors affecting survival and severe morbidity in infants weighing 750 g or less

Locatelli, Anna; Roncaglia, Nadia; Andreotti, Camilla; Toso, Laura; D’Oria, Valentina; Pezzullo, John C.; Ghidini, Alessandro

doi:10.1016/j.ajog.2003.10.373

Cited by 4 publications

(5 citation statements)

References 0 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…Earlier reports in neonatology have revealed a significant female advantage for survival and short-term outcomes. 9,11,[13][14][15][16][17][18] Our findings challenge these previous studies by showing similar survival rates in a large cohort of preterm infants according to our original study design. However, we found a greater mortality in male neonates born between 24 and 26 weeks' gestation when we excluded the outborn neonates.…”

Section: Discussioncontrasting

confidence: 62%

“…A gender advantage for female infants has been documented in premature infant survival. 9,11,[13][14][15][16][17][18] Female gender is also coupled with better respiratory outcome, as shown by the lower incidence of respiratory distress syndrome (RDS) and bronchopulmonary dysplasia (BPD) in this group. [19][20][21] A greater incidence of retinopathy of prematurity (ROP) also has been recognized in male preterm infants.…”

mentioning

confidence: 99%

See 1 more Smart Citation

Role of Gender in Morbidity and Mortality of Extremely Premature Neonates

et al. 2011

View full text Add to dashboard Cite

We investigated the effect of gender on survival and short-term outcomes of extremely premature infants (≤27 weeks) born in Canada. The records of infants admitted between 2000 and 2005 to a neonatal intensive care unit participating in the Canadian Neonatal Network were reviewed for infant gender, birth weight, gestational age, outborn status, Score for Neonatal Acute Physiology II, and antenatal corticosteroid exposure. The following outcomes were recorded: survival at final discharge, necrotizing enterocolitis, bronchopulmonary dysplasia (BPD), intraventricular hemorrhage grade ≥3, retinopathy grade ≥3, days on ventilation, and length of hospital stay. Among 2744 extremely premature infants, 1480 (54%) were male and 1264 (46%) were female. Mean birth weight of female neonates was significantly lower at each week of gestational age. Although no significant difference in survival at discharge was found between genders overall, the prevalence of BPD, combined adverse outcomes, and mortality for infants born between 24 and 26 weeks were significantly higher in males. This study suggests that, in the postsurfactant era, males remain at higher risk of respiratory complications and may have higher mortality when born between 24 and 26 weeks of gestation.

show abstract

Section: Discussioncontrasting

confidence: 62%

mentioning

confidence: 99%

Role of Gender in Morbidity and Mortality of Extremely Premature Neonates

et al. 2011

View full text Add to dashboard Cite

show abstract

“…Males have generally been considered more vulnerable after premature birth. While male sex has been found to be a risk factor for mortality in birthweight‐based cohorts of extremely preterm infants, 9,10 this has not been so in two cohorts based on gestational age 11,12 . It is reassuring that maternal ethnicity did not appear to be a risk factor for death in this cohort given concern about inequalities in pregnancy outcomes for Maori and Pacific women in New Zealand 13,14 …”

Section: Discussionmentioning

confidence: 80%

Risk factors for and timing of death of extremely preterm infants

Elder¹,

Wong

Zuccollo

2009

Aust NZ J Obst Gynaeco

View full text Add to dashboard Cite

This study examined risk factors for timing and cause of death for extremely preterm infants > or = 23 weeks and < 28 weeks. There were 479 liveborn infants and 98 deaths reviewed over a ten-year period. Thirty-two deaths (33%) occurred on the first day of life and 72 (75%) in the first month of life. Lower gestation and intrauterine growth restriction were significant risk factors for death. Most deaths occurred in the first month of life and at the lowest gestation in the first week.

show abstract

“…In contrast, in other studies [17][18] people died within 7 days of giving birth. Locatelli et al found that smaller gestational age and birth weight, being female, having a low Apgar score at five minutes, and not getting steroids were all independent predictors of survival [19] . Kabilan et al [9] found that RDS, which leads to respiratory failure, was the main cause of death.…”

Section: Mortalitymentioning

confidence: 99%

Maternal risk factors and neonatal outcomes associated with neonates of birth weight <2 kg admitted to a neonatal intensive care unit of a tertiary care centre

AR¹,

Mirunalini²

2022

Int. J. Clin. Obstet. Gynaecol.

View full text Add to dashboard Cite

Background and Objectives: Infant mortality is one of the most important measures of health and growth in communities around the world. Low birth weight is one reason why infants die soon after birth. Low birth weight is affected by many social and economic factors, such as where a person lives (urban or rural), their level of education, the order of their children's births, the mother's nutrition, her Body Mass Index, the quality of prenatal care she received, and how far apart her children were born. This study aims at evaluating the maternal risk factors and neonatal outcomes for neonates of birth weight <2 kg admitted to a neonatal intensive care unit of a tertiary care centre. Methods: The study was a retrospective analysis of 150 babies weighing less than 2 kg, between October 2016 to October 2021. Neonatal resuscitation was done according to American Academy of Paediatrics. The maternal demographic profile, co-morbidities in the mother, factors such as gestational age at delivery, mode of delivery, birth weight were all recorded. Data were put into already-made forms, and statistical analysis was done. Results: Out of the 150 babies who weighed less than 2kg and were studied, 48 percent were boys and 52 percent were girls. The average weight at birth was 1.63 (SD = 0.28). Based on gestational age at delivery, most (28%) were born between 28 and 32 weeks, were small for their age (n=83, 55.3%), were born normally (n=81, 54%), were born alive (n=122, 81.3%), the mother was between 26 and 30 years old (n=66, 44%), had meconium aspiration syndrome (n=10, 6.75), was taking antenatal steroids (n=106, 70.7%), had a disease during pregnancy Most of the babies had respiratory distress syndrome (n=77, 51.3%), sepsis (n=31, 20.75%), or birth asphyxia (n=23, 15.3%). In this study, a death rate of 19.3% (n=24) was seen. Conclusion:In order to reduce the number of babies born with low birth weight, the public health strategy needs to focus on better nutrition and education for mothers.

show abstract

Factors affecting survival and severe morbidity in infants weighing 750 g or less

Cited by 4 publications

References 0 publications

Role of Gender in Morbidity and Mortality of Extremely Premature Neonates

Role of Gender in Morbidity and Mortality of Extremely Premature Neonates

Risk factors for and timing of death of extremely preterm infants

Maternal risk factors and neonatal outcomes associated with neonates of birth weight <2 kg admitted to a neonatal intensive care unit of a tertiary care centre

Contact Info

Product

Resources

About