Factors Affecting Adherence of Medication for Patients with Systemic Lupus Erythematous

Abstract

Background: Systemic Lupus Erythematosus (SLE) is a multisystem, autoimmune disease, it affect all organ systems or tissues, involvement of the skin, joints, central nervous system, and kidneys are among the most frequent manifestations. SLE is a chronic disease, the patients are generally treated with long-term regimens or even life-long immunomodulatory or immunosuppressive medications. Adhering to medications can be a challenge for patients with SLE. Objectives: This study aimed to identify the factors affecting adherence of medication for patients with systemic lupus erythematous. Setting: The study was conducted at the Blood Disease and Immunology inpatient Department of Alexandria Main University Hospital and the affiliated Outpatient Clinic. Subjects: This study comprised a convenience sample of 60 adult patients of both sexes and diagnosed with systemic lupus erythematous. Tools: three tools were used Tool I: Patient's Sociodemographic Characteristics , clinical data & Patient's Knowledge Structured Interview Schedule .Tool II Korean Version of the Hill-Bone Medication Adherence Subscale (HBMA-K) ,and tool III : Factors Affecting SLE patients' Adherence to medications checklist. Results: The study result revealed that more than half of studied patients had fair knowledge level regarding SLE. More than half of studied patients had low adherence to SLE medication, finally the patient related factors were the most factors affecting the adherence level on other hand Condition-related factors rated the lowest factors affecting the adherence level . Conclusion: this study revealed that more than half of the studied patient with SLE were low level adherence to their medications, and more than half of them had poor knowledge related to SLE disease. In addition to it was found that patient related factors are most factors affect medications adherence for SLE. Recommendations Develop and apply an educational sessions in order to improve patients knowledge regarding the SLE disease and consequence of non adherence with medication. provide communication between the healthcare provider and the patient, as well as simpler prescription regimens, to enhance medication adherence.

Effect of Online Teaching Instructions on Compliance among Patients Receiving Immunosuppressive Therapy

“…Regarding study participants' medical data, almost half of the participants discovered the disease between one to three years after symptoms appear. This finding is incongruent also with Mahmoud, Hawash, & Abd Elmaksoud, 2022 reported that most patients discovered the disease after suffering from the symptoms.…”

“…(2018) mentioned that poor treatment adherence is common among patients with multiple sclerosis (MS) and the reasons that are specific for non-adherence include a perceived lack of efficacy, forgetfulness, inconvenience of the regimen, adverse effects/tolerability issues and injection fatigue and/or anxiety. On the other hand, Mahmoud, Hawash, & Abd Elmaksoud, (2022) mentioned that systemic lupus erythematosus is associated with several factors that may make patients at especially high risk for treatment non-compliance, including cognitive and psychological manifestations, frequently complex treatment regimens, fluctuating symptoms, and a disproportionate prevalence of the disease among people of lower socioeconomic status After online instructions, the study results showed that the most apparent non-compliance items among the studied group were as follows: not enough sleep and not committing to wearing a mask while leaving out. These findings are matching Davide, et.…”