Factors Affecting Quality of Life and Work Productivity among Patients with Gout

Abstract

Gout is the most common inflammatory arthritis today, affecting 4% of the adult US population. It is a serious disease that can significantly affect physical function and quality of life (QOL), where it has been advocated as an important outcome domain in studies of chronic gout. Aim of the study: To assess factors affecting quality of life and work productivity among patients with gout. Descriptive design: Was used to conduct the current study in rheumatology outpatient clinics, at Benha Teaching Hospital during the period from beginning of March 2018 till the beginning of September 2018. Subjects: Purposive sample of 168 patients recruited according to the study formula based on the total number of patients who admitted to the study settings during 2017. Tools: Three tools were utilized for data collection, structured interviewing questionnaire sheet, Medical Outcomes Study Questionnaire Short Form 36 Health Survey (SF-36) and Work Productivity and Activity Impairment Questionnaire. Results: Showed that both QOL as well as work productivity and activity impairment were best predicted by pain severity, diet aggravating frequency of attacks, nature of work as well as age. Besides, there was a negative and significant correlation (p= <0.001**) between quality of life and work productivity and activity impairment. Conclusion: Factors affecting QOL and Work productivity and activity impairment among patients with gout were concerning pain severity, diet aggravating frequency of attacks, nature of work as well as age. Besides, the impairment on different aspects of life is often negatively associated with impairment in work productivity and activity, where they were mainly affected by gout. Recommendation: Health educational instructions is required regarding pain management and diet regimen for patients with gout.

Impact of Endometriosis in Women of Arab Ancestry on: Health-Related Quality of Life, Work Productivity, and Diagnostic Delay

“…Participants completed the following standardized, validated questionnaires and instruments: Short Form-36 version 2 (SF36v2) ( 40 , 41 ) questionnaire, the World Endometriosis Research Foundation EPHect (WERF-EPHect) minimum clinical questionnaire (EPQ-M) version ( 42 ), and Work Productivity and Activity Impairment (WPAI) ( 43 , 44 ) questionnaire. Translations to the Arabic language, validated using the forward-backward translation method, of the questionnaires were utilized.…”

“…WERF-EPHect questionnaire (EPQ-M) were used to collect demographic information, measure the presence and severity of symptoms, risk factors, phenotypic profile and physical activity assessment ( 42 , 45 ). WPAI was used to measure absenteeism and presenteeism in employed women, and the impact of symptoms on activities ( 43 , 44 ).…”

“…The Work Productivity and Activity Impairment Questionnaire [WPAI; Cronbach alpha: English language (0.77–0.82) ( 43 , 57 ), Arabic language (0.71–0.76) ( 44 )] is a validated instrument that measures the effect of symptoms and disease on work productivity and daily tasks. The impact of the symptoms is measured by absenteeism (hours of missed work), presenteeism (perceived impairment of work tasks), work productivity loss (perceived loss in productivity levels) and activity impairment (impairment of patient's daily life activities).…”

“…WERF-EPHect questionnaire (EPQ-M) were used to collect demographic information, measure the presence and severity of symptoms, risk factors, phenotypic profile and physical activity assessment (42,45). WPAI was used to measure absenteeism and presenteeism in employed women, and the impact of symptoms on activities (43,44). Data were collected and managed in a web-based research electronic data capture (REDCap) (46) database, with 10% of the questionnaires inputted by two independent data processers to find discrepancies.…”

Cleroda-4(18),13-dien-15,16-olide as novel xanthine oxidase inhibitors: An integrated in silico and in vitro study

“…Any conditions that lead to the excessive accumulation of uric acid inside the body, for instance, low excretion and/or over-production will cause hyperuricemia, which in turn, could lead to a type of painful inflammatory arthropathy commonly known as gout [4,5]. The prevalence of gout varies across the world [6] and is estimated to occur in approximately 4.75% of European countries [6], 4% for USA [7], and >1% for Asia [6,8] and Africa [6]. It has been shown that gout patients had higher risk for developing cancer, particularly cancer of the lungs, urological and digestive systems [9].…”