Factors affecting outcomes of prenatally‐diagnosed tumours

Abstract

Prenatally-diagnosed tumours without any other associated abnormality cause morbidity and mortality because of their location and vascularity. Solid tumours are relatively benign.

Prenatal presentation of cervical congenital neuroblastoma

“…Similar results regarding good outcome were found by a recent review of 15 prenatally diagnosed fetal tumors, in which all solid tumors (mesoblastic nephroma, neuroblastoma, sacrococcygeal teratoma) of the live births had no recurrence after surgery (Chan et al, 2002).…”

Fetal intervention for mass lesions and hydrops improves outcome: a 15-year experience

“…Postnatal surgical management avoids any maternal surgical risk and allows for the infant to be stronger for recovery at the time of surgery. One center reported success in postnatal resection of a 23-week GA, 680-g fetus with SCT of 208 g [8], but this is an exceptional case. Unfortunately for fetuses with many afflictions, waiting until after birth carries unacceptable risk and nearcertain mortality.…”

Prenatal diagnosis of fetal bilateral adrenal carcinoma

“…Fetal malignancies that are capable of metastasizing to other fetal organs, the placenta and, hypothetically, the mother, are exceedingly rare. The major histological types found among fetal congenital tumors are: teratomas, nephroblastomas, cardiac rhabdomyomas and neuroblastomas2. Although rare, reports of these benign tumors can be found in the literature.…”