Facile synthesis of water-soluble curcumin nanocrystals

Abstract

In this paper, facile synthesis of water soluble curcumin nanocrystals is reported. Solvent exchange method was applied to synthesize curcumin nanocrystals. Different techniques were used to characterize the structural and photophysical properties of curcumin nanocrystals. We found that nanocurcumin prepared by this method had good chemical and physical stability, could be stored in the powder form at room temperature, and was freely dispersible in water. It was established that the size of curcumin nanocrystals was varied in the range of 20-500 nm. Fourier transform infrared spectroscopy and UV-Vis analyses showed the presence of tetrahydrofuran inside the curcumin nanocrystals. Also, it was found that nanocurcumin emitted photoluminescencewith yellow-green colour. [Projekat Ministarstva nauke Republike Srbije, br. 172003]

Structural, mechanical, and antibacterial features of curcumin/polyurethane nanocomposites

“…The band at 1321–1186 cm −1 stem from CH 3 vibrations. The peak at 1120 cm −1 stem from OCH 3 vibrations . As for Cur/PU nanocomposites (curve 2), we could detect the same peaks as in curcumin sample shifted with a peak at 3400 cm −1 could be assigned to OH stretching vibrations whereas the peaks at 2940 and 2854 cm −1 belong to sp 2 and sp 3 CH stretching vibrations .…”

“…Curcumin is a very well‐known Indian spice used in many dishes especially in Asia. It is a major constituent of Curcuma longa L., or turmeric . Due to its unique physicochemical properties as well as pharmacological activities (antimicrobial, antidiabetic, anti‐inflammatory, anticancer, and antioxidant) it became an objective of many research .…”

Ambient light induced antibacterial action of curcumin/graphene nanomesh hybrids

“…50 The curcumin spectrum exhibits two absorption bands: the rst at 235 nm which is assigned to p-p transition of C-C bonds; and the second at 422 nm which is corresponded to n-p* transition of C]O bonds. 19 As for the curcumin-EHOPG sample, one absorption peak at 270 nm which corresponds to p-p transition of C-C bonds is detected. The second shoulder at 472 nm corresponds to n-p* transition of C]O bonds.…”

“…41 As for the curcumin sample (curve 2), we can identify several peaks which stemming from carbonyl groups (1744, 1714, 1640, 1517 cm À1 ) whereas the band at 1321-1186 cm À1 stem from CH 3 vibrations. 19 The peak at 1120 cm À1 stem from O-CH 3 vibrations. The peaks at 2830 and 2920 cm À1 which stemming from C-H stretching vibrations appears in the curcumin FTIR spectrum due to the presence of ethanol.…”

“…Commercially available curcumin is a mixture of three curcuminoids, namely, curcumin, demethoxy-and bisdemethoxy-curcumin, the latter two amounting to nearly 30% in samples labeled "pure". 19 It shows a remarkable range of pharmacological activity, including antioxidant, anti-inammatory and anticancer activity as well antibacterial. [20][21][22][23][24][25][26][27] Paunović et al found that photoexcited nanocurcumin displayed a signicant cytotoxicity depending both on the irradiation time and nanocurcumin concentration.…”