Factores perinatales asociados a la mortalidad neonatal en recién nacidos de muy bajo peso: estudio multicéntrico

Grandi, Carlos; Gonzalez, Agustina; Zubizarreta, José R.; Neocosur, Red Neonatal

doi:10.5546/aap.2016.426

Cited by 4 publications

(2 citation statements)

References 30 publications

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“…A study in 26 centers in six South American countries (31) found a birth mortality rate of 22.3% in premature infants of less than 37 weeks of gestational age, higher than in our study (4.29 per 1,000 live births). However, there was a high variability between centers.…”

Section: Discussioncontrasting

confidence: 86%

Sociodemographic determinants and mortality of premature newborns in a medium and low-income population in Colombia, 2017-2019

Torres-Muñoz,

Alberto Cedeño,

Murillo

et al. 2023

biomedica

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Introduction. The birth of premature babies is a public health problem with a high impact on infant morbidity and mortality. About 40% of mortality in children under five years occurs in the first month of life.Objective. To identify the association between maternal sociodemographic factors, premature birth, and mortality in newborns under 37 weeks in Santiago de Cali, 2017-2019. Materials and methods. We conducted a descriptive, cross-sectional study. We evaluated the records of Cali’s Municipal Public Health Office. We calculated the crude and adjusted odd ratios and confidence intervals (95%) using the logistic regression model, data processing in Stata 16, and georeferencing the cases in the QGIS software. Results. From 2017 to 2019, premature babies in Cali corresponded to 11% of births. Poor prenatal care increased 3.13 times the risk of being born before 32 weeks (adjusted OR = 3.13; 95% CI = 2.75 - 3.56) and 1.27 times among mothers from outside the city (adjusted OR = 1.27; 95% CI = 1.15-1.41). Mortality was 4.29 per 1,000 live births. The mortality risk in newborns weighing less than 1,000 g increased 3.42 times (OR = 3.42; 95% CI = 2.85-4.12), delivery by cesarean section in 1.46 (OR = 1.46; CI 95% = 1.14-1.87) and an Apgar score – five minutes after birth– lower than seven in 1.55 times (OR = 1.55; CI 95% = 1.23-1.96).Conclusions. We found that less than three prenatal controls, mothers living outside Cali, afro-ethnicity, and cesarean birth were associated with prematurity of less than 32 weeks. We obtained higher mortality in newborns weighing less than 1,000 g.

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Section: Discussioncontrasting

confidence: 86%

Sociodemographic determinants and mortality of premature newborns in a medium and low-income population in Colombia, 2017-2019

Torres-Muñoz,

Alberto Cedeño,

Murillo

et al. 2023

biomedica

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“… 1 An increasing number of very low birthweight (VLBW; BW <1500 g) babies are surviving till discharge in low/middle-income countries (LMICs). 2 Optimal nutrition is key for survival, prevention of adverse events such as sepsis and reducing the length of the hospital stay. 3 In addition, there is strong evidence that early nutrition impacts on multiorgan developmental patterning, immune, cardiac and respiratory function and longer term cognitive outcome as well as a range of chronic conditions such as diabetes and cardiovascular disease in adulthood which place a substantial burden on healthcare systems.…”

Section: Introductionmentioning

confidence: 99%

Evidence that informs feeding practices in very low birthweight and very preterm infants in sub-Saharan Africa: an overview of systematic reviews

Akindolire

Talbert

Sinha

et al. 2020

bmjpo

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BackgroundOptimal feeding of very low birthweight (VLBW <1500 g)/very preterm (gestation <32 weeks) infants in resource-limited settings in sub-Saharan Africa (sSA) is critical to reducing high mortality and poor outcomes.ObjectiveTo review evidence on feeding of VLBW/very preterm infants relevant to sSA.MethodsWe searched the Cochrane Database of Systematic Reviews, Embase, PubMed and Cumulative Index to Nursing and Allied Health Literature (CINAHL) from inception to July 2019 to identify reviews of randomised and quasi-randomised controlled trials of feeding VLBW/very preterm infants. We focused on interventions that are readily available in sSA. Primary outcomes were weight gain during hospital stay and time to achieve full enteral feeds (120 mL/kg/day). Secondary outcomes were growth, common morbidities, mortality, duration of hospital stay and cognitive development. Quality of evidence (QOE) was assessed using the Measurement Tool to Assess Systematic Reviews (AMSTAR2).ResultsEight systematic reviews were included. Higher feed volume of day 1 (80 mL/kg) reduced late-onset sepsis and time to full enteral feeds, and higher feed volume (up to 300 mL/kg/day) improved weight gain without adverse events (QOE: low–moderate). Rapid advancement of feeds (30–40 mL/kg/day) was not associated with harm. Breast milk fortification with energy and protein increased growth and with prebiotics increased growth and reduced duration of admission (QOE: low–very low) and did not result in harm. Evidence regarding feeding tube placement and continuous versus bolus feeds was insufficient to draw conclusions. We found no reviews meeting our selection criteria regarding when to start feeds, use of preterm formula, cup-and-spoon feeding or gravity versus push feeds and none of the reviews included trials from low-income countries of sSA.ConclusionsThe evidence base informing feeding of VLBW/very preterm babies in resource-limited settings in sSA is extremely limited. Pragmatic studies are needed to generate evidence to guide management and improve outcomes for these highly vulnerable infants.PROSPERO registration numberCRD42019140204.

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Growth phenotypes of very low birth weight infants for prediction of neonatal outcomes from a Brazilian cohort: comparison with INTERGROWTH

Cardoso¹,

Grandi²,

Silveira³

et al. 2023

Jornal de Pediatria

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Factores perinatales asociados a la mortalidad neonatal en recién nacidos de muy bajo peso: estudio multicéntrico

Cited by 4 publications

References 30 publications

Sociodemographic determinants and mortality of premature newborns in a medium and low-income population in Colombia, 2017-2019

Sociodemographic determinants and mortality of premature newborns in a medium and low-income population in Colombia, 2017-2019

Evidence that informs feeding practices in very low birthweight and very preterm infants in sub-Saharan Africa: an overview of systematic reviews

Growth phenotypes of very low birth weight infants for prediction of neonatal outcomes from a Brazilian cohort: comparison with INTERGROWTH

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