Factores Asociados al Incumplimiento de los Tratamientos con Antidepresivos en Santiago, Chile

Jirón, Marcela; Escobar, Leslie; Arriagada, Leonardo; Orellana, Sebastián; Castro, Ariel

doi:10.1016/j.jval.2011.05.035

Cited by 5 publications

(6 citation statements)

References 19 publications

(24 reference statements)

Supporting

Mentioning

Contrasting

Unclassified

Order By: Relevance

“…For example, cognitive behavior therapy is a common psychotherapy technique that has been shown to be more effective than other therapies [37]. Some unmeasured confounding patient-level characteristics were not available in our dataset, such as education [38], race [39], and socioeconomic status [40]. This study did not account for differences in criteria for disability leave among the plans and organizations including elimination period.…”

Section: Discussionmentioning

confidence: 99%

The influence of antidepressant and psychotherapy treatment adherence on future work leaves for patients with major depressive disorder

Gaspar¹,

Wizner²,

Morrison³

et al. 2020

BMC Psychiatry

View full text Add to dashboard Cite

Background Depression is the greatest contributor to worldwide disability. The purpose of this study was to understand the influence of antidepressant and psychotherapy treatment adherence on future work leaves for patients with major depressive disorder. Methods Patients with a newly diagnosed major depressive disorder (n = 26,256) were identified in IBM® Watson™ MarketScan® medical and disability claims databases. Antidepressant and psychotherapy adherence metrics were evaluated in the acute phase of treatment, defined as the 114 days following the depression diagnosis. Multiple variable Cox proportional hazards regression models evaluated the influence of antidepressant and/or psychotherapy adherence on future injury or illness work leaves. Results The majority of work leaves in the 2-year follow-up period occurred in the acute phase of treatment (71.2%). Among patients without a work leave in the acute phase and who received antidepressants and/or psychotherapy (n = 19,994), those who were adherent to antidepressant or psychotherapy treatment in the acute phase had a 16% (HR = 0.84, 95% CI = 0.77–0.91) reduced risk of a future work leave compared to treatment non-adherent patients. Patients who were non-adherent or adherent to antidepressant treatment had a 22% (HR = 1.22, 95% CI = 1.11–1.35) and 13% (HR = 1.13, 95% CI = 1.01–1.27) greater risk of a future work leave, respectively, than patients not receiving antidepressant treatment. Conversely, patients who were non-adherent or adherent to psychotherapy treatment had a 9% (HR = 0.91, 95% CI = 0.81–1.02) and 28% (HR = 0.72, 95% CI = 0.64–0.82) reduced risk of a future work leave, respectively, than patients not receiving psychotherapy treatment. Conclusions This analysis suggests that treatment adherence may reduce the likelihood of a future work leave for patients with newly diagnosed major depressive disorder. Psychotherapy appears more effective than antidepressants in reducing the risk of a future work leave.

show abstract

Section: Discussionmentioning

confidence: 99%

The influence of antidepressant and psychotherapy treatment adherence on future work leaves for patients with major depressive disorder

Gaspar¹,

Wizner²,

Morrison³

et al. 2020

BMC Psychiatry

View full text Add to dashboard Cite

show abstract

“…9 Neste questionário, não foi analisada a relação da adesão à terapêutica com capacidade financeira dos inquiridos. Contudo, trata-se de um factor reconhecidamente relevante, 17,18 pelo que ele deverá ser tido em conta em estudos futuros. Outros aspectos merecem atenção ulterior, nomeadamente quais os fármacos mais afectados pelas alterações efectuadas pelos doentes à medicação prescrita.…”

Section: Discussionunclassified

Influência dos factores financeiros no cumprimento da medicação

Chin

Alves

Martins

et al. 2012

RPMGF

View full text Add to dashboard Cite

artigosbreves INTRODUÇÃO O O cumprimento da terapêutica é uma temática complexa e multifactorial. 1 É influenciada por factores directamente relacionados com o doente, pela respectiva medicação e também pela situação económica do país e das pessoas. A identificação dos doentes que não aderem à terapêutica é difícil, mas essencial, para que se possa identificar e corrigir os seus motivos da não adesão, 2,3 uma vez que o não cumprimento da terapêutica é responsável pelo seu insucesso, pelo aumento dos custos com a saúde e pelo aumento da morbilidade e mortalidade. 4-7 Alguns estudos referem a ausência de evidência entre os factores socio-económicos e o grau de adesão à terapêutica. 1 No entanto, outros estudos internacionais referem que a subutilização medicamentosa por motivos financeiros varia entre 2% e 32%. 5-11 Além disso, alguns autores referem estar a verificar-se um agravamento do problema pois, num estudo realizado com uma população diabética americana, observou-se uma redução da adesão à terapêutica por factores financei

show abstract

“…Another study showed better adherence in females [36]. However, low-income females exhibited worse compliance [37,38]. Thus, the fear of undesired effects or disease relapse as well as, the anxiety of becoming addicted and the increased expenses leads to medication nonadherence.…”

Section: Factors Affecting Adherencementioning

confidence: 99%

Insight into improving antidepressant adherence and symptoms by pharmacist intervention: A review

Hassen¹,

Li²,

Yang³

et al. 2019

Trop. J. Pharm Res

View full text Add to dashboard Cite

Purpose: To assess the effectiveness of antidepressant medication adherence-improving intervention by a pharmacist and its impact on clinical symptoms of depression among outdoor depressive patients. Methods: Various databases such as PubMed, Embase, and Scopus were used sources for the literature published during the last 20 years. Pharmacist intervention studies involving adult depressed patients (≥ 17 years old) and treated with antidepressants were included. Twelve studies met the inclusion criteria. Results: These studies depicted various levels of interventions in which pharmacist counseled and educated the patients to support medication adherence. In only one of the studies, pharmacist intervention exercised significant effect on the depression features of patients. Conclusion: The findings suggest that the implication of antidepressant medication adherenceimproving intervention by pharmacist leads to the improved adherence of adult depressive patients to antidepressants. However, pharmacist intervention did not show any significant influence on depression symptomology, necessitating further studies on the topic.

show abstract

Factores Asociados al Incumplimiento de los Tratamientos con Antidepresivos en Santiago, Chile

Abstract: Antidepressant non-compliance was associated with income and sociodemographic characteristics in Chilean patients. Therefore, health strategies to improve AD compliance should consider inequities in access to medications and characteristics of the AD consumers.

Cited by 5 publications

References 19 publications

The influence of antidepressant and psychotherapy treatment adherence on future work leaves for patients with major depressive disorder

The influence of antidepressant and psychotherapy treatment adherence on future work leaves for patients with major depressive disorder

Influência dos factores financeiros no cumprimento da medicação

Insight into improving antidepressant adherence and symptoms by pharmacist intervention: A review

Contact Info

Product

Resources

About