Facilitation of short-term social memory by ethanol in rats is mediated by dopaminergic receptors

Prediger, Rui Daniel; Batista, Luciano C.; Miyoshi, Edmar; Takahashi, Reinaldo Ν.

doi:10.1016/j.bbr.2003.11.009

Cited by 35 publications

(21 citation statements)

References 63 publications

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“…This particular observation agrees with reports that a resident rat's social recognition memory of a juvenile intruder conspecific does not last more than 60 min when the duration of the first encounter is 30 min or less (4,(6)(7)(8)(9)(10)(11)(12)20).…”

Section: Discussionsupporting

confidence: 81%

“…The introduction of the familiar intruder within the resident's home cage for another 5-min encounter elicits far less social investigation compared to that which occurred during the prior encounter and that seen towards a novel intruder. However, this effect is only seen when the intertrial interval (ITI) is about 30-60 min but not when it is about 2 h (1,5,7,10); that is, at longer ITIs, the effect vanishes. This decreased social investigation during the second encounter with a familiar intruder, associated with a lack of decrease in social investigation towards a different intruder, is taken as evidence of social recognition memory.…”

Section: Introductionmentioning

confidence: 98%

“…Since many studies using the intruder-resident paradigm adopt a general "social behavior" category (1,6,9,11,17), which includes a diversity of behaviors that may, in fact, be characterized as social but not necessarily related to social investigation (e.g., mild aggression, rolling/standing over the juvenile and/or pushing it away, dominance, social grooming), their potential to detect social recognition memory may have been limited, as exemplified in the present study by the different statistical results when comparing social behaviors and social investigatory behaviors. In fact, some prior studies excluded aggressive behavior from the "social behavior" category (4,7,10,18).…”

Section: Critical Categories Of Social Behaviorsmentioning

confidence: 99%

“…This decreased social investigation during the second encounter with a familiar intruder, associated with a lack of decrease in social investigation towards a different intruder, is taken as evidence of social recognition memory. The intruder-resident paradigm has been used as a research tool to investigate short-term memory in rats (5,7,(10)(11)(12), and may potentially provide an animal model for investigating social interaction dysfunctions such as autism (13).…”

Section: Introductionmentioning

confidence: 99%

“…A popular behavioral model used to assess rodents' social recognition memory in the laboratory is the intruderresident paradigm (6)(7)(8)(9)(10)(11). Briefly, when an intruder conspecific is introduced within a resident male rat's home cage for a 5-min encounter, the resident rat exhibits intense social investigation activity towards the intruder.…”

Section: Introductionmentioning

confidence: 99%

See 4 more Smart Citations

Long-term social recognition memory in adult male rats: factor analysis of the social and non-social behaviors

Moura

Meirelles

Xavier

2010

Braz J Med Biol Res

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Section: Discussionsupporting

confidence: 81%

Section: Introductionmentioning

confidence: 98%

Section: Critical Categories Of Social Behaviorsmentioning

confidence: 99%

Section: Introductionmentioning

confidence: 99%

Section: Introductionmentioning

confidence: 99%

See 3 more Smart Citations

Long-term social recognition memory in adult male rats: factor analysis of the social and non-social behaviors

Moura

Meirelles

Xavier

2010

Braz J Med Biol Res

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Differential effects of acute amphetamine and phencyclidine treatment and withdrawal from repeated amphetamine or phencyclidine treatment on social interaction and social memory in rats

Munro

2012

PsyCh Journal

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Although animal models based on amphetamine (AMPH) or phencyclidine (PCP) treatment have been used extensively to study the neurobiological and behavioral characteristics of schizophrenia, there are conflicting reports regarding their validity in modeling the negative symptoms and cognitive deficits of schizophrenia. The present study examined how acute AMPH or PCP treatment (Experiment 1) and withdrawal from repeated AMPH treatment (Experiment 2) or PCP treatment (Experiment 3) affects social behavior and social recognition memory in male Sprague‐Dawley rats. Each subject was tested on two consecutive days. On the first day, the rats were tested four times (5 min/each) at 10‐min intervals with the same partner rat (termed “AAAA” day). One day later, the rats were tested with the previous partner in the first three sessions and with a new partner rat in the final session (termed “AAAB” day). The results show that acute AMPH treatment (1.5 mg/kg, sc) significantly reduced the time spent on social interaction, but did not affect social recognition on the first day. Acute AMPH only disrupted social recognition on the second day of drug testing. In contrast, acute PCP treatment (2.0 mg/kg, sc) had no effect on time spent on social interaction, but did significantly disrupt social recognition on both days. Withdrawal from repeated AMPH (3.0 mg/kg/day for 7 days, ip) or PCP (5.0 mg/kg/twice daily for 7 days, ip) treatment did not affect social interaction or social recognition, indicating a lack of long‐term detrimental effect of repeated AMPH or PCP treatment. These results suggest that acute AMPH treatment at a low dose (1.5 mg/kg) may be useful in modeling social withdrawal symptoms of schizophrenia, whereas acute PCP treatment at a similar dose range (2.0 mg/kg) may be useful in modeling the social cognitive deficit of schizophrenia.

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Blockade of adenosine and dopamine receptors inhibits the development of rapid tolerance to ethanol in mice

et al. 2005

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Facilitation of short-term social memory by ethanol in rats is mediated by dopaminergic receptors

Cited by 35 publications

References 63 publications

Long-term social recognition memory in adult male rats: factor analysis of the social and non-social behaviors

Long-term social recognition memory in adult male rats: factor analysis of the social and non-social behaviors

Differential effects of acute amphetamine and phencyclidine treatment and withdrawal from repeated amphetamine or phencyclidine treatment on social interaction and social memory in rats

Blockade of adenosine and dopamine receptors inhibits the development of rapid tolerance to ethanol in mice

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