“…38 During masticatory function, the microflow of bacteria from the microgap to the nearest attached mucosa and crestal bone 43 provides a pumping mechanism that may induce the formation of inflammatory connective tissues around the dental implant neck, 43 thus causing peri-implant mucositis, and subsequently, peri-implantitis. 6,7,9 Healthy connective tissue consists of different collagen components, such as collagen I, collagen III, collagen IV and collagen V. 44 Collagen IV is more frequently found in peri-implantitis than in healthy mucosa, and it has an ability to accelerate bacterial penetration. 44 Bibby found that the growth of bacterial flora was more pronounced around the posterior mandibular teeth, but no comparison had been made between the lingual and buccal regions.…”