Facile synthesis of fluorine-containing 1,10-phenanthrolines by the pyridine-ring formation reaction of N-propargyl-5,7-bis(trifluoroacetyl)-8-quinolylamine with amines: isolation of the intermediates 1,4-dihydro-1,10-phenanthrolin-4-ols

Three‐Component Coupling of Aldehydes, Amines, and Alkynes Catalyzed by Oxidized Copper Nanoparticles on Titania

“…Propargylamines are a versatile class of compounds extensively applied as precursors in the synthesis of heterocyclic compounds such as quinolines,1a phenanthrolines,1b pyrroles,1c pyrrolidines,1d indolizines,1e or oxazolidinones,1f among others 2. They have also been utilized as intermediates in the total synthesis of some natural and pharmaceutical products 3.…”

ZnCl2 loaded TiO2 nanomaterial: an efficient green catalyst to one-pot solvent-free synthesis of propargylamines

“…2 Three-component coupling of aldehyde, amine, and alkyne is one of the most extensively used methods for the preparation of several propargylamines through C-H bond activation. 3 Propargylamine derivatives play a signicant role in synthetic organic chemistry by acting as a versatile intermediate for the synthesis of many biologically active heterocyclic compounds such as 2-aminoimidazoles, 4 pyrrolidines, 5 pyrroles, 6 phenanthrolines, 7 oxazolidinones, 8 aminoindolizines, 9 etc. Moreover, they are the important structural ingredients of therapeutic drug molecules and also of natural products.…”

Super Paramagnetic, MCM-41-Supported, Recyclable Copper-Complexed Dendrimer: A Novel Nanostructured Catalyst for Propargylamine Synthesis Under Solvent-Free Conditions

“…Propargylamine is an important moiety in diverse biologically active natural materials, and can be utilized as a key intermediate for the synthesis of several bioactive compounds . Propargylamine derivatives have also been used as starting materials for the synthesis of heterocycles such as pyrroles, quinolones, phenanthrolines, pyrrolidines, indolizines, and oxazolidinones …”