Facile synthesis of nitrogen-doped carbon dots for Fe3+ sensing and cellular imaging

Gong, Xiaojuan; Lü, Wenjing; Paau, Man Chin; Hu, Qin; Wu, Xin; Shuang, Shaomin; Dong, Chuan; Choi, Martin M. F.

doi:10.1016/j.aca.2014.12.045

Cited by 285 publications

(141 citation statements)

References 70 publications

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“…Notably, the Fe 3+ ions can substantially quench the fluorescence of B-CDs, and the effect of other tested metal ions can be neglected. That is to say, the current probe based on B-CDs is highly selective toward Fe 3+ over other metal ions, which is better than some of the published work in literature [19,21,22,25].…”

Section: Sensitive and Selective Detection Of Fe 3+ Ionsmentioning

confidence: 82%

“…Since Fe 3+ can effectively quench the fluorescence of CDs [19][20][21][22][23][24][25][26], the capability of the current B-CDs as fluorescent probe to quantitatively detect Fe 3+ was also investigated. Figure 4b presents the relationship between the concentration of Fe 3+ ions and the relative fluorescent intensity (F/F 0 ) (F 0 and F are the fluorescence intensity at 359 nm in the absence and presence of ions, respectively).…”

Section: Sensitive and Selective Detection Of Fe 3+ Ionsmentioning

confidence: 99%

“…Therefore, accurate and fast determination of Fe(III) is an important issue in the environment and in biological systems. Up to now, numerous methods have been developed for the detection of Fe(III), including flame atomic absorption spectroscopy [14], mass spectrometry [15], electrochemical [16], and fluorescence detection [17][18][19][20][21][22][23][24][25][26]. Among these methods, fluorescence detection is a favorable method due to their high sensitivity, selectivity and fast detection.…”

Section: Introductionmentioning

confidence: 99%

“…Among these methods, fluorescence detection is a favorable method due to their high sensitivity, selectivity and fast detection. The increasing probes based on fluorescence quenching response of CDs have been studied recently [19][20][21][22][23][24][25][26]. All the probes show high sensitivity to Fe 3+ , however, some of them exhibit relatively poor selectivity due to the presence of Ag + [19], Pb 2+ [19,21], Hg 2+ [22,26], and Cu 2+ [25].…”

Section: Introductionmentioning

confidence: 99%

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Fluorescence quenchometric method for determination of ferric ion using boron-doped carbon dots

et al. 2015

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We report on the hydrothermal synthesis of borondoped carbon dots (B-CDs) starting from glucose and boric acid. Doping of the CDs with boron was confirmed by Fourier transform infrared and X-ray photoelectron spectroscopy. The B-CDs have an average diameter of about 4 nm and display blue fluorescence which is dynamically quenched by Fe(III) ions. This finding was exploited to design a method for the determination of Fe(III) in water. The relative fluorescence intensity at 359 nm in the presence and of absence ions is inversely proportional to the concentration of Fe(III) ions, and a Stern-Volmer calibration plot is linear in the concentration range of 0-16 μM, with a 242 nM detection limit. The assay is sensitive, robust and selective.

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Section: Sensitive and Selective Detection Of Fe 3+ Ionsmentioning

confidence: 82%

Section: Sensitive and Selective Detection Of Fe 3+ Ionsmentioning

confidence: 99%

Section: Introductionmentioning

confidence: 99%

Section: Introductionmentioning

confidence: 99%

See 2 more Smart Citations

Fluorescence quenchometric method for determination of ferric ion using boron-doped carbon dots

et al. 2015

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“…The discrimination effect for Fe(III) ions might originate from the exceptional coordination between Fe(III) ions and hydroxyl groups of CDs. 46 Besides metal ions, various anions and organic molecules that may co-exist with Fe(III) were observed under the same conditions. As shown in Fig.…”

Section: 44-47mentioning

confidence: 91%

A multianalyte fluorescent carbon dots sensing system constructed based on specific recognition of Fe(iii) ions

et al. 2017

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In this research, we developed a multianalyte fluorescence sensing system through a carbon dots (CDs)-based fluorescent probe that can specifically recognize Fe(III) by fluorescence quenching. The CDs prepared using black tea by a hydrothermal method show outstanding properties like low cytotoxicity, high photostability, excellent biocompatibility, and high sensitivity. It was found that the fluorescence of CDs can be quenched by micromolar concentrations of Fe(III) in both aqueous solutions as well as living cells. It is well known that glucose can be oxidized by glucose oxidase (GOx) to release H 2 O 2 , which, in turn, can oxidize Fe(II) to Fe(III). Based on this consideration, a multianalyte sensing system was established. Therefore the quantitative analysis of Fe(III), H 2 O 2 , and glucose with detection limits of 0.25 mM, 0.82 mM, and 1.71 mM, respectively, was achieved by the simple and cost-effective multianalyte CDs sensing system constructed. The sensing system showed high photostability and negligible cytotoxicity toward HeLa cells, which enables it to be applied in the visualization of Fe(III) or H 2 O 2 in living cells. The system was further applied in the detection of Fe(III) or glucose in human serum, and satisfactory results were obtained.

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Carbon‐Based Luminescent Nanosensors

López‐Lorente

2016

Encyclopedia of Analytical Chemistry

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Carbon nanomaterials have raised great attention in the past years for the development of luminescent nanosensors. These nanomaterials possess excellent photoluminescence properties, which combined with their low cytotoxicity and high biocompatibility make them ideal platforms for (bio)sensing. In this article, we have focused on recently developed fluorescent carbon nanomaterials such as graphene quantum dots, graphene oxide, and carbon dots, which have emerged as alternative to conventional dyes and semiconductor quantum dots. The different mechanisms underlying the sensors are discussed and examples of (bio)sensors involving these nanomaterials are described. The combination of two nanomaterials in the same sensing scheme has been widely employed in the past years combining both the emission properties of nanomaterials and their quenching ability. Finally, examples of sensors based on carbon nanomaterials developed for the determination of other nanomaterials of the same or different nature are presented.

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Facile synthesis of nitrogen-doped carbon dots for Fe3+ sensing and cellular imaging

Cited by 285 publications

References 70 publications

Fluorescence quenchometric method for determination of ferric ion using boron-doped carbon dots

Fluorescence quenchometric method for determination of ferric ion using boron-doped carbon dots

A multianalyte fluorescent carbon dots sensing system constructed based on specific recognition of Fe(iii) ions

Carbon‐Based Luminescent Nanosensors

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