Facile synthesis of penta-substituted pyrroles and pyrrole-fused piperidin-4-ones via four component reactions of 2,3-diketoesters, anilines and enaminones

Abstract

Given the importance of pyrroles in pharmaceuticals, agrochemicals and functional materials, development of efficient strategies for their construction continues to be the hot area. Here, we present a novel BF3·Et2O...

Permanganate oxidation of α,β-unsaturated carbonyls to vicinal tricarbonyls

“…As a result, VTCs are highly reactive and can be used as useful synthons. 1,2 A series of carbo- and heterocyclic compounds can be obtained from VTCs, such as cyclopentane, 3 furan, 4 benzofuran, 5 pyrrole, 6 indole, 7 imidazole, 8 isoquinoline, 9 and quinoxaline. 10 VTCs have also been reported in the total synthesis of natural products.…”