Facile synthetic pathway to β-hydroxy-β-trifluoromethyl imines and their derivatives

Loop, Ildiko; Skarpos, Hanna; Kalinovich, Nataliya; Kazakova, Olesya; Lork, Enno; Röschenthaler, Gerd‐Volker

doi:10.1016/j.jfluchem.2009.12.005

Cited by 5 publications

(1 citation statement)

References 20 publications

(20 reference statements)

Supporting

Mentioning

Contrasting

Order By: Relevance

“…The electron withdrawing groups in the previously reported crystalline gem-diol compounds include trichloromethyl, pyridyl, ester group etc except tetrazyl 1 – 7 . This discovery is very important to gem-diol chemistry since none of crystalline tetrazyl gem-diol compound has been reported until now.…”

Section: Introductionmentioning

confidence: 99%

Gem-diol and Ketone Crystal-to-crystal Transition Phenomena

Zhang

Sitong

Guo

et al. 2017

Sci Rep

View full text Add to dashboard Cite

The generally thought unstable diol compound tetrazyl gem-diol (1, H2DTMdiol·2H2O), was firstly obtained in crystalline form by culturing the filtrate for ten days after acidification and filtration of aqueous solution of potassium salt of ketone (2, [K(HDTMone)·2H2O]n). The stability of this novel gem-diol compound is found owning to the hydrogen bonds with lattice water molecules and electrophilic tetrazolyl groups. Meanwhile, the undissolved ketone (3, H2DTMone) was separated during the filtration in the process of gem-diol compound production. Surprisingly, the crystal-to-crystal perfect transition phenomena from gem-diol (1) to ketone (3) were firstly observed after heating up to 120 °C as evidenced by X-ray single crystal diffraction and powder X-ray diffraction. These results found here might open new revenues for methylene oxidation and alkanediol chemistry.

show abstract

Section: Introductionmentioning

confidence: 99%