Factor analysis of rat behavior in an open field test

Markel, A. L.; Galaktionov, Yu. K.; Ефимов, В. М.

doi:10.1007/bf01236015

Cited by 49 publications

(32 citation statements)

References 11 publications

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“…Movement activity in dominant males was statistically significantly greater than in subordinates (Table 2). Differences between dominant and subordinate mice were clearest in measures of the vertical component of movement activity, supporting data indicating that leader individuals display pronounced investigative behavior [5].…”

Section: Assessment Of Primary Immune Responses and Measurement Of Thsupporting

confidence: 73%

Co-housing in a stable hierarchical group is not aversive for dominant and subordinate individuals

Vekovishcheva

Sukhotina

Zvartau

2000

Neurosci Behav Physiol

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The behavior of individuals and their responses to external stimuli are controlled by the microsocial environment, which for most mammals is associated with dominant-subordinate relationships. Physiological and behavioral differences between dominant and subordinate individuals may be 'primary' (genetically determined) or 'secondary' (due to position in the group's hierarchical structure). A series of experiments was conducted to investigate the physiological (pain response threshold), immunological (thymus, spleen weights, primary immune response), and behavioral (motor activity, behavior in a shuttle box test) characteristics of dominant and subordinate individuals in groups of three laboratory mice formed on the basis of linear hierarchy. Assessment of the effects of group conditions was made using a conditioned reflex location preference test. The results showed: 1) there are no statistically significant differences in physiological and behavioral (except for motor activity) parameters between dominant and subordinate mice; 2) co-housing of dominant and subordinate individuals in groups with stable hierarchical relationships was not aversive for them.KEY WORDS: Mice, dominance, subordinacy, stress, aggression, locomotor activity.Mouse-like rodents have territorial-hierarchical social structure [6] and in natural conditions dominant individuals expel subordinate individuals from their territory [16]. In laboratory conditions, where males are kept in a shared cage, despotic or strict dominance can be seen [15], where one male dominates and the others are subordinate. Some males of such a group can also show aggression, which is seen after removal of the most aggressive male (the ct male) [9]. Apart from high levels of aggression, the dominant animals is also characterized by behavioral features such as patrolling the territory and aggregating subordinate individuals [9], dominance with regard to access to water and food in conditions of deprivation [16], shorter latent periods tor first attacks on outlanders entering the patrolled territory, and higher frequencies and longer mean durations of attacks [2]. The tormation of 1Department of Psychopharmacology, A. V. Val'dman Institute of Pharmacology, Academician I. P. Pavlov St.

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Section: Assessment Of Primary Immune Responses and Measurement Of Thsupporting

confidence: 73%

Co-housing in a stable hierarchical group is not aversive for dominant and subordinate individuals

Vekovishcheva

Sukhotina

Zvartau

2000

Neurosci Behav Physiol

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“…Thus, the first exposure to a novel environment assay was not as indicative of personality as previously presumed. Indeed, factor analysis of behavioural responses in rodents has shown that first exposure could be affected by conflict resolution between fear and exploration (Markel et al 1989). Repeated exposure to the same assay reduces the novelty component, but it is likely that fish still found the brightly lit experimental arena threatening on their second exposure (Shuranova et al 2005).…”

Section: Discussionmentioning

confidence: 99%

Blood cortisol concentrations predict boldness in juvenile mulloway (Argyosomus japonicus)

Raoult

Brown

Zuberi

et al. 2011

J Ethol

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There is a growing interest in animal personality because individual variation is the substrate of the evolutionary process. Despite revelations that personality traits affect key fitness variables, little is known about the proximate mechanisms generating consistent behavioural differences between individuals. Boldness, the propensity to take risks, is one of the most widely studied aspects of personality in fishes. We assessed the position of juvenile Argyosomus japonicus on the ''boldness-shyness'' continuum by repeatedly recording the time taken to exit a refuge and explore a novel environment. Stress-related hormone concentrations after exposure to a mild stressor were analysed 1 month before behavioural assays and found to be significantly linked to boldness scores. Shy fish had significantly higher plasma cortisol concentrations in response to handling stress than bold fish. Spontaneous switching between personality categories occurred between trials, highlighting the importance of repeated testing of personality traits over time to correctly attribute personality.

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“…New approach to genetic variability VM Efimov et al Leamy, 1983;Markel et al, 1989). The results are set out in Table 3.…”

Section: Resultsmentioning

confidence: 99%

A new approach to the study of genetic variability of complex characters

2004

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A new approach to multivariate genetic analysis of complex organismal traits is developed. It is based on examination of the distribution of parental strains and the F 1 and F 2 hybrids in a multidimensional space, and the determination of the directions corresponding to heterozygosity, epistatic and additive gene effects. The effect of heterozygosity includes variability produced by interaction between and within heterozygous loci. The additive gene effects and the remaining epistatic interactions between the homozygous loci can be visualized separately from the effects of heterozygosity by an appropriate projection of the points in multidimensional space. In all, 20 morphological, physiological and behavioural characters and 21 craniometric measures were studied in crosses between two laboratory rat strains. Linear combinations of craniometric and of morphophysiological characters with a high narrow-sense heritability could be identified. These combinations characterized the organismal stress response, which had been selected for in one of the strains. The prospects for the practical application of the new approach and also for the evaluation of the contribution of the genetic diversity to phenotypic variability in animals in natural populations are discussed.

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Factor analysis of rat behavior in an open field test

Cited by 49 publications

References 11 publications

Co-housing in a stable hierarchical group is not aversive for dominant and subordinate individuals

Co-housing in a stable hierarchical group is not aversive for dominant and subordinate individuals

Blood cortisol concentrations predict boldness in juvenile mulloway (Argyosomus japonicus)

A new approach to the study of genetic variability of complex characters

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