Abstract:O‐carboxymethyl chitosan (CM‐chitosan), holds high potential as a valuable biomaterial for nerve guidance conduits (NGCs). However, the lack of explicit bioactivity on neurocytes and poor duration that does not match nerve repair limit the restorative effects. Herein, CM‐chitosan‐based NGC is designed to induce the reconstruction of damaged peripheral nerves without addition of other activation factors. CM‐chitosan possesses excellent performance in vitro for nerve tissue engineering, such as increasing the or… Show more
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