Factor VIII elevation may contribute to portomesenteric vein thrombosis after laparoscopic sleeve gastrectomy: a multicenter review of 40 patients

Parikh, Manish; Adelsheimer, Andrew; Somoza, Eduardo; Saunders, John K.; Welcome, Akuezunkpa Ude; Chui, Patricia; Ren-Fielding, Christine; Kurian, Marina; Fielding, George; Chopra, Ajay; Goriparthi, Richie; Roslin, Mitchell; Afaneh, Che; Pomp, Alfons; Chin, Edward; Pachter, H. Leon

doi:10.1016/j.soard.2017.08.015

Cited by 15 publications

(11 citation statements)

References 15 publications

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“…Portomesenteric vein thrombosis (PMVT) is a rare but serious postoperative complication following laparoscopic bariatric procedures, with an incidence rate ranging from 0.3% to 1% 1. Due to the non-specific presenting symptoms of PMVT, a high index of suspicion is needed in order to make the diagnosis 1–3.…”

Section: Descriptionmentioning

confidence: 99%

“…In a recent multicentre review of 40 patients who developed PMVT after LSG, 92% had a haematological abnormality. The most common abnormality identified was elevation of Factor VIII (76%) 1. Other significant abnormalities included deficiencies in antithrombin III, factor V Leiden and protein C/S.…”

Section: Descriptionmentioning

confidence: 99%

“…However, with prompt diagnosis and expeditious treatment, up to 90% can be successfully treated with therapeutic anticoagulation alone 1. For these patients, the duration of anticoagulation remains somewhat ambiguous.…”

Section: Descriptionmentioning

confidence: 99%

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Portomesenteric vein thrombosis following laparoscopic sleeve gastrectomy: are underlying haematological disorders the culprit?

et al. 2018

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Section: Descriptionmentioning

confidence: 99%

Section: Descriptionmentioning

confidence: 99%

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Portomesenteric vein thrombosis following laparoscopic sleeve gastrectomy: are underlying haematological disorders the culprit?

et al. 2018

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“…Ожирение является дополнительным фактором высокого риска в развитии тромбоэмболических осложнений (ТЭО) у пациентов, требующих оперативного лечения [6; 7]. У пациентов с ожирением ТЭО развиваются в 2,5 раза чаще, чем у пациентов с нормальным индексом массы тела [7]. В настоящее время частота развития ТЭО с учетом принимаемых профилактических мер достигает 6,4%, Obesity is an additional high-risk factor in the development of thromboembolic complications (TEC) in the surgical treatment.…”

Section: особенности профилактики интраоперационных тромбоэмболическиunclassified

Prevention of thromboembolic complications in the laparoscopic treatment of obese patients

Burikov

Алексеевич²,

Skazkin

et al. 2018

Journal of Clinical Practice

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Obesity is an additional high-risk factor in the development of thromboembolic complications (TEC) in the surgical treatment. 110 cases of obese patients who underwent a treatment at the Surgical Department from January, 2015 to March, 2018. Prior to the operation, all the patients received a medication to prevent thromboembolic complications, while intermittent pneumocompression was applied during the surgery. The use of intermittent pneumocompression of the lower extremities in the laparoscopic surgical treatment of obese patients reduces the amount of venous thromboembolic complications via normalization of the intravenous haemodynamics

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“…Its elevation. Its deficiency leads to hemophilia, while elevation (> 150% of normal) is a risk for venous thrombosis [4].…”

Section: Introductionmentioning

confidence: 99%

A Case of Duodenal Resection and Duodenojejunostomy for Multiple Small Bowel Infarction in Patient With Inherited Thrombophilia and Vitamin K Antagonist Induced Critical Hypocoagulation

Kobalava¹,

Kvashilava

Giorgobiani³

et al. 2021

Cureus

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We present a case of the multiple venous intestinal infarction in patient with two inherited thrombophilias: Leiden factor V (LFV) and factor VIII elevation. The patient had a critical hypocoagulation caused by vitamin K antagonist (VKA) overdose. At laparotomy, several intestinal segments were necrotic and ischemic. Coagulopathy was corrected by the transfusion of the fresh frozen plasma. Because of the 4th duodenal segment infarction distal segmental duodenectomy with side-to-side duodenojejunostomy was done, which is a rarely performed procedure. On postoperative day 6 deep vein thrombosis developed, despite nadroparin profillaxes, early mobilisation and compressive stockings. Our case demonstrated that in patients with congenital thrombophilia, development of the mesenteric venous thrombosis is possible even with VKA induced severe hypocoagulation. Venous infarction of the small bowel can be associated with the hemoperitoneum and gastrointestinal bleeding. After resection of the fourth duodenal segment, side-to-side duodenojejunostomy is a feasible method of reconstruction.

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Factor VIII elevation may contribute to portomesenteric vein thrombosis after laparoscopic sleeve gastrectomy: a multicenter review of 40 patients

Cited by 15 publications

References 15 publications

Portomesenteric vein thrombosis following laparoscopic sleeve gastrectomy: are underlying haematological disorders the culprit?

Portomesenteric vein thrombosis following laparoscopic sleeve gastrectomy: are underlying haematological disorders the culprit?

Prevention of thromboembolic complications in the laparoscopic treatment of obese patients

A Case of Duodenal Resection and Duodenojejunostomy for Multiple Small Bowel Infarction in Patient With Inherited Thrombophilia and Vitamin K Antagonist Induced Critical Hypocoagulation

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