Factors Affecting Posterior Capsule Opacification in the Development of Intraocular Lens Materials

Cooksley, Grace; Lacey, Joseph; Dymond, Marcus K.; Sandeman, Susan

doi:10.3390/pharmaceutics13060860

Cited by 27 publications

(19 citation statements)

References 119 publications

(275 reference statements)

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“…5,6 PCO is the main factor that affects vision recovery and causes blindness. 7 The incidence of PCO is about 20-40% in adults and almost 100% in children. 8,9 Nd:YAG laser capsulotomy is the only effective clinical treatment at present.…”

Section: Introductionmentioning

confidence: 99%

Design of foldable, responsively drug-eluting polyacrylic intraocular lens bulk materials for prevention of postoperative complications

Hong

Zou

et al. 2022

J. Mater. Chem. B

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Section: Introductionmentioning

confidence: 99%

Design of foldable, responsively drug-eluting polyacrylic intraocular lens bulk materials for prevention of postoperative complications

Hong

Zou

et al. 2022

J. Mater. Chem. B

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“…Previous research [4], [10] found that most patients were in the age range of 41 years to 80 years, and Ayuningtyas et al [8] showed a median age of 65 years with a range of 42 years to 87 years. In various studies [11], [12], [13], [14], [15], [16] , the period between patients who underwent cataract surgery and PCO formation has been reported to occur from five months to three years. In this study, PCO diagnosis was established after a median of 12 months, ranging from 8.2 months to 26.3 months after cataract extraction.…”

Section: Resultsmentioning

confidence: 99%

Posterior Capsule Opacification (PCO) Cases at Lamongan Eye Clinic: Two Years of Retrospective Data

Suryani

Unari

2022

VSEHJ

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Introduction: Posterior capsular opacity (PCO) is the most common complication of cataract surgery. PCO is caused by the lens epithelial cells (LEC), which then proliferate in the capsular bag after surgery. Several complications can occur, such as increased intraocular pressure (IOP), cystoid macular edema (CME), retinal hemorrhage, retinal detachment, and implanted lens (IOL) damage. Capsule Nd:YAG laser is currently the standard procedure for treating PCO, with a success rate of 95%. Purpose: This study aimed to provide an overview of PCO incidence and the success rate of PCO handling in the eye clinic. Methods: This study was a retrospective observational study. Data was taken from medical records of patients diagnosed with PCO who came to the Lamongan Eye Clinic for two years (May 2018 to April 2020). Data regarding the profile of the subject was analyzed descriptively. The data distribution was tested using the Kolmogorov-Smirnov test. Results: From May 2018 to April 2020, 134 patients with PCO came to the Lamongan Eye Clinic. Mean pre-laser best-corrected visual acuity (BCVA) was 0.76 ± 0.44 (logMAR), post-laser was 0.40 ± 0.40 (logMAR). There was a significant difference in the mean refraction correction of the PCO patients before and after Nd:YAG laser capsulotomy, whereas the mean BCVA after undergoing YAG laser was higher than before. Mean pre-laser IOP was 15.00 ± 3.55 mmHg and post-laser was 14.20 ± 3.27 mmHg. The mean post-laser IOP was lower than the pre-laser IOP. The Nd:YAG laser capsulotomy significantly affected IOP. Conclusions: There is a statistically significant improvement in BCVA before and after capsulotomy. Capsulotomy had a significant effect on improving BCVA up to 7%; however, had no effect on IOP.

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“…However, their visual axis was found to be clear six months after surgery, with the average age at surgery of 29.1 months. 23,24 Thus far, there is no data regarding rubella as the cause of infection that can initiate PCO occurrence.…”

Section: Discussionmentioning

confidence: 99%

Profile of Unilateral Cataract in Children With Congenital Rubella Syndrome

Yulia

Kirana²,

Soeharto³

2022

J. prof. medika

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A congenital cataract is preventable blindness in children and is associated with intrauterine rubella infection known as congenital rubella syndrome (CRS), mostly found in developing countries. This study aims to describe the profile of unilateral cataracts in children with CRS, which are more difficult to manage than bilateral ones. As a retrospective study, we reviewed complete medical records of children with CRS and unilateral cataracts at Cipto Mangunkusumo hospital from 2017 to 2020. Fifteen patients were included, mostly male and from outside Jakarta.The mean age of onset was 2.9 months, while the average age at first presentation and surgery was 27.7 months and 29.1 months, respectively.No correlation was found between patients’ residential distance from the hospital towards duration between onset of symptoms and first presentation to the hospital. 100% and 66.7% of patients had leukocoria and microcornea as ocular manifestations. The majority of systemic manifestations are congenital heart disease.66.7% of children underwent cataract surgery without IOL implantation. Improvement of visual acuity postoperatively was observed in 13.3% of patients, and 66.7% of patients used contact lenses for visual rehabilitation. 60% of patients had posterior capsule opacity within six months of follow-up. The challenge of wearing contact lenses in children makes the risk of amblyopia even greater

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Factors Affecting Posterior Capsule Opacification in the Development of Intraocular Lens Materials

Cited by 27 publications

References 119 publications

Design of foldable, responsively drug-eluting polyacrylic intraocular lens bulk materials for prevention of postoperative complications

Design of foldable, responsively drug-eluting polyacrylic intraocular lens bulk materials for prevention of postoperative complications

Posterior Capsule Opacification (PCO) Cases at Lamongan Eye Clinic: Two Years of Retrospective Data

Profile of Unilateral Cataract in Children With Congenital Rubella Syndrome

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