“…Both are known to be affected by changes in alveolar vol ume (Va). When Va decreases, TLC0 also de creases linearly, but Kc0 increases expon entially [2,9,12,14,16,17,20,21], This makes the interpretation o f these parameters difficult in patients with re duced lung volume. Recently our group [10] has developed a correction coefficient, Z, o f transfer factor, which allows correc-tion of TLco according to the alveolar volume in which the test is performed.…”