Facile Synthesis of Reduced Graphene Oxide‐octahedral Mn<sub>3</sub>O<sub>4</sub> Nanocomposites as a Platform for the Electrochemical Determination of Metronidazole and Sulfamonomethoxine

Xia, Yingcun; Ou, Xiaoqin; Zhao, Yan; Meng, Xiangjian; Chen, Dong; Gao, Wei‐Wei

doi:10.1002/elan.202100015

Cited by 15 publications

(2 citation statements)

References 59 publications

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“…In the literature, the use of different techniques was reported for separation or quantitative MNZ detection in environmental and biological samples, human plasma, drugs, and food products. They include high-performance liquid chromatography [ 11 ], liquid chromatography-tandem mass spectrometric method (LC-MS/MS) [ 12 ], chemiluminescence [ 13 ] fluorescence [ 14 , 15 ], near-infrared spectrophotometry (NIRS) [ 16 ], spectrophotometry [ 17 , 18 , 19 ], voltammetry with chemically modified electrodes [ 20 , 21 , 22 , 23 , 24 , 25 , 26 , 27 , 28 , 29 ].…”

Section: Introductionmentioning

confidence: 99%

Study on Metronidazole Acid-Base Behavior and Speciation with Ca2+ for Potential Applications in Natural Waters

et al. 2022

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Metronidazole (MNZ) is an antibiotic widely used for the treatment of various infectious diseases and as an effective pesticide agent for the cultivation of chickens and fish. Its high resistance to purification processes and biological activity has led to the classification of MNZ as an emerging contaminant. A speciation study, aimed to define the acid-base properties of MNZ and its interaction with Ca2+, commonly present in natural waters, is reported. The protonation constants of MNZ, as well as the formation constant value of Ca2+-MNZ species, were obtained by potentiometric titrations in an aqueous solution, using NaCl as background salt at different ionic strengths (0.15, 0.5, 1 mol L−1) and temperature (15, 25 and 37 °C) conditions. The acid-base behavior and the complexation with Ca2+ were also investigated by 1H NMR and UV-Vis titrations, with results in very good agreement with the potentiometric ones. The dependence of the formation constants on the ionic strength and temperature was also determined. The sequestering ability of MNZ towards Ca2+ was defined by the empirical parameter pL0.5 at different pH and temperature values. The speciation of MNZ simulating sea water conditions was calculated.

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Section: Introductionmentioning

confidence: 99%

Study on Metronidazole Acid-Base Behavior and Speciation with Ca2+ for Potential Applications in Natural Waters

et al. 2022

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“…In the last decade, graphene oxide and graphene oxide-based nanocomposites have been widely utilized for developing highly performed electrochemical nanosensors [15][16][17]. Graphene oxide is frequently being used due to its favorable features including excellent conductivity, large surface area, high chemical stability, low manufacturing cost, and mechanical strength [18][19][20].…”

Section: Introductionmentioning

confidence: 99%

Electrochemical Sensing Platform Based on Graphene Oxide‐chitosan for Simultaneous Determination of some Antihypertensive Drugs

et al. 2022

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The development of selective and simple methods for the determination of different analytes is of great interest. This is the first time to show the applicability of graphene oxide-chitosan (GO-CS) nanocomposite for designing an electrochemical nanosensor for determination of Amlodipine, Valsartan, and Hydrochlorothiazide, simultaneously. Differential pulse voltammet-rics current of AML, HCT, and VAL increased linearly in the ranges of 0.1-110, 0.1-110, and 1-230 μM with LOD of 5.5 × 10 À 2 , 3.5 × 10 À 2 and 8.6 × 10 À 2 μM, respectively. Finally, GO-CS/GCE was used for the detection of these drugs in commercial tablets and compared with the reference method (HPLC).

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Facile Synthesis of Reduced Graphene Oxide/Mn₃O₄ Nanocomposite as a Platform for the Voltammetric Determination of Tramadol

Sajjadi,

Beitollahi,

Garkani Nejad

2024

ChemistrySelect

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We describe a simple hydrothermal method for preparing a nanocomposite of reduced graphene oxide/Mn3O4 (rGO/Mn3O4), and its use in electrochemically detecting tramadol (TRA). The sensor was constructed by using a glassy carbon electrode modified with a rGO/Mn3O4 nanocomposite (rGO/Mn3O4/GCE) as an electro‐catalyst. The electrochemical properties of TRA at rGO/Mn3O4/GCE were studied using cyclic voltammetry (CV), chronoamperometry, and differential pulse voltammetry (DPV) in a phosphate buffer solution (PBS) with a pH of 8.0. The oxidation peak currents of TRA on rGO/Mn3O4/GCE increased compared to the bare GCE. This enhancement was attributed to the high surface area and excellent electron transfer performance of the rGO/Mn3O4 nanocomposite on the surface of the electrode. Under optimal conditions, the oxidation peak currents exhibited a linear increase with the concentration of TRA within the range of 0.5 to 700.0 μM, and a detection limit (LOD) of 0.16 μM was achieved. This study has shown that the rGO/Mn3O4/GCE can effectively be used to analyze TRA in real specimens.

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Facile Synthesis of Reduced Graphene Oxide‐octahedral Mn₃O₄ Nanocomposites as a Platform for the Electrochemical Determination of Metronidazole and Sulfamonomethoxine

Cited by 15 publications

References 59 publications

Study on Metronidazole Acid-Base Behavior and Speciation with Ca2+ for Potential Applications in Natural Waters

Study on Metronidazole Acid-Base Behavior and Speciation with Ca2+ for Potential Applications in Natural Waters

Electrochemical Sensing Platform Based on Graphene Oxide‐chitosan for Simultaneous Determination of some Antihypertensive Drugs

Facile Synthesis of Reduced Graphene Oxide/Mn₃O₄ Nanocomposite as a Platform for the Voltammetric Determination of Tramadol

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Facile Synthesis of Reduced Graphene Oxide‐octahedral Mn3O4 Nanocomposites as a Platform for the Electrochemical Determination of Metronidazole and Sulfamonomethoxine

Cited by 15 publications

References 59 publications

Study on Metronidazole Acid-Base Behavior and Speciation with Ca2+ for Potential Applications in Natural Waters

Study on Metronidazole Acid-Base Behavior and Speciation with Ca2+ for Potential Applications in Natural Waters

Electrochemical Sensing Platform Based on Graphene Oxide‐chitosan for Simultaneous Determination of some Antihypertensive Drugs

Facile Synthesis of Reduced Graphene Oxide/Mn3O4 Nanocomposite as a Platform for the Voltammetric Determination of Tramadol

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Product

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Facile Synthesis of Reduced Graphene Oxide‐octahedral Mn₃O₄ Nanocomposites as a Platform for the Electrochemical Determination of Metronidazole and Sulfamonomethoxine

Facile Synthesis of Reduced Graphene Oxide/Mn₃O₄ Nanocomposite as a Platform for the Voltammetric Determination of Tramadol