2019
DOI: 10.13005/ojc/350612
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Facile Synthesis, Characterization and Antimicrobial Activities of Novel 6-AminoTriazolo-Thiadiazoles Integrated with Benzofuran and Pyrazole Moieties

Abstract: In the undertaken research we have reported simple efficient technique to afford a novel series of 3-(5-(benzofuran-2-yl)-1-phenyl-1H-pyrazol-3-yl)-N-aryl-[1,2,4]triazolo[3,4-b][1,3,4]thiadiazol-6-amine (4a-g) derivatives obtained by one pot cyclocondensation reaction of 5-(5-(benzofuran-2-yl)-1-phenyl-1H-pyrazol-3-yl)-4-amino-4H-1,2,4-triazole-3-thiol (3) with substituted aryl isothiocyanate in DMF and K2CO3, without formation undesirable side products by simple work up procedure. The structures yielded (4a-g… Show more

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